Statistical issues in drug development
Sábháilte in:
| Príomhchruthaitheoir: | |
|---|---|
| Údar corparáideach: | |
| Formáid: | Leictreonach Ríomhleabhar |
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
Chichester, England ; Hoboken, NJ :
John Wiley & Sons,
c2007.
|
| Eagrán: | 2nd ed. |
| Sraith: | Statistics in practice.
|
| Ábhair: | |
| Rochtain ar líne: | An electronic book accessible through the World Wide Web; click to view |
| Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
|
Clár na nÁbhar:
- A brief and superficial history of statistics for drug developers
- Design and interpretation of clinical trials as seen by a statistician
- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals
- The work of the pharmaceutical statistician
- Allocating treatments to patients in clinical trials
- Baselines and covariate information
- The measurement of treatment effects
- Demographic subgroups : representation and analysis
- Multiplicity
- Intention to treat, missing data and related matters
- One-sided and two-sided tests and other issues to do with significance and P-values
- Determining the sample size
- Multicentre trials
- Active control equivalence studies
- Meta-analysis
- Cross-over trials
- n-of-1 trials
- Sequential trials
- Dose-finding
- Concerning pharmacokinetics and pharmacodynamics
- Bioequivalence studies
- Safety data, harms, drug monitoring, and pharmaco-epidemiology
- Pharmaco-economics and portfolio management
- Concerning pharmacogenetics, pharmacogenomics, and related matters.