Gene discovery for disease models

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書目詳細資料
企業作者: ebrary, Inc
其他作者: Gu, Weikuan
格式: 電子 電子書
語言:英语
出版: Hoboken, N.J. : Wiley, c2011.
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書本目錄:
  • Introduction : gene discovery-from positional cloning to genomic cloning
  • High throughput gene expression analysis and the identification of expression QTLs
  • DNA methylation in the pathogenesis of autoimmunity
  • Ccell-based analysis with microfluidic chip
  • Missing dimension : protein turnover rate measurement in gene discovery
  • Bioinformatics tools for the prediction of gene function
  • Determination of genomic locations of targeted genetic loci
  • Mutation discovery using high throughput mutation screening technology
  • Candidate screening through gene expression profile
  • Candidate screening through high-density SNP array
  • Gene discovery through direct genome sequencing
  • Candidate screening through bioinformatics tools
  • Using an integrative strategy to identify mutations
  • Determination of the function of a mutant in a gene
  • Confirmation of a mutation by multiple molecular approaches
  • Confirmation of a mutation by microRNA
  • Confirmation of function of a gene by translational approaches
  • Confirmation of single nucleotide mutations
  • Initial identification and confirmation of a QTL gene
  • Gene discovery of crop diseases in the post genome era
  • Impact of whole genome genetic element analysis on gene discovery of disease models
  • Impact of whole genome protein analysis on gene discovery of disease models.