Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry /
Zapisane w:
| 1. autor: | |
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| Korporacja: | |
| Format: | Elektroniczne E-book |
| Język: | angielski |
| Wydane: |
Hoboken, N.J. :
Wiley,
c2011.
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| Hasła przedmiotowe: | |
| Dostęp online: | An electronic book accessible through the World Wide Web; click to view |
| Etykiety: |
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MARC
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| 020 | |z 9780470484067 (cloth) | ||
| 020 | |z 9781118140383 (e-book) | ||
| 035 | |a (CaPaEBR)ebr10558150 | ||
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| 100 | 1 | |a Peters, Sheila Annie. | |
| 245 | 1 | 0 | |a Physiologically-based pharmacokinetic (PBPK) modeling and simulations |h [electronic resource] : |b principles, methods, and applications in the pharmaceutical industry / |c Sheila Annie Peters. |
| 260 | |a Hoboken, N.J. : |b Wiley, |c c2011. | ||
| 300 | |a xvii, 430 p. : |b ill. | ||
| 504 | |a Includes bibliographical references and index. | ||
| 505 | 0 | |a Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain. | |
| 533 | |a Electronic reproduction. |b Palo Alto, Calif. : |c ebrary, |d 2011. |n Available via World Wide Web. |n Access may be limited to ebrary affiliated libraries. | ||
| 650 | 0 | |a Pharmacokinetics |x Mathematical models. | |
| 650 | 0 | |a Drugs |x Design |x Mathematical models. | |
| 655 | 7 | |a Electronic books. |2 local | |
| 710 | 2 | |a ebrary, Inc. | |
| 856 | 4 | 0 | |u http://site.ebrary.com/lib/daystar/Doc?id=10558150 |z An electronic book accessible through the World Wide Web; click to view |
| 908 | |a 170314 | ||
| 942 | 0 | 0 | |c EB |
| 999 | |c 137579 |d 137579 | ||