Applications of toxicogenomics in safety evaluation and risk assessment

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Awdur Corfforaethol: ebrary, Inc
Awduron Eraill: Boverhof, Darrell R., Gollapudi, B. Bhaskar
Fformat: Electronig eLyfr
Iaith:Saesneg
Cyhoeddwyd: Hoboken, N.J. : John Wiley & Sons, c2011.
Pynciau:
Mynediad Ar-lein:An electronic book accessible through the World Wide Web; click to view
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!
Tabl Cynhwysion:
  • Toxicology, "omics" technologies, and toxicogenomics : a primer
  • Introduction to human health risk assessment
  • Practical considerations for the application of toxicogenomics to risk assessment--early experience, current drivers, and a path forward
  • Approaches and practical considerations for the analysis of toxicogenomics data
  • Genomics in identifying mutagenic mode of action in carcinogenesis
  • Application of genomics for predicting and understanding the mode of action for non-genotoxic carcinogens
  • Genomics in characterizing endocrine toxicity
  • Studying organ specific toxicity using gene expression profiling
  • Toxicogenomic studies in human populations
  • Toxicogenomics applied to ecological risk assessment
  • Analysis of transcriptomic dose response data for toxicology and risk assessment
  • Toxicogenomics as a tool for validating animal to human extrapolations in chemical risk assessment: concepts, applications and challenges
  • Toxicogenomics and animal alternatives
  • Toxicogenomics and the regulatory framework
  • Standardization of gene expression information for the safety evaluation--activities in Japan -
  • Applying transcriptional profiling in drug safety evaluation
  • Reframing the risk assessment paradigm : towards a systems biology approach.