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Portal hypertension

Table of Contents: “…Contents: Portal hypertension causes regional circulatory derangements that result in extra- and intra-vascular volume overload and organ dysfunction -- Vascular tone is mediated by autonomic input and chemical mediators many of which are released by local vascular endothelium -- Intrahepatic portal hypertension develops as a result of anatomic changes in the cirrhotic liver that cause sinusoidal narrowing and loss of compliance -- Reflex SMA vasoconstriction and portosystemic shunting up-regulate VEGF eNOS and iNOS with resultant vasodilation -- There is secondary: ADH secretion with retention of free water; renal salt retention; renal afferent arteriolar vasoconstriction -- Affected individuals develop progressive volume overload with associated afterload reduction and increases in cardiac output (hyperdynamic circulation) -- Fluid is forced off the surface of the liver and accumulates in the abdominal cavity as ascites -- Blood is shunted around the liver through latent venous connections that become varices -- Renal function is impaired (hepatorenal syndrome) -- Volume overload may cause secondary pulmonary hypertension -- Affected individuals may also develop primary pulmonary hypertension due to anatomic alterations of pulmonary microvasculature (porto-pulmonary hypertension) -- The ability of the heart to respond to stress is impaired -- Patients develop intrapulmonary shunts that cause hypoxemia (hepatopulmonary syndrome) -- The only real remedy for these problems is orthotopic liver transplantation.…”
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Role of the PI 3-kinase signaling pathway in cell regulation and human disease

Table of Contents: “…Contents: Phosphoinositide 3-kinase (PI3K) signaling -- Class Ia PI3K's and the mediation of growth factor signaling -- The receptor tyrosine kinase signaling pathway -- Loss-of-function mutations in tumor suppressors -- Sporadic mutations -- Drug targets -- Regulation of metabolism by PI3K AKT signaling -- Targets of the drug NVP BEZ235 -- Generation of mice with mutant PI3K p110a -- How lung adenocarcinoma requires mutant PI3K -- HIF-1alpha -- Visualizing lung tumors using FDG PET -- How mTOR inhibition does not reduce tumor volume -- Will a PI3K inhibitor kill K-Ras driven tumors? …”
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The domestication of humans / by Bednarik, Robert G.

Taylor & Francis
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Plant pathology / by Burchett, Stephen, Burchett, Sarah

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Beyond the responsibility to protect in international law : an ethics of irresponsibility / by Samara, Angeliki

Taylor & Francis
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Religious entrepreneurism in China's urban house churches : the rise and fall of Early Rain Reformed Presbyterian Church / by Ma, Li (Sociologist)

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Radio frequency micromachined switches, switching networks, and phase shifters / by Koul, Shiban K., Dey, Sukomal

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RAS pathway and disease neurofibromatosis and beyond /

Table of Contents: “…Contents: Neurofibromatosis type 1 (NF1) -- NIH diagnostic criteria (Seven criteria for NF1) -- NF1 and the RAS pathway -- NF1 tumour biology -- Neurofibromin deficiency -- Two types of neurofibromas -- Plexiform neurofibroma in the neck and mouth -- Mechanisms of disease -- Mouse models of neurofibroma formation -- Imatinib mesylate treatment -- Clinical aspects of glomus tumours of fingertips -- Gastrointestinal stromal tumours -- MPNST in NF1 -- FDG-PET as a diagnostic tool -- Hotspots for recombination & NF1 microdeletion -- SUZ12-loss -- Cafe-au-lait (CAL) macules -- Skeletal defects in NF1 -- Learning disabilities in NF1 -- Simvastatin treatment for cognitive deficits -- Mosaicism for NF1 mutation -- Diagnostic problems -- SPRED1 mutations & molecular mechanism of Legius syndrome -- The RAS pathway proteins & genetic syndromes (RASopathies).…”
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Role of the PI 3-kinase signaling pathway in cell regulation and human disease

Table of Contents: “…Contents: Phosphoinositide 3-kinase (PI3K) signaling -- Class Ia PI3K's and the mediation of growth factor signaling -- The receptor tyrosine kinase signaling pathway -- Loss-of-function mutations in tumor suppressors -- Sporadic mutations -- Drug targets -- Regulation of metabolism by PI3K AKT signaling -- Targets of the drug NVP BEZ235 -- Generation of mice with mutant PI3K p110a -- How lung adenocarcinoma requires mutant PI3K -- HIF-1alpha -- Visualizing lung tumors using FDG PET -- How mTOR inhibition does not reduce tumor volume -- Will a PI3K inhibitor kill K-Ras driven tumors? …”
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Imperial Physique by Phrydas, JH

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Making Home(s) in Displacement : Critical Reflections on a Spatial Practice

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Fundamentals of nursing : the art and science of nursing care /

Table of Contents: “…Introduction to nursing -- Cultural diversity -- Health and illness -- Health of the individual, family, and community -- Theory, research, and evidence-based practice -- Values, ethics, and advocacy -- Legal implications of nursing -- Healthcare delivery systems -- Continuity of care -- Home healthcare -- Blended skills and critical thinking throughout the nursing process -- Assessing -- Diagnosing -- Outcome identification and planning -- Implementing -- Evaluating -- Documenting, reporting, conferring, and using informatics -- Developmental concepts -- Conception through young adult -- The aging adult -- Communicator -- Teacher and counselor -- Nurse leader and manager -- Vital signs -- Health assessment -- Safety, security, and emergency preparedness -- Asepsis and infection control -- Complementary and alternative therapies -- Medications -- Perioperative nursing -- Hygiene -- Skin integrity and wound care -- Activity -- Rest and sleep -- Comfort -- Nutrition -- Urinary elimination -- Bowel elimination -- Oxygenation -- Fluid, electrolyte, and acid-base balance -- Self-concept -- Stress and adaptation -- Loss, grief, and dying -- Sensory functioning -- Sexuality -- Spirituality.…”

Collaborative intervention in early childhood consulting with parents and teachers of 3- to 7-year-olds / by Hirschland, Deborah

Table of Contents: “…-- Seven building blocks of development: understanding core emotional, behavioral, and social competencies -- The contribution of constitution: understanding a child's temperament and neurodevelopmental profile -- The contribution of family life: understanding a family's history and patterns of interaction -- Setting the stage for mastery: developing a working hypothesis, goals for growth, and a plan of action -- Home-based strategies: helping parents set effective behavioral expectations -- Classroom-based strategies: mentoring teachers in the skills of developmental scaffolding -- Helping the shy, cautious, or withdrawn child -- Helping the child with language and information processing issues -- Helping the high energy and/or inattentive child -- Helping the easily frustrated, impulsive child -- Helping the anxious child -- Helping the disengaged, offbeat, or gifted but rigid child -- Additional issues: addressing trauma and loss, monitoring media choices, providing guidance during crises, and more -- Elementary school and beyond: perspectives for the long haul.…”
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Role of the PI 3-kinase signaling pathway in cell regulation and human disease

Table of Contents: “…Contents: Phosphoinositide 3-kinase (PI3K) signaling -- Class Ia PI3K's and the mediation of growth factor signaling -- The receptor tyrosine kinase signaling pathway -- Loss-of-function mutations in tumor suppressors -- Sporadic mutations -- Drug targets -- Regulation of metabolism by PI3K AKT signaling -- Targets of the drug NVP BEZ235 -- Generation of mice with mutant PI3K p110a -- How lung adenocarcinoma requires mutant PI3K -- HIF-1alpha -- Visualizing lung tumors using FDG PET -- How mTOR inhibition does not reduce tumor volume -- Will a PI3K inhibitor kill K-Ras driven tumors? …”
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RAS pathway and disease neurofibromatosis and beyond /

Table of Contents: “…Contents: Neurofibromatosis type 1 (NF1) -- NIH diagnostic criteria (Seven criteria for NF1) -- NF1 and the RAS pathway -- NF1 tumour biology -- Neurofibromin deficiency -- Two types of neurofibromas -- Plexiform neurofibroma in the neck and mouth -- Mechanisms of disease -- Mouse models of neurofibroma formation -- Imatinib mesylate treatment -- Clinical aspects of glomus tumours of fingertips -- Gastrointestinal stromal tumours -- MPNST in NF1 -- FDG-PET as a diagnostic tool -- Hotspots for recombination & NF1 microdeletion -- SUZ12-loss -- Cafe-au-lait (CAL) macules -- Skeletal defects in NF1 -- Learning disabilities in NF1 -- Simvastatin treatment for cognitive deficits -- Mosaicism for NF1 mutation -- Diagnostic problems -- SPRED1 mutations & molecular mechanism of Legius syndrome -- The RAS pathway proteins & genetic syndromes (RASopathies).…”
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Making Home(s) in Displacement : Critical Reflections on a Spatial Practice

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Hope or hype the obsession with medical advances and the high cost of false promises / by Deyo, Richard A.

Table of Contents: “…how to get the "right" answer in clinical research -- "Cancer cured--film at 11:00": the media's role in disseminating medical advances -- Doctors and hospitals: fueling the drive for new and more -- Advocacy groups: Mother Teresa's waiting room -- Holes in the safety net: the FDA and the FTC -- Ineffective. inferior or needlessly costly new drugs -- Medical devices that disappoint -- Ineffective or needlessly extensive surgery -- Weight loss technology: shedding pounds from your waistline or your wallet? …”
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Realism's Empire : Empiricism and Enchantment in the Nineteenth-Century Novel / by Baker, Geoffrey, 1973-

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Insect pests of stored grain : biology, behavior, and management strategies / by Kumar, Ranjeet, 1982-

Table of Contents: “…Introduction to storage entomology -- History of grain or seed storage -- Classification and identification of important stored grain/seed insects -- Important stored grain and seed insect pests -- Detection of infestation in stored product -- Estimation of losses due to insects in stored products -- Sources and kind of infestation -- Factors affecting infestation of storage insects -- Methods of storage and different storage structures -- Behavioral management of storage insects -- Management of stored grain and seed insects by plant products -- Integrated management of storage insects -- Fumigation of stored products -- Important mites associated with stored produce and their management -- Important birds associated with stored grain and their management -- Important rodents in warehouse or godown and their management -- Important storage fungi and their management -- Stored grain insects of quarantine importance.…”
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Remains of the Social : Desiring the post-apartheid /

Table of Contents: “…Traversing the social / Maurits van Bever Donker [and three others] -- The Mandela imaginary : reflections on post-reconciliation libidinal economy / Derek Hook -- The return of empathy : postapartheid fellow feeling / Ross Truscott -- The ethics of precarity : Judith Butler's reluctant universalism / Mari Ruti -- Hannah Arendt's work of mourning : the politics of loss, 'the rise of the social' and the ends of apartheid / Jaco Barnard-Naud{acute}e -- Souvenir / Annemarie Lawless -- Re-cover : Afrikaans rock, apartheid's children and the work of the cover / Aiden Erasmus -- The graves of Dimbaza : temporal remains / Gary Minkley and Helena Pohlandt-McCormick -- The principle of insufficiency : ethics and community at the edge of the social / Maurits van Bever Donker -- The Trojan Horse and the 'becoming technical of the human' / Premesh Lalu.…”
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