Antibody-drug conjugates : fundamentals, drug development, and clinical outcomes to target cancer /

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Bibliographic Details
Other Authors: Olivier, Kenneth J., Jr., 1968- (Editor), Hurvitz, Sara A., 1970- (Editor)
Format: Electronic eBook
Language:English
Published: Hoboken, New Jersey : John Wiley & Sons, Incorporated, [2017]
Subjects:
Online Access:An electronic book accessible through the World Wide Web; click to view
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020 |z 9781119060680 (cloth) 
020 |z 9781119060680 
020 |a 9781119060802 (e-book) 
040 |a MiAaPQ  |b eng  |e rda  |e pn  |c MiAaPQ  |d MiAaPQ 
050 4 |a RS431.A64  |b A58 2017eb 
082 0 4 |a 615.7/98  |2 23 
130 0 |a Antibody-drug conjugates (Olivier) 
245 1 0 |a Antibody-drug conjugates :  |b fundamentals, drug development, and clinical outcomes to target cancer /  |c edited by Kenneth J. Olivier Jr. and Sara A. Hurvitz. 
264 1 |a Hoboken, New Jersey :  |b John Wiley & Sons, Incorporated,  |c [2017] 
264 4 |c �2017 
300 |a 1 online resource (566 pages) :  |b color illustrations 
336 |a text  |2 rdacontent 
337 |a computer  |2 rdamedia 
338 |a online resource  |2 rdacarrier 
504 |a Includes bibliographical references and index. 
505 0 |a Typical antibody-drug conjugates / John Lambert -- Selecting optimal ADC targets using indication-dependent or indication-independent approaches / Robert Hollingsworth and Jay Harper -- Antibody drug conjugates : an overview of the CMC and characterization process / Janet Wolfe and Phillip Ross -- Linker and conjugation technology and improvements / Riley Ennis and Sourav Sinha -- Formulation and stability / Kouhei Tsumoto, Anthony Young, and Satoshi Ohtake -- QC assay development / Xiao-Hong Chen and Mate Tolnay -- Occupational health and safety aspects of ADCs and their toxic payloads / Robert Sussman and John Farris -- Bioanalytical strategies enabling successful ADC translation / Xiaogang Han, Lindsay King, and Steve Hansel -- Nonclinical pharmacology and mechanistic modeling of antibody drug conjugates in support of human clinical trials / Brian J. Schmidt, Chin Pan, Heather E. Vezina, Huadong Sun, Douglas D. Leipold, and Manish Gupta -- Pharmacokinetics of antibody-drug conjugates / Amrita Kamath -- Path to market approval : regulatory perspective of ADC nonclinical safety assessments / Stacey Ricci and Natalie Simpson -- Antibody drug conjugates : clinical strategies and applications / Heather E. Vezina, Lucy Lee, Brian J. Schmidt, Manish Gupta -- Antibody-drug conjugates (ADCs) in clinical development / Patricia LoRusso and Joseph McLaughlin -- ADCs approved for use : Trastuzumab emtansine (Kadcyla, T-DM1) in patients with previously treated HER2-positive metastatic breast cancer / Gail Lewis Phillips, Sanne de Hass, Sandhya Girish, and Ellie Guardino -- ADCs approved for use : Brentuximab Vedotin / Sven DeVos and Monica Mead -- Radioimmunotherapy / Jeffrey Wong and Savita Dandapani -- Radiolabeled antibody-based imaging in clinical oncology / Bart Hendriks and Daniel Gaddy -- Antibody-drug conjugates : the next evolution in the cure for cancer -- William C. Olson and Amy Q. Han. 
588 |a Description based on print version record. 
590 |a Electronic reproduction. Ann Arbor, MI : ProQuest, 2016. Available via World Wide Web. Access may be limited to ProQuest affiliated libraries. 
650 0 |a Antibody-toxin conjugates. 
650 0 |a Monoclonal antibodies. 
650 0 |a Antineoplastic agents. 
650 0 |a Tumors  |x Treatment. 
655 4 |a Electronic books. 
700 1 |a Olivier, Kenneth J.,  |c Jr.,  |d 1968-  |e editor. 
700 1 |a Hurvitz, Sara A.,  |d 1970-  |e editor. 
776 0 8 |i Print version:  |a Antibody-drug conjugates (Olivier)  |t Antibody-drug conjugates : fundamentals, drug development, and clinical outcomes to target cancer.  |d Hoboken, New Jersey : John Wiley & Sons, Incorporated, [2017]  |z 9781119060680  |w (DNLM)101688103 
797 2 |a ProQuest (Firm) 
856 4 0 |u http://site.ebrary.com/lib/daystar/Doc?id=11300198  |z An electronic book accessible through the World Wide Web; click to view 
999 |c 198771  |d 198771