Integrated cardiac safety assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /
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Format: | Electronic eBook |
Language: | English |
Published: |
Hoboken, N.J. :
John Wiley & Sons,
c2009.
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Online Access: | An electronic book accessible through the World Wide Web; click to view |
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082 | 0 | 4 | |a 616.1/23061 |2 22 |
100 | 1 | |a Turner, J. Rick. | |
245 | 1 | 0 | |a Integrated cardiac safety |h [electronic resource] : |b assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / |c J. Rick Turner, Todd A. Durham. |
260 | |a Hoboken, N.J. : |b John Wiley & Sons, |c c2009. | ||
300 | |a xxviii, 470 p. : |b ill. | ||
504 | |a Includes bibliographical references (p. 397-455) and index. | ||
505 | 0 | |a The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety. | |
533 | |a Electronic reproduction. |b Palo Alto, Calif. : |c ebrary, |d 2013. |n Available via World Wide Web. |n Access may be limited to ebrary affiliated libraries. | ||
650 | 0 | |a Cardiovascular toxicology. | |
650 | 0 | |a Heart |x Effect of drugs on. | |
650 | 0 | |a Drugs |x Side effects |x Testing. | |
650 | 0 | |a Drugs |x Safety measures. | |
655 | 7 | |a Electronic books. |2 local | |
700 | 1 | |a Durham, Todd A. | |
710 | 2 | |a ebrary, Inc. | |
856 | 4 | 0 | |u http://site.ebrary.com/lib/daystar/Doc?id=10275622 |z An electronic book accessible through the World Wide Web; click to view |
908 | |a 170314 | ||
942 | 0 | 0 | |c EB |
999 | |c 95994 |d 95994 |