Search Results - "proteins"

Ubiquitination and Alzheimer related disorders new insights and possible therapeutic approaches! /

Table of Contents: “…Contents: Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin and the ubiquitin pathway of intracellular proteolysis -- Ubiquitin immunocytochemistry in understanding chronic neurodegenerative disease -- Ubiquitin and the discovery of dementia with Lewy bodies -- Importance of ubiquitin for normal brain functions -- Ubiquitin and Parkinson's disease -- Intraneuronal protein aggregation and neurodegenerative disease -- Experimental demonstration of generic gene expression changes in response to protein aggregates -- Expression of the mitogen activated protein kinase (MEK5) -- ERK5 kinase module in Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin-p62-MEK5/ERK5 pathway of neuronal survival in Alzheimer related disorders -- Diagnostic and therapeutic importance of ubiquitin/kinase mediated neuronal survival and anti-apoptotic pathways.…”
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Genetic basis of neurological disease

Table of Contents: “…Contents: Neurogenetics -- Allele frequency vs. effect size -- Parkinson's disease (PD) -- PINK1: genetic discovery to protein expression -- Pink1 and mitochondrial abnormalities -- In vivo interaction between PINK1 and Parkin -- Parkinsonian proteins and mitophagy -- Mitochondrial dysfunction -- Protein aggregation -- Ceramide metabolism and PD -- Lysosomal pathway and PD -- Complex trait genetics -- Linkage disequilibrium blocks -- Identifying common genetic factors -- Genetic risk factors & odds of finding variants -- First genome-wide association study for PD -- Parkinson's disease molecular pathways -- Replicate meta-analysis -- The major neurological diseases -- Caveats to consider in GWAS -- The ENCODE study -- Trinucleotide repeats and related disorders -- The impact of next generation sequencing.…”
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Ubiquitination and Alzheimer related disorders new insights and possible therapeutic approaches! /

Table of Contents: “…Contents: Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin and the ubiquitin pathway of intracellular proteolysis -- Ubiquitin immunocytochemistry in understanding chronic neurodegenerative disease -- Ubiquitin and the discovery of dementia with Lewy bodies -- Importance of ubiquitin for normal brain functions -- Ubiquitin and Parkinson's disease -- Intraneuronal protein aggregation and neurodegenerative disease -- Experimental demonstration of generic gene expression changes in response to protein aggregates -- Expression of the mitogen activated protein kinase (MEK5) -- ERK5 kinase module in Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin-p62-MEK5/ERK5 pathway of neuronal survival in Alzheimer related disorders -- Diagnostic and therapeutic importance of ubiquitin/kinase mediated neuronal survival and anti-apoptotic pathways.…”
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Ubiquitination and Alzheimer related disorders new insights and possible therapeutic approaches! /

Table of Contents: “…Contents: Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin and the ubiquitin pathway of intracellular proteolysis -- Ubiquitin immunocytochemistry in understanding chronic neurodegenerative disease -- Ubiquitin and the discovery of dementia with Lewy bodies -- Importance of ubiquitin for normal brain functions -- Ubiquitin and Parkinson's disease -- Intraneuronal protein aggregation and neurodegenerative disease -- Experimental demonstration of generic gene expression changes in response to protein aggregates -- Expression of the mitogen activated protein kinase (MEK5) -- ERK5 kinase module in Alzheimer's disease and dementia with Lewy bodies -- Ubiquitin-p62-MEK5/ERK5 pathway of neuronal survival in Alzheimer related disorders -- Diagnostic and therapeutic importance of ubiquitin/kinase mediated neuronal survival and anti-apoptotic pathways.…”
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Genetic basis of neurological disease

Table of Contents: “…Contents: Neurogenetics -- Allele frequency vs. effect size -- Parkinson's disease (PD) -- PINK1: genetic discovery to protein expression -- Pink1 and mitochondrial abnormalities -- In vivo interaction between PINK1 and Parkin -- Parkinsonian proteins and mitophagy -- Mitochondrial dysfunction -- Protein aggregation -- Ceramide metabolism and PD -- Lysosomal pathway and PD -- Complex trait genetics -- Linkage disequilibrium blocks -- Identifying common genetic factors -- Genetic risk factors & odds of finding variants -- First genome-wide association study for PD -- Parkinson's disease molecular pathways -- Replicate meta-analysis -- The major neurological diseases -- Caveats to consider in GWAS -- The ENCODE study -- Trinucleotide repeats and related disorders -- The impact of next generation sequencing.…”
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Microbial recognition and the immune response

Table of Contents: “…-- Overview of innate immunity -- Cell signaling PRMs -- Toll-like receptors -- Shigella flexneri -- NLRs are related to plant R proteins involved in disease resistance -- NLRs: detectors of MAMPs and danger signals -- Proposed mechanism for Nod protein activation by a MAMP -- Alerting the cell: Nod1 activates NFkB -- Critical role of Nod1 in infected intestinal epithelial cells -- Proposed mechanism for NLRP protein activation by a DAMP -- The inflammasomes -- How do innate immune signals translate into adaptive immune responses? …”
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Gene family targeted molecular design

Table of Contents: “…Drug discoveries by gene family / Karen E. Lackey -- G-protein coupled receptors / Stephen L. Garland and Tom D. …”
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The genetics of frontotemporal dementia

Table of Contents: “…Contents: Overall characteristics of FTD -- Genes involved in frontotemporal dementia -- Pathology of frontotemporal dementia -- FTDP-17: 3R and 4R-tauopathies -- FTLD-TDP subtypes -- MAPT as the gene for FTD with tangles -- The microtubule associated protein tau -- Mutations affecting tau protein in FTD -- PGRN mutations as a cause for FTD -- A major locus for FTD and ALS on chromosome 9 -- Chromosome 3 dementia -- Making sense of these genes.…”
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The genetics of frontotemporal dementia

Table of Contents: “…Contents: Overall characteristics of FTD -- Genes involved in frontotemporal dementia -- Pathology of frontotemporal dementia -- FTDP-17: 3R and 4R-tauopathies -- FTLD-TDP subtypes -- MAPT as the gene for FTD with tangles -- The microtubule associated protein tau -- Mutations affecting tau protein in FTD -- PGRN mutations as a cause for FTD -- A major locus for FTD and ALS on chromosome 9 -- Chromosome 3 dementia -- Making sense of these genes.…”
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The genetics of frontotemporal dementia

Table of Contents: “…Contents: Overall characteristics of FTD -- Genes involved in frontotemporal dementia -- Pathology of frontotemporal dementia -- FTDP-17: 3R and 4R-tauopathies -- FTLD-TDP subtypes -- MAPT as the gene for FTD with tangles -- The microtubule associated protein tau -- Mutations affecting tau protein in FTD -- PGRN mutations as a cause for FTD -- A major locus for FTD and ALS on chromosome 9 -- Chromosome 3 dementia -- Making sense of these genes.…”
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Evolutionary genomics and systems biology

Table of Contents: “…Pollock -- The evolution of protein material costs / Jason G. Bragg & Andreas Wagner -- Protein domains as evolutionary units / Andrew D. …”
An electronic book accessible through the World Wide Web; click to view

Preimplantation embryo development

Table of Contents: “…Contents: Preimplantation embryo development -- Expression of transcripts and proteins during preimplantation development -- Preimplantation embryo metabolism -- Formation of the morula and blastocyst.…”
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Preimplantation embryo development

Table of Contents: “…Contents: Preimplantation embryo development -- Expression of transcripts and proteins during preimplantation development -- Preimplantation embryo metabolism -- Formation of the morula and blastocyst.…”
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Coupling transcription, RNA processing and RNA export

Table of Contents: “…Contents: Mechanistic coupling of RNA processing, export and transcription -- Current evidence supporting coupling mechanisms -- Role of the RNA polymerase II CTD -- Competition during transcription between RNA binding proteins -- Future challenges and directions.…”
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Mechanisms of mitochondrial fusion and fission

Table of Contents: “…Contents: Mitochondrial ultrastructure -- Mitochondrial organization in the cytosol -- Mitochondria-shaping proteins -- Dynamins and the dynamin superfamily -- Control of mitochondrial shape in yeast -- Control of mitochondrial morphology in mammals -- Mitochondrial fusion and the transmission of mitochondrial DNA -- Changes in mitochondrial ultrastructure during apoptosis -- Mitochondrial fragmentation during apoptosis -- Cristae remodeling and OPA1.…”
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Chloroplast genetic engineering

Table of Contents: “…Contents: Advantages, concepts and methodology -- Maternal inheritance and cytoplasmic male sterility -- Agronomic traits to confer insect, herbicide, disease resistance, drought and salt tolerance and phytoremediation -- Transformed crop species -- Production and functional evaluation of human blood proteins (interferon) and vaccines (anthrax) -- Mechanism of oral delivery and protection against insulitis in non-obese diabetic mice -- Crop chloroplast genomics.…”
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DNA processing in conjugative transfer

Table of Contents: “…Contents: Conjugative plasmids -- Original observation of conjugative transfer -- Description of transfer -- DNA specificity in conjugative transfer -- F transfer as an example -- Roles of F proteins in transfer -- Context dependence of F TraI recognition as regulation.…”
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Regulation of gastrulation in Drosophila

Table of Contents: “…Contents: Events during gastrulation and mesoderm cell invagination -- Cell shape changes -- Genes acting upstream of mesodermal invagination -- Search for genes controlling mesoderm cell shape changes -- The role of cell division -- The importance of apical concentration of cytoskeletal regulators, and proteins mediating their apical concentration.…”
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Biotechnology fundamentals / by Khan, Firdos Alam

Taylor & Francis
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The genetic basis of dystonia

Table of Contents: “…Contents: Dystonia outline and historical summary -- Clinical characteristics, aetiology and classification of dystonia -- Different dystonia phenotypes their related genes and mutations -- Molecular pathogenesis and mechanisms in cellular processes and organelles -- Dystonia proteins in pre- and post-synaptic areas.…”
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