Search Results - "proteins"

Alternative splicing and calcium ion channel diversity

Table of Contents: “…Contents: Calcium -- Cellular Functions -- Voltage-gated calcium channels -- Functional and structural diversity -- Multiple subunits -- Multiple genes -- Gating, permeation, modulation -- Alternative pre-mRNA splicing -- cell-specific splicing factors -- CaV2.2 N-type channel -- Splicing and G protein inhibition.…”
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Motor neurone disease molecular basis /

Table of Contents: “…Contents: Models of MND pathogenesis -- Current understanding on genetic basis of MND -- Animal and cellular models -- Pathways of motor neurone vulnerability -- Abnormal protein handling -- Mitochondrial dysfunction -- Abnormalities in axonal transport and apoptosis -- Current limitations in treatment -- Role of genetic research in identifying biological basis -- Future directions and developing biomarkers.…”
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Understanding hormones mechanisms of androgen receptor function in reproduction and cancer /

Table of Contents: “…Contents: Mechanisms of androgen action -- Biological basis for androgen potency -- Androgen receptor FXXLF motif and N/C interaction -- Androgen receptor coactivator melanoma antigen gene protein-11 -- Androgen receptor mutations in the androgen insensitivity syndrome and prostate cancer -- Mechanisms of prostate cancer progression to castration-recurrent disease.…”
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The bioinformatics of microarrays

Table of Contents: “…Contents: Overview of microarrays -- Clustering microarray data -- Clustering distance measures -- Clustering methods -- Classification methods -- Gene set enrichment testing -- Data mining, pathway, and protein interaction software -- Literature mining tools -- Examples of bioinformatics software tools -- Sharing your data: MIAME -- Microarray databases -- Integration of data.…”
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Huntington's disease and HD-like disorders

Table of Contents: “…Contents: Huntington's disease -- Huntington's disease like disorders -- Chorea -- Anticipation -- Pathobiology of Huntington's disease -- Huntingtin protein misfolding -- Aggregation -- Ubiquitous expression including in peripheral tissues -- Juvenile Huntington's disease/Westphal variant -- Psychiatric, behavioural and cognitive symptomatology -- HD phenocopies -- C9Orf72 and SCA17.…”
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Voltage-dependent gating of ion channels

Table of Contents: “…Contents: Voltage-dependent ion channels -- Critical to proper nerve and muscle function -- Voltage sensitivity is mediated by positively charged segments of the protein -- These voltage sensors move outward with depolarization to trigger channel opening -- The return of one sensor to the resting positions closes the channel -- Hypothesized mechanisms of voltage sensor movement are detailed.…”
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Alternative splicing and calcium ion channel diversity

Table of Contents: “…Contents: Calcium -- Cellular Functions -- Voltage-gated calcium channels -- Functional and structural diversity -- Multiple subunits -- Multiple genes -- Gating, permeation, modulation -- Alternative pre-mRNA splicing -- cell-specific splicing factors -- CaV2.2 N-type channel -- Splicing and G protein inhibition.…”
Get full text
Series

Motor neurone disease molecular basis /

Table of Contents: “…Contents: Models of MND pathogenesis -- Current understanding on genetic basis of MND -- Animal and cellular models -- Pathways of motor neurone vulnerability -- Abnormal protein handling -- Mitochondrial dysfunction -- Abnormalities in axonal transport and apoptosis -- Current limitations in treatment -- Role of genetic research in identifying biological basis -- Future directions and developing biomarkers.…”
Get full text
Series

Understanding hormones mechanisms of androgen receptor function in reproduction and cancer /

Table of Contents: “…Contents: Mechanisms of androgen action -- Biological basis for androgen potency -- Androgen receptor FXXLF motif and N/C interaction -- Androgen receptor coactivator melanoma antigen gene protein-11 -- Androgen receptor mutations in the androgen insensitivity syndrome and prostate cancer -- Mechanisms of prostate cancer progression to castration-recurrent disease.…”
Get full text
Series

The bioinformatics of microarrays

Table of Contents: “…Contents: Overview of microarrays -- Clustering microarray data -- Clustering distance measures -- Clustering methods -- Classification methods -- Gene set enrichment testing -- Data mining, pathway, and protein interaction software -- Literature mining tools -- Examples of bioinformatics software tools -- Sharing your data: MIAME -- Microarray databases -- Integration of data.…”
Get full text
Series

Motor neurone disease molecular basis /

Table of Contents: “…Contents: Models of MND pathogenesis -- Current understanding on genetic basis of MND -- Animal and cellular models -- Pathways of motor neurone vulnerability -- Abnormal protein handling -- Mitochondrial dysfunction -- Abnormalities in axonal transport and apoptosis -- Current limitations in treatment -- Role of genetic research in identifying biological basis -- Future directions and developing biomarkers.…”
Get full text
Series

Understanding hormones mechanisms of androgen receptor function in reproduction and cancer /

Table of Contents: “…Contents: Mechanisms of androgen action -- Biological basis for androgen potency -- Androgen receptor FXXLF motif and N/C interaction -- Androgen receptor coactivator melanoma antigen gene protein-11 -- Androgen receptor mutations in the androgen insensitivity syndrome and prostate cancer -- Mechanisms of prostate cancer progression to castration-recurrent disease.…”
Get full text
Series

The bioinformatics of microarrays

Table of Contents: “…Contents: Overview of microarrays -- Clustering microarray data -- Clustering distance measures -- Clustering methods -- Classification methods -- Gene set enrichment testing -- Data mining, pathway, and protein interaction software -- Literature mining tools -- Examples of bioinformatics software tools -- Sharing your data: MIAME -- Microarray databases -- Integration of data.…”
Get full text
Series

Alternative splicing and calcium ion channel diversity

Table of Contents: “…Contents: Calcium -- Cellular Functions -- Voltage-gated calcium channels -- Functional and structural diversity -- Multiple subunits -- Multiple genes -- Gating, permeation, modulation -- Alternative pre-mRNA splicing -- cell-specific splicing factors -- CaV2.2 N-type channel -- Splicing and G protein inhibition.…”
Get full text
Series

Voltage-dependent gating of ion channels

Table of Contents: “…Contents: Voltage-dependent ion channels -- Critical to proper nerve and muscle function -- Voltage sensitivity is mediated by positively charged segments of the protein -- These voltage sensors move outward with depolarization to trigger channel opening -- The return of one sensor to the resting positions closes the channel -- Hypothesized mechanisms of voltage sensor movement are detailed.…”
Get full text
Series

Huntington's disease and HD-like disorders

Table of Contents: “…Contents: Huntington's disease -- Huntington's disease like disorders -- Chorea -- Anticipation -- Pathobiology of Huntington's disease -- Huntingtin protein misfolding -- Aggregation -- Ubiquitous expression including in peripheral tissues -- Juvenile Huntington's disease/Westphal variant -- Psychiatric, behavioural and cognitive symptomatology -- HD phenocopies -- C9Orf72 and SCA17.…”
Get full text
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Poisons physiologically active substances / by Zotov, S. B. (Stanislav Borisovich)

Table of Contents: “…Poisons in mythology -- Poisons in ancient world -- Poisons in middle ages -- Development of the chemistry of physiologically active substances (PhAS) in the nineteenth and twentieth centuries -- Poisons and elementary bases of toxicology -- Muscarine -- Curare -- Strongest nonprotein poisons -- Toxins of protein and similar structure -- Chemical warfare agents -- Harmful substances in the environment -- Natural and synthetic PhAS.…”
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Vaccines in the modern world

Table of Contents: “…-- Vaccine composition -- Vaccines in common use -- Type of immune response induced by vaccination -- Impact on disease incidence -- Smallpox: the first vaccine -- Vaccines against polio and meningitis -- What is a conjugated vaccine -- Reverse vaccinology -- Novartis MenB protein vaccine -- Vaccines can now be based on DNA.…”
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Selenium and male fertility

Table of Contents: “…Contents: Selenium in nutrition -- Selenocysteine as the 21st aminoacid -- Eukaryotic selenocysteine-containing proteins -- GPx4 and the Sec-glutathione peroxidases -- The redox chemistry of GPx4 and spermatogenesis -- Selenium and male fertility -- Whole body KO of GPx4 -- Selenoproteins involved in spermatogenesis -- Spermatozoa GPx4 activity as a biomarker of fertility.…”
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Vaccines in the modern world

Table of Contents: “…-- Vaccine composition -- Vaccines in common use -- Type of immune response induced by vaccination -- Impact on disease incidence -- Smallpox: the first vaccine -- Vaccines against polio and meningitis -- What is a conjugated vaccine -- Reverse vaccinology -- Novartis MenB protein vaccine -- Vaccines can now be based on DNA.…”
Get full text
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