Search Results - "yeast"

The microbial models of molecular biology from genes to genomes / by Davis, Rowland H.

Table of Contents: “…Model systems, model organisms -- Morgan's progeny -- Neurospora -- Aspergillus -- Yeast -- Leaving the fungi -- Escherichia coli -- The T bacteriophages -- Temperate phages and transduction -- DNA -- Prokaryotes take center stage -- Prokaryotes : later contributions -- Cytoplasmic inheritance : the ciliates -- Organelle genetics : yeast and chlamydomonas -- Yeast becomes a supermodel -- The filamentous fungi : eclipse and renewal -- The role of biochemistry -- Genomics -- The age of model organisms.…”
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Computational methods in analysis of gene regulation and protein interactions

Table of Contents: “…Contents: Finding regulatory motifs -- Finding motifs using target sets of promoters -- Problem definition -- The Amadeus motif finding algorithm -- Architecture, benchmark results and global analysis -- Finding transcriptional programs and their regulatory motifs -- Problem definition -- The Allegro software for recovering transcriptional program -- Results on yeast osmotic shock expression profiles -- Recovering microRNA binding motifs from 3' UTRs using stem cell expression profiles -- Discovering a novel motif pair in C. elegans -- Utilizing network information -- Using expression and protein interaction data -- Problem definition and the Matisse algorithm -- Demonstration of Matisse on yeast osmotic shock data -- Comparison of Matisse to other algorithms -- Demonstration of Matisse on human stem cell data -- The pluripotency network -- Using expression and protein interaction data with interaction confidence -- The Cezanne algorithm -- DNA damage response in yeast.…”
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Hsp104 a specialized chaperone for protein disaggregation /

Table of Contents: “…Contents: Heat shock -- Molecular chaperones and thermotolerance -- Protein aggregation and refolding -- Prions in mammals and yeast -- Molecular chaperones and protein aggregation associated with human disease.…”
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Introduction to applied molecular biology

Table of Contents: “…Contents: Molecular biology -- Polymerase chain reaction and the enzymes that make cloning possible -- Examples of applied molecular biology techniques in health and disease -- Cloning in bacteria, yeast and eukaryotes -- GMOs and regulation.…”
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Roles for Hsp40 molecular chaperones in protein misfolding disease

Table of Contents: “…Contents: Protein aggregation in conformational disease -- The Hsp40 system -- The Hsp70 system -- Small oligomers, prion, yeast, Huntington's disease and protein triage -- Mechanisms for proteotoxicity -- Mechanisms for amyloid disease.…”
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Protein networks and analysis of global gene expression

Table of Contents: “…Contents: A paradigm shift: from databases of protein sequences to protein interactions -- Technologies for measuring interactions -- Chromatin immunoprecipitation (ChIP) -- Yeast Two Hybrid (Y2H) technology -- Mass spectrometry based approaches -- Methods for querying protein networks with gene expression profiles -- Systematic validation of protein network models using gene deletions -- Cytoscape open-source software for network modeling and visualization -- Methods for network comparison across species -- Application to discover conserved protein complexes among the networks of yeast, worm, fly and Plasmodium -- Methods for querying protein networks to explain genetic (synthetic lethal) interactions -- Future directions: how network queries will enable systems biology.…”
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The ERAD network

Table of Contents: “…Contents: Eukaryotic secretory pathway -- ER processes -- ERAD steps -- Substrate recognition -- Glycans as sorting signals -- Yeast ERAD process -- Mammalian ERAD process -- ERAD adapter proteins -- ERAD translocons -- ERAD E3 ligases.…”
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Computational modelling of GPCR signalling dynamics

Table of Contents: “…Contents: GPCRs signalling kinetics can be modelled using simple equations -- Link between computational modelling and pharmacology -- Yeast are excellent system for computational models -- RGS proteins show non-intuitive activity -- Kinetic models of GPCRs can model agonist bias.…”
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Mechanisms of mitochondrial fusion and fission

Table of Contents: “…Contents: Mitochondrial ultrastructure -- Mitochondrial organization in the cytosol -- Mitochondria-shaping proteins -- Dynamins and the dynamin superfamily -- Control of mitochondrial shape in yeast -- Control of mitochondrial morphology in mammals -- Mitochondrial fusion and the transmission of mitochondrial DNA -- Changes in mitochondrial ultrastructure during apoptosis -- Mitochondrial fragmentation during apoptosis -- Cristae remodeling and OPA1.…”
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Infectious diseases of wild mammals and birds in Europe

Table of Contents: “…Bacterial Infections -- Mycobacteria infections -- Yersinia infections -- Tularaemia -- Pasteurella infections -- Brucellosis -- Anthrax -- Chlamydiaceae infections -- Borrelia infections -- Rickettsiales infections : Rickettsia, Anaplasma and Ehrlichia species -- Mycoplasma infections -- Escherichia infections -- Salmonella infections -- Campylobacter infections -- Leptospira infections -- Coxiella burnetii infection -- Listeria infections -- Clostridium species infections and botulism -- Other bacterial infections -- Section III. Fungal and yeast infections -- Aspergilloss -- Yeast infections -- Other fungal infections -- Harmful algal blooms or cyanobacterial toxicosis -- Mycotoxicosis --…”
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mRNA capping

Table of Contents: “…Contents: Modification of mRNA 5' ends by addition of a m7G cap structure -- Capping for viability -- Conservation in yeast to humans -- Structure of caps and capping enzymes -- Mechanism of cap synthesis -- Protein-protein interactions that link capping to events in transcription, transport and translation -- siRNA knockdown experiments.…”
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Dynamic signal encoding in the S. cerevisiae calcium response

Table of Contents: “…Contents: Calcium and Signaling -- Excessive calcium causes cellular stress -- Signaling pathways are turned on to combat this stress -- In budding yeast, these pathways involve nuclear translocation of transcriptional regulator Crz1 -- Examination of this regulator shows that nuclear translocation occurs in "bursts" -- Bursts are quantized and frequency-modulated -- Frequency modulation enables proportional expression of downstream target genes.…”
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Biology is technology the promise, peril, and new business of engineering life / by Carlson, Robert H., 1970-

Table of Contents: “…-- Building with biological parts -- Learning to fly (or yeast, geese, and 747s) -- The second coming of synthetic biology -- A future history of biological engineering -- The pace of change in biological technologies -- The international genetically engineered machines competition -- Reprogramming cells and building genomes -- The promise and peril of biological technologies -- The sources of innovation and the effects of existing and proposed regulations -- Laying the foundations for a bioeconomy -- Of straightjackets and springboards for innovation -- Open-source biology, or open biology? …”
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Cytoplasmic epigenetics proteins acting as genes /

Table of Contents: “…Contents: Prions (infectious proteins) include several self-propagating amyloids of S. cerevisiae and Podospora anserina and a self-activating enzyme of S. cerevisiae -- these non-chromosomal genetic elements are genes composed of protein, just as nucleic acids can catalyse enzymatic reactions -- the amyloid-based prions [PSI+] and [URE3] are diseases of yeast, but the [Het-s] prion of Podospora carries out a normal function for that organism, heterokaryon incompatibility.…”
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Yiddishlands a memoir / by Roskies, David G., 1948-

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Analysis of protein-protein interaction, transcriptional regulation and metabolic networks

Table of Contents: “…Contents: Biological networks: small networks dedicated to a specific task and genome-scale networks -- Protein interaction networks -- The yeast two-hybrid assay and its limitations -- Graph theory: degree distribution and correlation, characteristic path lengths and diameter, clustering coefficient, abundance of motifs and indicators of modularity -- Measures of node and edge centrality -- Affinity chromatography -- Hypergraphs -- Protein microarrays -- Transcription regulation networks -- Metabolic networks -- Small-world networks -- Flux balance analysis.…”
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Replication licensing

Table of Contents: “…Contents: Problems in ensuring complete genome replication -- Experiments revealing the existence of a replication licence -- The licensing reaction -- ORC, Cdc6, Cdt1 and Mcm2-7 -- Cell cycle regulation of licensing -- Pre-RC substrates in yeast -- Regulation of licensing in animal cells by Cdt1 degradation and geminin inhibition -- Is there a licensing checkpoint? …”
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Molecular biology and biotechnology

Table of Contents: “…The expression of foreign DNA in bacteria -- Ch. 5. Yeast cloning and biotechnology -- Ch. 6. Cloning genes in mammalian cell-lines -- Ch. 7. …”
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Enhancer malfunction in cancer

Table of Contents: “…Contents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? …”
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Deciphering neurodegeneration models and methods /

Table of Contents: “…Contents: Deciphering Neurodegeneration: Models and Methods -- The challenge of neurodegeneration -- Huge diversity in cell types -- Nature versus nurture -- Reductionism versus systems biology -- Cellular models -- Yeast -- Primary cells -- Cell lines -- Stem cells -- Model organisms -- Caenorhabditis elegans -- Drosophila melanogaster -- Zebrafish -- Danio rerio -- Rodents -- Molecular biology approaches -- Knock out and knock in -- Genomic editing -- RNAi -- Overexpression -- Gene expression -- rtPCR -- Microarrays -- RNAseq -- Protein analysis -- Immunoblot -- ELISA -- Mass spec and proteomics -- Microscopy -- Immunocytochemistry -- Live cell imaging -- Electrophysiology.…”
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