Integrated cardiac safety assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance /
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| 主要作者: | |
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| 格式: | 電子 電子書 |
| 語言: | 英语 |
| 出版: |
Hoboken, N.J. :
John Wiley & Sons,
c2009.
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| 主題: | |
| 在線閱讀: | An electronic book accessible through the World Wide Web; click to view |
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書本目錄:
- The importance of cardiac safety assessments
- The biological basis of adverse drug reactions
- Cardiac structure and function
- Cardiac pathophysiology and disease
- Drug discovery and drug design
- Nonclinical development
- The thorough QT/QTc trial
- General safety assessments
- Therapeutic use trials and meta-analyses
- Assessment methodologies in nonexperimental postmarketing surveillance
- Postmarketing proarrhythmic cardiac safety assessments
- Generalized cardiac safety
- Medication errors, adherence, and concordance
- Future directions in drug safety.