Basic pharmacokinetics and pharmacodynamics : an integrated textbook and computer simulations /

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Bibliografische gegevens
Hoofdauteur: Rosenbaum, Sara (Sara E.) (Auteur, Redacteur)
Formaat: Elektronisch E-boek
Taal:Engels
Gepubliceerd in: Hoboken, New Jersey : John Wiley & Sons, Incorporated, [2017]
Editie:Second edition.
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Online toegang:An electronic book accessible through the World Wide Web; click to view
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Inhoudsopgave:
  • Introduction to pharmacokinetics and pharmacodynamics
  • Passage of drugs through membranes
  • Drug administration and drug absorption / Steven Sutton
  • Drug distribution
  • Drug elimination and clearance
  • Compartmental models in pharmacokinetics
  • Pharmacokinetics of an intravenous bolus injection in a one-compartment model
  • Pharmacokinetics of an intravenous bolus injection in a two-compartment model
  • Pharmacokinetics of extravascular drug administration / Steven Sutton
  • Introduction to noncompartmental analysis
  • Pharmacokinetics of intravenous infusion in a one-compartment model
  • Multiple intravenous bolus injections in the one-compartment model
  • Multiple intermittent infusions
  • Multiple oral doses
  • Nonlinear pharmacokinetics
  • Introduction to pharmacogenetics
  • Models used to predict drug-drug interactions for orally administered drugs
  • Introduction to physiologically based pharmacokinetic modeling
  • Introduction to pharmacodynamic models and integrated pharmacokinetic--pharmacodynamic models / Diane Mould and Paul Hutson
  • Semi-mechanistic pharmacokinetic--pharmacodynamic model / Diane Mould and Paul Hutson.