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Colorectal cancer and the rare variant hypothesis

Table of Contents: “…Contents: Cancer: a somatic evolutionary process -- Colorectal cancer: a good model to study -- Two clear cut familial forms: FAP and HNPCC -- Mutation selection balance for dominants and recessives: application to FAP -- APC gene found by positional cloning -- Loss of heterozygosity proved its role in sporadic cancers -- Selection for mutations in the APC "mutation cluster region" -- HNPCC mismatch repair genes found by candidate guess -- Mutated genes in colorectal cancer include p53 and wnt pathway, occur in adenoma to carcinoma sequence -- Arguments for and against need for genomic instability in cancers -- Epigenetic changes -- Mathematical model of normal and cancerous crypt -- Types of familial cancers: mostly rarer than FAP and HNPCC -- Approaches to studying multifactorial inherited susceptibility -- HLA and disease: the model -- Role of linkage disequilbrium -- Principles of SNP association analysis -- Rare missense variants in the APC gene confer susceptibility -- The "rare variant hypothesis" for multifactorial inherited susceptibility: exemplified by study of colorectal adenomas.…”
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Storytelling : The Destruction of the Inalienable in the Age of the Holocaust / by Gasche, Rodolphe

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A Colonial Affair : Commerce, Conversion, and Scandal in French India / by Agmon, Danna, 1977-

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The Bodies That Remain

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Escribir la infancia : narradoras mexicanas contemporáneas /

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Spatial Analysis for Radar Remote Sensing of Tropical Forests. by De Grandi, G. F. (Gianfranco)

Table of Contents: “…Proxies of Forest Volume Loss and Gain by Differencing Insar Dsms: Fingerprints Of Forest Disturbance.…”
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Exile and suffering a selection of papers read at the 50th anniversary meeting of the Old Testament Society of South Africa OTWSA/OTSSA, Pretoria, August 2007 /

Table of Contents: “…a fresh look at Psalm 137 / Bob Becking -- The poetics of exile and suffering : memory and perceptions : a cognitive-linguistics study of Lamentations / Yehoshua Gitay -- The Exile as Sabbath rest : the Chronicler's interpretation of the Exile / Louis Jonker -- Lamenting the loss of lament, the language for our times / Frances Klopper -- Interpreting 'the Exile' in African Biblical scholarship : an ideo-theological dilemma in post-colonial South Africa / Gerald West.…”
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The crisis counseling and traumatic events treatment planner by Kolski, Tammi D.

Table of Contents: “…Machine generated contents note: PracticePlanners® Series PrefaceAcknowledgmentsIntroductionSample Treatment PlanAcute Stress Disorder*AnxietyBullying VictimChild Abuse/Neglect*Crime Victim Trauma*Critical Incidents with Emergency Service Providers (ESPs)*Depression*DisasterDomestic Violence*Job Loss*Medically Caused Death (Adult)*Medically Caused Death (Child)Miscarriage/Stillbirth/Abortion*Phobias*Posttraumatic Stress Disorder (PTSD)School Trauma (Pre-elementary)*School Trauma (Elementary)*School Trauma (Secondary)*School Trauma (College)*School Trauma (Staff)Sexual AssaultStalking Victim*Sudden/Accidental Death (Adult)*Sudden/Accidental Death (Child)*Suicide (Adult)*Suicide (Child)*Workplace ViolenceAppendix A: Bibliotherapy SuggestionsAppendix B: Professional References for Evidence-Based ChaptersAppendix C: Objective InstrumentsAppendix D: Index of DSM-IV-TR® Codes Associated with Presenting Problems* Indicates that selected Objective/Interventions are consistent with those found in evidence-based treatments.…”
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The Apple family : scenes from life in the country / by Nelson, Richard, 1950-

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Winning Marriage : The Inside Story Of How Same-Sex Couples Took On The Politicians And Pundits -- And Won / by Solomon, Marc, 1966-

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The Plight of Older Workers Labor Market Experience after Plant Closure in the Swiss Manufacturing Sector / by Baumann, Isabel

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Systemic RNA interference (RNAi) therapeutics for the treatment of HIV-1

Table of Contents: “…-- Major goals of anti-HIV therapies -- Combinatorial RNA based therapy for HIV -- Applying RNAi for the treatment of human diseases -- treat HIV infection by systemic delivery of small RNAs -- Aptamers -- Chimeric-siRNA aptamer uptake into gp120 expressing cells -- Aptamer-targeted RNA interference for HIV-1 therapy -- Aptamer and aptamer chimera mediated inhibition of HIV-1 -- Small animal model for studying anti-HIV RNAi based therapies -- Both aptamer and aptamer chimera inhibit HIV infection -Aptamer and chimeric aptamer-siRNA prevent CD4+ cell decline -- Aptamer and dsiRNAS effect on viral load -- Flexible PAMAM dendrimers with a triethanolamine core -- Dendrimers plus siRNAs form nanoparticles, protect siRNA from degradation and deliver siRNAs to T-lymphocytes -- G5 dendrimer delivered siRNAs down regulate target mRNAs in vitro -- Multiplex siRNAs for HIV-1 treatment -- In vivo analyses of G5 dendrimer delivered siRNAs -- Reductions in HIV loads following dendrimer siRNA injections -- Dendrimer-siRNA complexes protect HIV infected RAG-hu mice from CD4 T cell loss -- Bio distribution of G5 dendrimer siRNAs.…”
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Autonomous safety control of flight vehicles / by Yu, Xiang, 1981-

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Freedom within a framework : hearing the voice of the customer on the factory floor / by Cafaro, Paul G.

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Lactic acid fermentation of human excreta for agricultural application / by Andreev, Nadejda

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Black families and recession in the United States : the enduring impact of the Great Recession of 2007-2009 / by Smith-Ruiz, Dorothy, Kopak, Albert M.

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Antidote / by Van Landingham, Corey, 1986-

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A Colonial Affair : Commerce, Conversion, and Scandal in French India / by Agmon, Danna, 1977-

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Opioids: Addiction, Narrative, Freedom by Dolphin-Krute, Maia

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The Bodies That Remain

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