Search Results - "proteins"

The E2F family and transcriptional control of the mammalian cell cycle

Table of Contents: “…Contents: Complex and diverse roles of E2F family members -- Interaction with tumour repressor proteins -- Interaction with chromatin modifying enzymes -- Study using microarray technology and chromatin immunoprecipitation -- Novel features of cell cycle dependent transcription -- Roles in regulating G1-to-S transition, mitosis, differentiation, and apoptosis.…”
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Spatial and temporal aspects of cellular calcium signals 'elementary' signals and waves /

Table of Contents: “…Contents: Calcium as a life and death cellular messenger -- Sequestration and liberation of calcium from the endoplasmic reticulum -- Calcium release through inositol trisphosphate receptors and modulation by calcium -- Optical techniques to visualize and stimulate intracellular calcium signals -- 'Elementary' calcium signals through single channels and clusters of channels -- Generation of periodic calcium waves by stochastic elementary events -- Modulation of calcium signals by calcium binding proteins -- The hierarchical organization of cellular calcium signals.…”
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Adipose tissue metabolism and obesity

Table of Contents: “…Contents: Experimental approaches for study of adipose tissue biology -- Lipoprotein lipase and triacylglycerol hydrolysis -- Fatty acid uptake by fat cells -- Triacylglycerol synthesis -- Lipid droplets -- Adipocyte lipases -- Lipid droplet proteins -- Catecholamine-induced lipolysis -- Catecholamine and insulin signalling pathways -- Natriuretic peptides -- Atrial natriuretic peptide and lipolysis -- Lipid mobilization in lean and obese patients -- In situ microdialysis and lipolysis exploration -- Exercise-induced lipid mobilization in lean and obese -- Role of catecholamines -- Alpha2-adrenergic responsiveness and obesity -- Natriuretic peptides and lipid mobilization.…”
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The kinetochore as a target for the development of mitosis specific anti-cancer drugs

Table of Contents: “…Contents: Mitosis is critical for cells to proliferate and is a major target of current anti-cancer drugs such as paclitaxel and vinca alkaloids -- Characterization of proteins essential for mitosis has made available the opportunity to develop new anti-mitotic agents -- Expanding the number of anti-cancer drug targets should significantly improve the response of tumors to chemotherapies.…”
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AMPA-receptors and fast synaptic transmission in the brain

Table of Contents: “…Contents: The fast component of excitatory synaptic transmission in the brain mediated by AMPARs -- Functionally distinct AMPAR subtypes are involved in transmission (importance of topology) -- How AMPAR diversity shapes transmission (implications of differential distribution and plasticity) -- How AMPAR structure affects its behaviour and properties -- Role of auxiliary AMPAR proteins (stargazin) in controlling AMPAR properties and diversity.…”
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Ca2+, the endoplasmic reticulum and cardiac pathology

Table of Contents: “…Contents: Molecular studies on the endoplasmic reticulum (ER) function and ER associated chaperones including calreticulin -- ER-associated functions are crucial in cardiac physiology and pathology -ER stress responses -- ER calcium buffering proteins impact many cardiac functions including cardiogenesis, ischemia and reperfusion, cardiomyopathies and heart failure.…”
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Spatial and temporal aspects of cellular calcium signals 'elementary' signals and waves /

Table of Contents: “…Contents: Calcium as a life and death cellular messenger -- Sequestration and liberation of calcium from the endoplasmic reticulum -- Calcium release through inositol trisphosphate receptors and modulation by calcium -- Optical techniques to visualize and stimulate intracellular calcium signals -- 'Elementary' calcium signals through single channels and clusters of channels -- Generation of periodic calcium waves by stochastic elementary events -- Modulation of calcium signals by calcium binding proteins -- The hierarchical organization of cellular calcium signals.…”
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Features of mammalian CNS barrier systems

Table of Contents: “…Contents: Choroid plexus -- Formation of CSF -- Permeability of blood -- CSF barrier vs. blood-brain barrier -- Choroidal secretion of peptides, growth factors and regulatory proteins -- Homeostasis and bulk flow of extracellular fluid in the CNS -- Impact of CSF dynamics on brain metabolism -- Disrupted transport at the blood-CSF interface in hyperthermia, ischemia and Alzheimer's disease -- Reduced CSF reabsorption in aging, hydrocephalus and dementia.…”
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Adipose tissue metabolism and obesity

Table of Contents: “…Contents: Experimental approaches for study of adipose tissue biology -- Lipoprotein lipase and triacylglycerol hydrolysis -- Fatty acid uptake by fat cells -- Triacylglycerol synthesis -- Lipid droplets -- Adipocyte lipases -- Lipid droplet proteins -- Catecholamine-induced lipolysis -- Catecholamine and insulin signalling pathways -- Natriuretic peptides -- Atrial natriuretic peptide and lipolysis -- Lipid mobilization in lean and obese patients -- In situ microdialysis and lipolysis exploration -- Exercise-induced lipid mobilization in lean and obese -- Role of catecholamines -- Alpha2-adrenergic responsiveness and obesity -- Natriuretic peptides and lipid mobilization.…”
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The kinetochore as a target for the development of mitosis specific anti-cancer drugs

Table of Contents: “…Contents: Mitosis is critical for cells to proliferate and is a major target of current anti-cancer drugs such as paclitaxel and vinca alkaloids -- Characterization of proteins essential for mitosis has made available the opportunity to develop new anti-mitotic agents -- Expanding the number of anti-cancer drug targets should significantly improve the response of tumors to chemotherapies.…”
Get full text
Series

Spatial and temporal aspects of cellular calcium signals 'elementary' signals and waves /

Table of Contents: “…Contents: Calcium as a life and death cellular messenger -- Sequestration and liberation of calcium from the endoplasmic reticulum -- Calcium release through inositol trisphosphate receptors and modulation by calcium -- Optical techniques to visualize and stimulate intracellular calcium signals -- 'Elementary' calcium signals through single channels and clusters of channels -- Generation of periodic calcium waves by stochastic elementary events -- Modulation of calcium signals by calcium binding proteins -- The hierarchical organization of cellular calcium signals.…”
Get full text
Series

Features of mammalian CNS barrier systems

Table of Contents: “…Contents: Choroid plexus -- Formation of CSF -- Permeability of blood -- CSF barrier vs. blood-brain barrier -- Choroidal secretion of peptides, growth factors and regulatory proteins -- Homeostasis and bulk flow of extracellular fluid in the CNS -- Impact of CSF dynamics on brain metabolism -- Disrupted transport at the blood-CSF interface in hyperthermia, ischemia and Alzheimer's disease -- Reduced CSF reabsorption in aging, hydrocephalus and dementia.…”
Get full text
Series

The kinetochore as a target for the development of mitosis specific anti-cancer drugs

Table of Contents: “…Contents: Mitosis is critical for cells to proliferate and is a major target of current anti-cancer drugs such as paclitaxel and vinca alkaloids -- Characterization of proteins essential for mitosis has made available the opportunity to develop new anti-mitotic agents -- Expanding the number of anti-cancer drug targets should significantly improve the response of tumors to chemotherapies.…”
Get full text
Series

Adipose tissue metabolism and obesity

Table of Contents: “…Contents: Experimental approaches for study of adipose tissue biology -- Lipoprotein lipase and triacylglycerol hydrolysis -- Fatty acid uptake by fat cells -- Triacylglycerol synthesis -- Lipid droplets -- Adipocyte lipases -- Lipid droplet proteins -- Catecholamine-induced lipolysis -- Catecholamine and insulin signalling pathways -- Natriuretic peptides -- Atrial natriuretic peptide and lipolysis -- Lipid mobilization in lean and obese patients -- In situ microdialysis and lipolysis exploration -- Exercise-induced lipid mobilization in lean and obese -- Role of catecholamines -- Alpha2-adrenergic responsiveness and obesity -- Natriuretic peptides and lipid mobilization.…”
Get full text
Series

Ca2+, the endoplasmic reticulum and cardiac pathology

Table of Contents: “…Contents: Molecular studies on the endoplasmic reticulum (ER) function and ER associated chaperones including calreticulin -- ER-associated functions are crucial in cardiac physiology and pathology -ER stress responses -- ER calcium buffering proteins impact many cardiac functions including cardiogenesis, ischemia and reperfusion, cardiomyopathies and heart failure.…”
Get full text
Series

AMPA-receptors and fast synaptic transmission in the brain

Table of Contents: “…Contents: The fast component of excitatory synaptic transmission in the brain mediated by AMPARs -- Functionally distinct AMPAR subtypes are involved in transmission (importance of topology) -- How AMPAR diversity shapes transmission (implications of differential distribution and plasticity) -- How AMPAR structure affects its behaviour and properties -- Role of auxiliary AMPAR proteins (stargazin) in controlling AMPAR properties and diversity.…”
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The choroid in aging and disease

Table of Contents: “…Contents: Age-related Macular Degeneration (AMD) -- Drusen -- Atrophy -- Vascular changes -- Proteomics of choroidal thinning -- Fibrosis -- CD34 -- C-reactive protein accumulation -- Complement cascade: Membrane Attack Complex (MAC).…”
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Mechanisms of RNAi a molecular view or Argonaute : the secret life of slicer /

Table of Contents: “…Contents: Impact of RNAi on biology -- Gene silencing -- Mechanism of unravelling -- Understanding the mechanism of RNAi related pathways -- Transcriptional and post-transcriptional gene silencing -- DNA elimination in tetrahymena -- Mechanistic aspects of RNAi -- The argonaute protein.…”
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Structure of cell walls in yeast and other fungi

Table of Contents: “…Contents: Fungal cell walls -- Glycans -- S. cerevisiae -- C. albicans -- Mannose -- Chitin -- Glycan biosynthesis -- Mannoproteins -- GPI-crosslinked proteins -- N. crassa -- Yeast cell wall dynamics -- Cell wall conservation and evolution.…”
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ABO blood groups and SARS-CoV-2 susceptibility

Table of Contents: “…Contents: How blood group can affect susceptibility to viruses -- The initial studies into blood group and COVID-19 susceptibility -- Molecular research in this topic -- The possible involvement of the Rhesus (Rh) protein -- Future steps in this field.…”
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