Search Results - Health*

Evolution of virulence malaria : a case study /

Table of Contents: “…-- Possible selective effects of public health interventions -- Other infectious diseases -- Why evolutionary explanation matters.…”
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Ecogenetics evolutionary biology and human disease /

Table of Contents: “…-- Assessment, management and communication of health risks and genetic susceptibility to environmental chemicals.…”
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HIV/AIDS in the developing world what can we do? /

Table of Contents: “…-- Impact of current efforts -- Unique role for health professionals and scientists.…”
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Vitamin E and the metabolic syndrome

Table of Contents: “…Contents: Introduction to the role of vitamin E as an antioxidant -- Importance of vitamin E in human health -- Mechanisms of absorption and lipoprotein transport -- Introduction to the Metabolic Syndrome -- Pharmacokinetics of Vitamin E in healthy adults and those with metabolic syndrome -- Role of fat in vitamin E absorption -- Catabolism of vitamin E -- Introduction to a biomarker of vitamin E status; alpha-CEHC -- Demonstration of alpha-CEHC as a biomarker of bioavailability.…”
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Environmental effects on human reproduction

Table of Contents: “…Contents: Environmental effects on human reproduction -- Measuring reproductive ability -- Hormonal variation and ovarian function in different populations -- Effect of nutrition on reproductive function -- Effect of energetics on reproductive function -- Effect of genetics on reproductive function -- Developmental effects on reproductive function -- Immunological effects on reproductive function -- Hormones and health implications.…”
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Antiretroviral therapy 2007, new concepts and lessons learned

Table of Contents: “…Contents: Data from recent past about AIDS -- HIV life cycle and mechanisms of action of antiretroviral agents -- Nucleoside-nucleotide reverse transcriptase inhibitors (NRTIs/NtRTIs): potency, pharmacokinetics and adverse effects -- Non-nucleoside reverse transcriptase inhibitors (NNRTIs) -- Protease inhibitors (PIs) -- Cell entry inhibitors -- Initiation of antiretroviral therapy in the naive patient -- Health authorities' guidelines for initial therapy -- Key factors for improved durability -- Cell cycle and effect of antiviral agents -- Risks of early treatment -- New directions in antiretroviral therapy.…”
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Menopausal hormone therapy

Table of Contents: “…Contents: Menopause health risks -- Hormone therapy in perspective -- Reasons for continuing or initiating ERT/HRT -- HRT benefits -- Women's health initiative (WHI) -- Heart disease -- Effect of Estrogen on risk of CHD -- Breast cancer -- Increased risk of breast cancer detection is not the same as breast cancer mortality or causality -- The WHI did not consider disease latency -- Low doses are recommended -- Women's HOPE study.…”
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Predicting TSE transmission

Table of Contents: “…Contents: The TSEs continue to pose a problem to animal and human health -- The vCJD epidemic appears to be in decline but new risks of human to human transmission are now apparent -- Chronic wasting disease is a major problem currently in the US although its presence has not yet been detected in Europe -- Predicting and preventing transmission of disease requires an understanding of the routes of transmission within and between animals and the host factors which determine susceptibility -- We have studied natural disease and both in vivo and in vitro model systems to unravel the basic mechanisms of disease -- PrP protein has a central role in the outcome disease and mutations and polymorphisms in host PrP can profoundly alter the host's susceptibility to a TSE agent -- Precisely how host PrP influences the outcome of disease has not been established -- Both mutations and glycosylation can profoundly influence transmission both within and between species.…”
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Vitamin D endocrine system VDR binding, nutrition and drugs development /

Table of Contents: “…Contents: VDR conformational ensemble -- A vitamin D receptor ensemble model -- X-ray crystal structure of the nuclear vitamin D receptor -- VDR G- and A-pocket -- Vitamin D nutrition for good health -- Sources of vitamin D -- How much vitamin D do we need? …”
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Reproductive and developmental toxicology

Table of Contents: “…Contents: Assessing the risk of exposure to a new pharmaceutical is critical in providing information on the safe and effective use of any new product -- Reproductive and developmental toxicology is the study of the potential adverse effect of a drug, chemical, consumer product or medical device on the ability of a male and female to produce healthy normal children -- Adverse outcomes have lead to the safety testing that is mandated -- The guidelines that outline the safety testing required, the principles that these guidelines are based on and the potential hazard assessments that are made are based on the test results.…”
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The use of microarrays to understand the biology and toxicology of low dose arsenic

Table of Contents: “…Contents: Arsenic as an environmental chemical of concern for human health -- Use of microarrays to understand patterns of gene expression changes in response to low levels of toxic metals -- Development of non-parametric techniques for evaluating results of microarrays -- Use of patterns and biological pathways to understand microarray results -- Microarray analysis of low dose arsenic effects.…”
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Bariatric surgery techniques and mechanisms of action /

Table of Contents: “…Contents: Eastern North Carolina: an epidemiologic laboratory -- The Development of the gastric bypass -- Health effects of the gastric bypass -- Potential mechanisms of action -- Safety issues.…”
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Natural killer cell development

Table of Contents: “…Contents: Natural killer cells are versatile lymphocytes -- NK cells functions are important in health and disease: reproduction, cancer, transplantation, infection and autoimmunity -- Cell subsets, location and gene expression define functional heterogeneity -- Development influenced by MHC, stroma, transcription factors and cytokines -- Comparisons and contrasts between human and mouse NK cell development -- Uterine NK cells as ultimate example of specialized lineages of NK cells.…”
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Haemophilus

Table of Contents: “…Contents: Hemophilus influenzae -- Virulence determinants -- Immunization strategies -- Hib -- Other serotypes -- Basic structure of the H. influenzae LOS -- Sialic acids and virulence -- Phosphorylcholine (PCho) and virulence -- Phase variable genes -- Iron utilization systems -- Resistance to effectors of innate immunity -- Adhesins -- Other Haemophilus species associated with human health and disease -- Haemophilus ducreyi…”
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MRI approaches for neurovascular imaging

Table of Contents: “…Contents: Imaging neurovascular health and disease -- Magnetic Resonance Imaging -- Functional MRI -- Bold MRI -- Function MRI after cerebrovascular injury -- MRI of blood-brain barrier permeability -- Cellular MRI -- Molecular MRI -- MRI of neurovascular unit.…”
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Copy number variation

Table of Contents: “…Contents: Copy Number Variants (CNVs) -- Widespread structural variation among healthy humans -- Methods to detect CNVs -- Current state of CNV research -- Ongoing studies to characterize evolution and global distribution of CNVs.…”
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IBD for the non-gastroenterologist

Table of Contents: “…Contents: Clinical epidemiology and characteristics of IBD -- Diagnostic testing -- Medical treatment of UC and CD -- Adverse events with medications -- Assessing extraintestinal manifestations of IBD -- Complications of disease -- Alternative Therapies for IBD -- Vaccination advice -- Mental health issues -- Cancer screening.…”
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Epigenomics of complex disease

Table of Contents: “…Contents: Complex disease -- Non-mendelian features -- Epigenetic heritability -- Partial epigenetic stability -- Inherited and acquired epigenetic misregulation of genes and genomes -- Microarrays and epigenomic profiles in health and disease.…”
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The global burden of epilepsy

Table of Contents: “…Contents: The global burden of epilepsy -- Demographic and epidemiological aspects of Epilepsy around the world -- Outcome of epilepsy in resource-poor settings -- Aetiology and risk factors for epilepsy -- Epilepsy as a stigmatized condition -- Health seeking strategies and delivery of epilepsy care in resource-poor countries.…”
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Dengue and Yellow Fever the anatomy of decline and emergence/

Table of Contents: “…Contents: Dengue and Yellow Fever virus, are both Flaviviruses -- Epidemiology and transmission cycles -- History -- Effective control -- Re-emergence of epidemic dengue as global public health problem -- Reasons for emergence -- Threat of Yellow Fever as an emerging epidemic disease…”
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