Search Results - "proteins"

AMPA-receptors and fast synaptic transmission in the brain

Table of Contents: “…Contents: The fast component of excitatory synaptic transmission in the brain mediated by AMPARs -- Functionally distinct AMPAR subtypes are involved in transmission (importance of topology) -- How AMPAR diversity shapes transmission (implications of differential distribution and plasticity) -- How AMPAR structure affects its behaviour and properties -- Role of auxiliary AMPAR proteins (stargazin) in controlling AMPAR properties and diversity.…”
Get full text
Series

An overview of the neuropathology of neurodegenerative diseases

Table of Contents: “…. -- The pathological proteins for each disease are discussed and the types of pathological lesions formed.…”
Get full text
Series

Ca2+, the endoplasmic reticulum and cardiac pathology

Table of Contents: “…Contents: Molecular studies on the endoplasmic reticulum (ER) function and ER associated chaperones including calreticulin -- ER-associated functions are crucial in cardiac physiology and pathology -ER stress responses -- ER calcium buffering proteins impact many cardiac functions including cardiogenesis, ischemia and reperfusion, cardiomyopathies and heart failure.…”
Get full text
Series

Intravenous immunoglobulins myth and reality /

Table of Contents: “…Contents: The use of intravenous immunoglobulins (IVIg) as therapeutic proteins -- Use of IVIg to provide effective treatment for autoimmune thrombocytopenic purpura -- Use of IVIg in a large range of autoimmune or systemic inflammatory diseases -- Increase in worldwide IVIg demand -- Increased evidence showing the efficacy of IVIg -- Mechanisms for the action of IVIg in autoimmune diseases -- Need for classification of the recommendations for use -- Clinical indications for IVIg therapy.…”
Get full text
Series

The endoplasmic reticulum as a calcium gateway in programmed cell death

Table of Contents: “…Contents: Calcium signals: cardiac contraction -- Intracellular calcium signals -- The calcium language of cells -- Cellular sources of calcium -- "Calciosomes": the ER and mitochondria -- Calcium probes -- ER and mitochondria dynamics -- ER calcium signals -- Mitochondrial calcium signals -- Mitochondrial calcium paradox -- The ERmitochondria connection -- Calcium and mitochondrial permeability -- ER calcium load -- Bcl-2 family proteins -- Protective effect of ER depletion -- Bax/Bak ablation -- Apoptosis: the calcium connection.…”
Get full text
Series

Mechanisms of human genetic disease

Table of Contents: “…Contents: Mechanisms of human genetic disorders -- Loss of function effects -- Dominant negative mechanisms -- Increased gene dosage -- Gain of function effects -- Proteins toxicity -- Abnormal gene expression and regulation.…”
Get full text
Series

The E2F family and transcriptional control of the mammalian cell cycle

Table of Contents: “…Contents: Complex and diverse roles of E2F family members -- Interaction with tumour repressor proteins -- Interaction with chromatin modifying enzymes -- Study using microarray technology and chromatin immunoprecipitation -- Novel features of cell cycle dependent transcription -- Roles in regulating G1-to-S transition, mitosis, differentiation, and apoptosis.…”
Get full text
Series

Mitochondrial DNA replication and transcription

Table of Contents: “…Contents: Introduction to the mitochondrial genetic system -- Features of mammalian mitochondrial DNA -- Characteristics of mitochondrial genetics -- Mitochondrial DNA replication: strand-displacement and strand-coupled models -- Proteins involved in mitochondrial DNA replication -- Mitochondrial DNA transcription -- Isolation and mapping of mitochondrial RNA -- Model of transcription and RNA processing -- Regulation of mtDNA expression by thyroid hormones -- Regulation of the mammalian mtDNA expression by mTERF phosphorylation.…”
Get full text
Series

Intravenous immunoglobulins myth and reality /

Table of Contents: “…Contents: The use of intravenous immunoglobulins (IVIg) as therapeutic proteins -- Use of IVIg to provide effective treatment for autoimmune thrombocytopenic purpura -- Use of IVIg in a large range of autoimmune or systemic inflammatory diseases -- Increase in worldwide IVIg demand -- Increased evidence showing the efficacy of IVIg -- Mechanisms for the action of IVIg in autoimmune diseases -- Need for classification of the recommendations for use -- Clinical indications for IVIg therapy.…”
Get full text
Series

The endoplasmic reticulum as a calcium gateway in programmed cell death

Table of Contents: “…Contents: Calcium signals: cardiac contraction -- Intracellular calcium signals -- The calcium language of cells -- Cellular sources of calcium -- "Calciosomes": the ER and mitochondria -- Calcium probes -- ER and mitochondria dynamics -- ER calcium signals -- Mitochondrial calcium signals -- Mitochondrial calcium paradox -- The ERmitochondria connection -- Calcium and mitochondrial permeability -- ER calcium load -- Bcl-2 family proteins -- Protective effect of ER depletion -- Bax/Bak ablation -- Apoptosis: the calcium connection.…”
Get full text
Series

Historical introduction to human diversity I

Table of Contents: “…Contents: The inherited nature of diversity in humans -- Person to person variability -- Human biochemical genetics -- Inborn errors of metabolism -- Alkaptonuria -- Phenylketonuria -- Recessive inheritance -- Abundant and structural proteins -- Sickle cell anaemia -- Pharmacogenetics and pharmacogenomics -- G6PD deficiency.…”
Get full text
Series

The E2F family and transcriptional control of the mammalian cell cycle

Table of Contents: “…Contents: Complex and diverse roles of E2F family members -- Interaction with tumour repressor proteins -- Interaction with chromatin modifying enzymes -- Study using microarray technology and chromatin immunoprecipitation -- Novel features of cell cycle dependent transcription -- Roles in regulating G1-to-S transition, mitosis, differentiation, and apoptosis.…”
Get full text
Series

Mitochondrial DNA replication and transcription

Table of Contents: “…Contents: Introduction to the mitochondrial genetic system -- Features of mammalian mitochondrial DNA -- Characteristics of mitochondrial genetics -- Mitochondrial DNA replication: strand-displacement and strand-coupled models -- Proteins involved in mitochondrial DNA replication -- Mitochondrial DNA transcription -- Isolation and mapping of mitochondrial RNA -- Model of transcription and RNA processing -- Regulation of mtDNA expression by thyroid hormones -- Regulation of the mammalian mtDNA expression by mTERF phosphorylation.…”
Get full text
Series

Intravenous immunoglobulins myth and reality /

Table of Contents: “…Contents: The use of intravenous immunoglobulins (IVIg) as therapeutic proteins -- Use of IVIg to provide effective treatment for autoimmune thrombocytopenic purpura -- Use of IVIg in a large range of autoimmune or systemic inflammatory diseases -- Increase in worldwide IVIg demand -- Increased evidence showing the efficacy of IVIg -- Mechanisms for the action of IVIg in autoimmune diseases -- Need for classification of the recommendations for use -- Clinical indications for IVIg therapy.…”
Get full text
Series

The endoplasmic reticulum as a calcium gateway in programmed cell death

Table of Contents: “…Contents: Calcium signals: cardiac contraction -- Intracellular calcium signals -- The calcium language of cells -- Cellular sources of calcium -- "Calciosomes": the ER and mitochondria -- Calcium probes -- ER and mitochondria dynamics -- ER calcium signals -- Mitochondrial calcium signals -- Mitochondrial calcium paradox -- The ERmitochondria connection -- Calcium and mitochondrial permeability -- ER calcium load -- Bcl-2 family proteins -- Protective effect of ER depletion -- Bax/Bak ablation -- Apoptosis: the calcium connection.…”
Get full text
Series

Historical introduction to human diversity I

Table of Contents: “…Contents: The inherited nature of diversity in humans -- Person to person variability -- Human biochemical genetics -- Inborn errors of metabolism -- Alkaptonuria -- Phenylketonuria -- Recessive inheritance -- Abundant and structural proteins -- Sickle cell anaemia -- Pharmacogenetics and pharmacogenomics -- G6PD deficiency.…”
Get full text
Series

Mechanisms of human genetic disease

Table of Contents: “…Contents: Mechanisms of human genetic disorders -- Loss of function effects -- Dominant negative mechanisms -- Increased gene dosage -- Gain of function effects -- Proteins toxicity -- Abnormal gene expression and regulation.…”
Get full text
Series

Detection and quantification of antibodies to biopharmaceuticals practical and applied considerations /

Table of Contents: “…O'Neill -- Immunogenicity of therapeutic proteins : a regulatory perspective / Susan Kirshner -- Guidance on immunogenicity assessment of biologically-derived therapeutic proteins : an European perspective / Meenu Wadhwa and Robin Thorpe -- Japanese regulatory perspective on immunogenicity / Takao Hayakawa and Akiko Ishii -- Enzyme immunoassays and radioimmune assays for quantification of anti-TNF biopharmaceuticals and anti-drug antibodies / Klaus Bendtzen and Morten Svenson -- Confirmatory immunogenicity assays / Eric Wakshull and Daniel Coleman -- The use of pharmacodynamics as a surrogate marker for the detection of anti-drug neutralizing antibodies / Florian Deisenhammer -- Cell-based assays for the detection of neutralizing antibodies to interferon beta (IFN-?) …”
An electronic book accessible through the World Wide Web; click to view

Principles of animal nutrition / by Wu, Guoyao, 1962-

Table of Contents: “…chapter 1 Physiological and Biochemical Bases of Animal Nutrition -- chapter 2 Chemistry of Carbohydrates -- chapter 3 Chemistry of Lipids -- chapter 4 Chemistry of Protein and Amino Acids -- chapter 5 Nutrition and Metabolism of Carbohydrates -- chapter 6 Nutrition and Metabolism of Lipids -- chapter 7 Nutrition and Metabolism of Protein and Amino Acids -- chapter 8 Energy Metabolism -- chapter 9 Nutrition and Metabolism of Vitamins -- chapter 10 Nutrition and Metabolism of Minerals -- chapter 11 Nutritional Requirements for Maintenance and Production -- chapter 12 Regulation of Food Intake by Animals -- chapter 13 Feed Additives.…”
Click here to view.

Molecular plant immunity

Table of Contents: “…Takken 2.1 Introduction 2.2 Building blocks of NB-LRRs; classification and structural features of subdomains 2.3 Putting the parts together: combining the domains to build a signalling competent NB-LRR protein 2.4 Stabilization and accumulation of NB-LRR proteins: their maturation and stabilisation 2.5 Pathogen recognition, how are effectors detected by NB-LRRs? …”
An electronic book accessible through the World Wide Web; click to view