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Structure-based drug design targeting infectious disease

Table of Contents: “…Contents: Many antibiotics inhibit the ribosome -- Intelligent engine builds perpetual pipeline -- Crystallography shows 50S is a target-of-targets -- From new X-ray crystals to new leads -- Analog(Trade Mark) -- LINKER essentials: tethering two binding features -- BOMB essentials -- MUSIC essentials: core-swapping -- QikProp: calculating drug-like properties -- Structures + Analog(Trade Mark): balanced compounds -- Case study: enhanced oxazolidinones -- Structural foundations -- Path to enhanced oxazolidinones -- Pi contributions represent key interactions -- Probing selectivity of sparsomycin -- Seeking a new lead -- Difference density map showing rib-X prototype -- Perfect match -- A minimal scaffold for lead optimization -- Minimal scaffold binds effectively in A-site -- Activity against H. influenzae -- H. influenzae activity with time evolution -- H. flu model delivers differentiable oxazolidinones -- Moderate in vivo activity measured -- Predictive model for rat oral bioavailability -- First pool of drug candidates -- Structures + predictive models = time-saving filters.…”
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The nurse's contribution to clinical research and evidence-based practice

Table of Contents: “…Contents: The nurse's contribution to clinical research and evidence based practice -- How to identify the evidence to support decision making -- What are the sources of evidence and how to weigh its usefulness -- How to get evidence into action -- How to develop personal skills to support evidence based practice.…”
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Evidence-based practices for children with autism spectrum disorder

Table of Contents: “…Contents: Introduction to how evidence-based practice is being defined -- The application of evidence-based practice for the treatment of children with autism spectrum disorders -- Comprehensive treatment programs for children with autism spectrum disorders that have been shown to be evidence-based -- Focal treatments for children with autism that have been shown to be evidence-based -- Conclusions and future directions -- Additional readings, resources, and references.…”
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Current methods for the analysis of genetic case-control data a review /

Table of Contents: “…Contents: Genotype vs. haplotype penetrance models -- Likelihoods and fitting methods for case-control data -- Bayesian smoothing and clustering models -- Coalescent methods -- Haplotype sharing methods -- Haplotype blocks, htSNPs and the HapMap project.…”
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Roger Nash Baldwin and the American Civil Liberties Union / by Cottrell, Robert C., 1950-

Subjects: “…Baldwin, Roger N. (Roger Nash), 1884-1981.…”
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Evidence-based implant treatment planning and clinical protocols. /

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Usage-based approaches to language acquisition and language teaching /

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Through a glass darkly looking at conflict prevention, management, and termination / by Cimbala, Stephen J.

Subjects: “…Military policy Case studies.…”
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Tests of global governance Canadian diplomacy and United Nations world conferences / by Cooper, Andrew Fenton, 1950-

Subjects: An electronic book accessible through the World Wide Web; click to view

Prison, inc a convict exposes life inside a private prison / by Carceral, K. C.

Subjects: An electronic book accessible through the World Wide Web; click to view

Collaborative advantage winning through their extended enterprise supplier networks / by Dyer, Jeffrey H.

Subjects: “…Industrial procurement Case studies.…”
An electronic book accessible through the World Wide Web; click to view

Nature-friendly communities habitat protection and land use / by Duerksen, Christopher J., 1948-

Subjects: An electronic book accessible through the World Wide Web; click to view

Justice for Marlys a family's twenty-year search for a killer / by Munday, John S.

Subjects: “…Murder Minnesota Afton Case studies.…”
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The power of the Texas governor Connally to Bush / by McCall, Brian, 1958-

Subjects: “…Political leadership Texas Case studies.…”
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Doing time on the outside incarceration and family life in urban America / by Braman, Donald, 1968-

Subjects: “…Criminal justice, Administration of Social aspects United States Case studies.…”
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Smaldone the untold story of an American crime family / by Kreck, Dick

Subjects: “…Mafia United States Case studies.…”
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The political uses of expert knowledge immigration policy and social research / by Boswell, Christina

Table of Contents: “…The political functions of knowledge -- The puzzle : explaning the uses of knowledge -- Instrumental knowledge and organizational legitimacy -- The symbolic functions of knowledge -- The use of knowledge in public policy debates -- The case of immigration policy -- The politics of immigration in germany and the uk -- The British Home Office -- The German Federal Office for Migration -- The European Commission -- organizations and cultures of expertise -- Extending the theory -- Knowledge and policy.…”
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Policy and performance in American higher education an examination of cases across state systems / by Richardson, Richard C.

Table of Contents: “…Strengthening the policy-performance connection -- Rules in use and performance -- New Mexico / with contributions by Maria Emilia Martinez -- California / with contributions by Nancy Shulock -- South Dakota -- New York -- New Jersey / with contributions by Michael W. …”
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New demographics, new workspace office design for the changing workforce / by Myerson, Jeremy

Subjects: An electronic book accessible through the World Wide Web; click to view