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Forebrain mechanisms of pain modulation

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Functional pain disorders

“…Pain and the control of pain : pain transmission, regulation and management.…”
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The genetics of pain

Table of Contents: “…Contents: Variability in pain sensitivity and analgesia -- Heritability of pain -- Genetic and environmental contributions to pain -- Pain genes -- Monogenic pain disorders -- Association studies -- Inbred mouse strains and strain differences -- Genetic correlations among pain phenotypes -- Quantitative trait loci (QTLs) -- Melanocortin-1 receptors and pain -- Formalin test QTLs -- Haplotype mapping -- Atp1b3 and formalin pain.…”
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Opioid receptor pharmacology and pain

Table of Contents: “…Contents: Opioid receptors: relevance -- Opioids in pain management -- Opioid analgesics: pharmacology -- The endogenous opioid system -- Endogenous opioid peptides -- Effector systems -- Opioid receptor activation -- Opioid receptor mediated effects -- Opioid receptor polymorphisms -- Dimerization -- Internalization -- Endogenous opioids and opioid receptors are located at peripheral, spinal and supraspinal sites -- Opioid analgesia -- Cell transfection with a viral vector -- Viral vectors expressing endogenous opioid precursors -- Drugs that activate opioid receptors -- Opioid administration -- Paradoxical pain and tolerance -- Opioid-induced hyperalgesia: paradoxical pain -- Tolerance -- Peripheral opioid antagonists -- Clinical use of opioids -- Opioids in pain management -- Principle for safe and effective opioid use.…”
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Pain mechanisms in the spinal cord

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Primary afferent nociceptors

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Psychological approaches to pain

Table of Contents: “…Contents: Experience of pain and adaptation to persistent pain -- Negative mood influences pain and function over time -- Impact of depressive symptoms -- Clinically significant symptoms and diagnosis -- Persistent pain in primary care -- Catastrophizing: cognitive/affective response to pain -- Catastrophizing predicts persistence of pain -- Catastrophizing is associated with suicidal ideation -- High levels of catastrophizing may influence central modulation of pain -- Psychosocial considerations with every patient with chronic pain -- Promoting a self-management approach -- Psychosocial interventions in chronic pain -- Effects of psychosocial interventions in arthritis and chronic pain -- Cognitive behavioral treatment -- Mindfulness and acceptance treatment -- Sleep as an important target for behavioral interventions -- Managing the patient with affective disorder -- Patients may benefit from online cognitive therapy for depression.…”
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Sodium channels and pain

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Spinal drug delivery technology, biology and toxicology /

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Thalamo-cortical pain mechanisms

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Visceral pain and visceral hypersensitivity

Table of Contents: “…Contents: Visceral Pain -- Diffuse, referred and typically difficult to manage -- Visceral Hypersensitivity -- Defining characteristic of functional gastrointestinal disorders -- Contributed to by both peripheral and central mechanisms.…”
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Descending control systems

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Clinical pharmacology of pain

Table of Contents: “…Contents: Drugs used in pain management -- Drug administration -- Choosing the right analgesic -- Cancer pain -- Modified WHO ladder -- Opioid medication -- Inter-individual variation -- Pharmacokinetics and pharmacogenetics -- Adverse effects -- Half-lives of opioids -- Drug interactions -- How to treat adverse effects -- Neuropathic pain -- Anti-depressants -- Topical analgesics -- Adjuvant drugs -- Non-cancer pain -- Combinations of drugs -- New targets -- Guidelines.…”
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Pain processing in early life

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Cortical spreading depression and translational mechanisms in migraine headache

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Sodium channels and pain

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Series

The genetics of pain

Table of Contents: “…Contents: Variability in pain sensitivity and analgesia -- Heritability of pain -- Genetic and environmental contributions to pain -- Pain genes -- Monogenic pain disorders -- Association studies -- Inbred mouse strains and strain differences -- Genetic correlations among pain phenotypes -- Quantitative trait loci (QTLs) -- Melanocortin-1 receptors and pain -- Formalin test QTLs -- Haplotype mapping -- Atp1b3 and formalin pain.…”
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Series

Opioid receptor pharmacology and pain

Table of Contents: “…Contents: Opioid receptors: relevance -- Opioids in pain management -- Opioid analgesics: pharmacology -- The endogenous opioid system -- Endogenous opioid peptides -- Effector systems -- Opioid receptor activation -- Opioid receptor mediated effects -- Opioid receptor polymorphisms -- Dimerization -- Internalization -- Endogenous opioids and opioid receptors are located at peripheral, spinal and supraspinal sites -- Opioid analgesia -- Cell transfection with a viral vector -- Viral vectors expressing endogenous opioid precursors -- Drugs that activate opioid receptors -- Opioid administration -- Paradoxical pain and tolerance -- Opioid-induced hyperalgesia: paradoxical pain -- Tolerance -- Peripheral opioid antagonists -- Clinical use of opioids -- Opioids in pain management -- Principle for safe and effective opioid use.…”
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Pain mechanisms in the spinal cord

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Forebrain mechanisms of pain modulation

“…Pain and the control of pain : pain transmission, regulation and management.…”
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Series