Search Results - "transcription factor"

Stem cells from the early embryo

Table of Contents: “…Contents: Stem cells from the early mammalian embryo -- Mouse embryonic development -- Blastocyst reconstitution experiments -- Lineage specific transcription factors -- Lineage specific stem cell lines.…”
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Polydactyl zinc finger proteins software and hardware for genomes /

Table of Contents: “…Contents: Development of a universal system for gene regulation -- A diversity of recognition domains -- Phage display -- Targeted endogenous gene regulation in cells and organisms -- The specificity issue and genome size -- Genomic specificity requires polydactyl proteins -- Transcription factor libraries: a powerful new strategy -- Cutting and pasting genes and genomes -- Zinc finger enzymes and designer epigenetic modifications -- Zinc finger nucleases: scissors for genome surgery -- Recombinases -- Gene delivery vehicles.…”
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Polydactyl zinc finger proteins software and hardware for genomes /

Table of Contents: “…Contents: Development of a universal system for gene regulation -- A diversity of recognition domains -- Phage display -- Targeted endogenous gene regulation in cells and organisms -- The specificity issue and genome size -- Genomic specificity requires polydactyl proteins -- Transcription factor libraries: a powerful new strategy -- Cutting and pasting genes and genomes -- Zinc finger enzymes and designer epigenetic modifications -- Zinc finger nucleases: scissors for genome surgery -- Recombinases -- Gene delivery vehicles.…”
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Polydactyl zinc finger proteins software and hardware for genomes /

Table of Contents: “…Contents: Development of a universal system for gene regulation -- A diversity of recognition domains -- Phage display -- Targeted endogenous gene regulation in cells and organisms -- The specificity issue and genome size -- Genomic specificity requires polydactyl proteins -- Transcription factor libraries: a powerful new strategy -- Cutting and pasting genes and genomes -- Zinc finger enzymes and designer epigenetic modifications -- Zinc finger nucleases: scissors for genome surgery -- Recombinases -- Gene delivery vehicles.…”
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Use of isolated populations in disease gene identification

Table of Contents: “…Contents: Disease mutations in Finland - Molecular background of Finnish disease heritage - Finnish disease genes, novel pathways exposed - Example: APECED - AIRE protein - AIRE regulates ectopic expression in thymus - AIRE deficiency - Simplifying the complex genetic background of common diseases - Advantages of isolated populations - Internal isolates: increased genetic homogeneity - Lactose intolerance - Adult type hypolactasia - Severe coronary heart disease - Familial combined hyperlipidemia, FCHL - USF1: a transcription factor - Effect of genetic association on target cells, coronary wall and impact in population - Population based cohorts in Finland - Global effort is needed.…”
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Use of isolated populations in disease gene identification

Table of Contents: “…Contents: Disease mutations in Finland - Molecular background of Finnish disease heritage - Finnish disease genes, novel pathways exposed - Example: APECED - AIRE protein - AIRE regulates ectopic expression in thymus - AIRE deficiency - Simplifying the complex genetic background of common diseases - Advantages of isolated populations - Internal isolates: increased genetic homogeneity - Lactose intolerance - Adult type hypolactasia - Severe coronary heart disease - Familial combined hyperlipidemia, FCHL - USF1: a transcription factor - Effect of genetic association on target cells, coronary wall and impact in population - Population based cohorts in Finland - Global effort is needed.…”
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Use of isolated populations in disease gene identification

Table of Contents: “…Contents: Disease mutations in Finland - Molecular background of Finnish disease heritage - Finnish disease genes, novel pathways exposed - Example: APECED - AIRE protein - AIRE regulates ectopic expression in thymus - AIRE deficiency - Simplifying the complex genetic background of common diseases - Advantages of isolated populations - Internal isolates: increased genetic homogeneity - Lactose intolerance - Adult type hypolactasia - Severe coronary heart disease - Familial combined hyperlipidemia, FCHL - USF1: a transcription factor - Effect of genetic association on target cells, coronary wall and impact in population - Population based cohorts in Finland - Global effort is needed.…”
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Genome-wide mapping of estrogen receptor binding sites and activity

Table of Contents: “…Contents: Estrogen receptor-chromatin interactions -- Cis-regulatory elements that function from a distance -- ER binding sites and gene transcription -- Co-operating transcription factors -- Pioneer factors that maintain ER-chromatin interactions.…”
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Genome-wide mapping of estrogen receptor binding sites and activity /

Table of Contents: “…Contents: Estrogen receptor-chromatin interactions -- Cis-regulatory elements that function from a distance -- ER binding sites and gene transcription -- Co-operating transcription factors -- Pioneer factors that maintain ER-chromatin interactions.…”
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Genome-wide mapping of estrogen receptor binding sites and activity /

Table of Contents: “…Contents: Estrogen receptor-chromatin interactions -- Cis-regulatory elements that function from a distance -- ER binding sites and gene transcription -- Co-operating transcription factors -- Pioneer factors that maintain ER-chromatin interactions.…”
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General factors affecting drug metabolism effect of physiological factors and disease, part 2 of 2 /

Table of Contents: “…Contents: Effect of physiological and pathophysiological conditions on drug-metabolizing enzymes (DMEs) -- Role of growth hormones and transcription factors in sex-dependent expression -- Drug clearance and age -- Developmental regulation -- Impact of infection and inflammatory disease on DME expression -- Clinical consequences.…”
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General factors affecting drug metabolism effect of physiological factors and disease, part 2 of 2 /

Table of Contents: “…Contents: Effect of physiological and pathophysiological conditions on drug-metabolizing enzymes (DMEs) -- Role of growth hormones and transcription factors in sex-dependent expression -- Drug clearance and age -- Developmental regulation -- Impact of infection and inflammatory disease on DME expression -- Clinical consequences.…”
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General factors affecting drug metabolism effect of physiological factors and disease, part 2 of 2 /

Table of Contents: “…Contents: Effect of physiological and pathophysiological conditions on drug-metabolizing enzymes (DMEs) -- Role of growth hormones and transcription factors in sex-dependent expression -- Drug clearance and age -- Developmental regulation -- Impact of infection and inflammatory disease on DME expression -- Clinical consequences.…”
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Plant genes, genomes, and genetics / by Grotewold, Erich, Chappell, Joseph, Kellogg, Elizabeth Anne

Table of Contents: “…The plant genetic material -- The genome landscape : plastic and dynamic -- Transposable elements -- Centromeres, telomeres and chromatin -- Organelle genomes -- RNA -- The plant RNA polymerases -- Making mRNAs : control of transcription by RNP-II -- Controlling nuclear transcription -- Control of transcription factor function -- Small RNAs -- Chromatin and gene expression -- RNA processing and transport -- Fate of RNA -- Translation of RNA -- Protein folding and transport -- Protein degradation.…”
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Nuclear control of respiratory chain expression by transcriptional activators and coactivators

Table of Contents: “…Contents: Contribution of nuclear and mitochondrial genomes to respiratory chain expression -- Genomic origin of respiratory chain subunits -- Cytochrome c as a model for respiratory gene expression -- DNA binding and transcriptional properties of nuclear respiratory factors (NRF-1 and NRF-2) -- Identification and characterization of NRF target genes -- Phenotypes associated with a targeted disruption of NRF-1 in mice -- NRF control of mitochondrial transcription factor expression -- The PGC-1 family -- PRC functional interactions with NRF-1 and CREB -- Cytochrome c promoter occupancy by PRC during the transition from quiescence to proliferative growth -- Potential role for PRC in integrating mitochondrial functions with cell growth.…”
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Nuclear control of respiratory chain expression by transcriptional activators and coactivators

Table of Contents: “…Contents: Contribution of nuclear and mitochondrial genomes to respiratory chain expression -- Genomic origin of respiratory chain subunits -- Cytochrome c as a model for respiratory gene expression -- DNA binding and transcriptional properties of nuclear respiratory factors (NRF-1 and NRF-2) -- Identification and characterization of NRF target genes -- Phenotypes associated with a targeted disruption of NRF-1 in mice -- NRF control of mitochondrial transcription factor expression -- The PGC-1 family -- PRC functional interactions with NRF-1 and CREB -- Cytochrome c promoter occupancy by PRC during the transition from quiescence to proliferative growth -- Potential role for PRC in integrating mitochondrial functions with cell growth.…”
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Nuclear control of respiratory chain expression by transcriptional activators and coactivators

Table of Contents: “…Contents: Contribution of nuclear and mitochondrial genomes to respiratory chain expression -- Genomic origin of respiratory chain subunits -- Cytochrome c as a model for respiratory gene expression -- DNA binding and transcriptional properties of nuclear respiratory factors (NRF-1 and NRF-2) -- Identification and characterization of NRF target genes -- Phenotypes associated with a targeted disruption of NRF-1 in mice -- NRF control of mitochondrial transcription factor expression -- The PGC-1 family -- PRC functional interactions with NRF-1 and CREB -- Cytochrome c promoter occupancy by PRC during the transition from quiescence to proliferative growth -- Potential role for PRC in integrating mitochondrial functions with cell growth.…”
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Regulators of ovarian functions by Sirotkin, Alexander V.

Table of Contents: “…The ovary and ovarian cycle -- Oocytes and their maturation -- Extracellular regulators of ovarian functions -- Protein kinases in control of ovarian functions -- Transcription factors in control of ovarian functions -- RNA interference in control of ovarian functions -- Regulation of oocyte maturation -- Physiological and artifical regulation of ovarian cycle.…”
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Nuclear receptors transcriptional functions /

Table of Contents: “…Contents: Introduction to transcription factors -- Nuclear receptors as ligand-dependent transcription factors -- Classes of nuclear receptor -- Nuclear receptor ligands: agonists and antagonists -- Nuclear receptor phylogeny -- Nuclear receptor isoforms -- The nuclear receptor DNA-binding domain -- Hormone response elements -- The nuclear receptor ligand-binding domain -- Nuclear receptor mechanism -- Subcellular localization of nuclear receptors -- The effect of ligand binding -- Nuclear receptor coregulators -- Initial discoveries of coregulators -- The SRC/p160 coregulator family -- Nuclear receptor-coregulator interaction motifs -- Histone acetylation and chromatin structure -- The Nuclear Receptor Signaling Atlas (NURSA) -- Chromatin immunoprecipitation as a tool in nuclear receptor mechanism -- Functional differences between type I and type II nuclear receptors -- The coregulator exchange -- DNA-binding independent functions -- Transrepression -- The role of kinases.…”
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Nuclear receptors transcriptional functions /

Table of Contents: “…Contents: Introduction to transcription factors -- Nuclear receptors as ligand-dependent transcription factors -- Classes of nuclear receptor -- Nuclear receptor ligands: agonists and antagonists -- Nuclear receptor phylogeny -- Nuclear receptor isoforms -- The nuclear receptor DNA-binding domain -- Hormone response elements -- The nuclear receptor ligand-binding domain -- Nuclear receptor mechanism -- Subcellular localization of nuclear receptors -- The effect of ligand binding -- Nuclear receptor coregulators -- Initial discoveries of coregulators -- The SRC/p160 coregulator family -- Nuclear receptor-coregulator interaction motifs -- Histone acetylation and chromatin structure -- The Nuclear Receptor Signaling Atlas (NURSA) -- Chromatin immunoprecipitation as a tool in nuclear receptor mechanism -- Functional differences between type I and type II nuclear receptors -- The coregulator exchange -- DNA-binding independent functions -- Transrepression -- The role of kinases.…”
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