Search Results - "proteins"

The spindle checkpoint

Table of Contents: “…-- Unattached kinetochores -- Lack of tension -- Checkpoint components -- Budding yeast genetic screens -- Microcolony assay -- Localisation of Mad proteins -- Checkpoint proteins are all recruited kinetochores -- Role of kinetochores -- Global signaling -- Identification of Cdc20 as the checkpoint effector -- CdC20-APC -- FRAP -- Mad1/Mad2 complex as a template -- The anaphase promoting complex (APC) -- How is anaphase onset inhibited -- Mad2 and Mad3 bind mitotic APC -- Separase regulation by securin -- Error correction -- Chromosomal passenger proteins -- How to sense a lack of tension? …”
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The spindle checkpoint

Table of Contents: “…-- Unattached kinetochores -- Lack of tension -- Checkpoint components -- Budding yeast genetic screens -- Microcolony assay -- Localisation of Mad proteins -- Checkpoint proteins are all recruited kinetochores -- Role of kinetochores -- Global signaling -- Identification of Cdc20 as the checkpoint effector -- CdC20-APC -- FRAP -- Mad1/Mad2 complex as a template -- The anaphase promoting complex (APC) -- How is anaphase onset inhibited -- Mad2 and Mad3 bind mitotic APC -- Separase regulation by securin -- Error correction -- Chromosomal passenger proteins -- How to sense a lack of tension? …”
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Transcriptional activation

Table of Contents: “…Contents: Transcription by RNA polymerase II -- Mediator complex -- Coactivator proteins -- Communication between DNA-binding proteins and general transcription machinery.…”
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Transcriptional activation

Table of Contents: “…Contents: Transcription by RNA polymerase II -- Mediator complex -- Coactivator proteins -- Communication between DNA-binding proteins and general transcription machinery.…”
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Transcriptional activation

Table of Contents: “…Contents: Transcription by RNA polymerase II -- Mediator complex -- Coactivator proteins -- Communication between DNA-binding proteins and general transcription machinery.…”
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Cell surface glycoproteins on cells of the immune system

Table of Contents: “…Contents: Lymphocyte cell surface -- Membrane proteins -- Identification of interactions -- Protein microarrays -- Monoclonal antibodies -- Recombinant proteins -- Characterization of interactions at a molecular level -- Reaction kinetics -- Protein structure -- Role of engagement -- Role in disease and potential therapies.…”
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Targeting apoptosis pathways in cancer therapy

Table of Contents: “…Contents: Apoptosis in cancer -- Apoptosis signalling pathways -- Death receptor pathway -- Mitochondrial pathway -- Targeting the death receptor pathway -- Bcl-2 family proteins: structure and function -- Targeting Bcl-2 family proteins -- IAPs: structure and function -- Targeting IAPs.…”
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Cell surface glycoproteins on cells of the immune system

Table of Contents: “…Contents: Lymphocyte cell surface -- Membrane proteins -- Identification of interactions -- Protein microarrays -- Monoclonal antibodies -- Recombinant proteins -- Characterization of interactions at a molecular level -- Reaction kinetics -- Protein structure -- Role of engagement -- Role in disease and potential therapies.…”
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Molecular endocrinology by Bolander, Franklyn F.

Table of Contents: “…Classical endocrinology -- Nonclassical endocrinology -- Overview of receptors and transducers -- Kinetics -- Nuclear receptors -- Membrane receptors -- Receptor regulation -- G proteins and cyclic nucleotides -- Calcium, calmodulin, and phospholipids -- Miscellaneous second messengers -- Phosphorylation and other nontranscriptional effects of hormones -- Hormonally regulated transcription factors -- Modifications and conformations of DNA and nuclear proteins -- Posttranscriptional control -- Pathogen-endocrine system interactions -- Molecular bases of endocrinopathies -- Molecular evolution of the endocrine system.…”
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Bioinformatics and molecular evolution by Higgs, Paul G.

Table of Contents: “…The revolution in biological information -- Nucleic acids, proteins, and amino acids -- Molecular evolution and population genetics -- Models of sequence evolution -- Information resources for genes and proteins -- Sequence alignment algorithms -- Searching sequence databases -- Phylogenetic methods -- Patterns in protein families -- Probabilistic methods and machine learning -- Further topics in molecular evolution and phylogenetics -- Genome evolution -- DNA microarrays and the 'omes.…”
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Cell surface glycoproteins on cells of the immune system

Table of Contents: “…Contents: Lymphocyte cell surface -- Membrane proteins -- Identification of interactions -- Protein microarrays -- Monoclonal antibodies -- Recombinant proteins -- Characterization of interactions at a molecular level -- Reaction kinetics -- Protein structure -- Role of engagement -- Role in disease and potential therapies.…”
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The airway smooth muscle in asthma

Table of Contents: “…Contents: Remodelling of the Asthmatic airway -- Airway smooth muscle (ASM) -- increased deposition of matrix proteins -- Asthma increases ASM -- Characteristics of ASM cells in non-asthmatics -- Characteristics of ASM in asthmatics -- ASM produces extracellular matrix (ECM) proteins -- Differences in ECM in asthmatics -- Fibulin-1 in asthma -- Fibulin as a therapeutic target.…”
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Apoptotic pathways in mammals

Table of Contents: “…Contents: Apoptosis and programmed cell death -- Apoptosis: developmental signals, damage or stress, loss of adhesion and oncogenesis -- Caspases: inactive and active -- Death folds -- Inhibitors of apoptosis proteins -- Death receptor (extrinsic) pathway -- Mitochondrial (intrinsic) pathway -- The Bcl-2 family proteins -- Apoptosome -- Activation, repression and de-repression -- Caspase-independent cell death -- Cells die in the absence of caspase activation.…”
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Apoptotic pathways in mammals

Table of Contents: “…Contents: Apoptosis and programmed cell death -- Apoptosis: developmental signals, damage or stress, loss of adhesion and oncogenesis -- Caspases: inactive and active -- Death folds -- Inhibitors of apoptosis proteins -- Death receptor (extrinsic) pathway -- Mitochondrial (intrinsic) pathway -- The Bcl-2 family proteins -- Apoptosome -- Activation, repression and de-repression -- Caspase-independent cell death -- Cells die in the absence of caspase activation.…”
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Targeting apoptosis pathways in cancer therapy

Table of Contents: “…Contents: Apoptosis in cancer -- Apoptosis signalling pathways -- Death receptor pathway -- Mitochondrial pathway -- Targeting the death receptor pathway -- Bcl-2 family proteins: structure and function -- Targeting Bcl-2 family proteins -- IAPs: structure and function -- Targeting IAPs.…”
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Apoptotic pathways in mammals

Table of Contents: “…Contents: Apoptosis and programmed cell death -- Apoptosis: developmental signals, damage or stress, loss of adhesion and oncogenesis -- Caspases: inactive and active -- Death folds -- Inhibitors of apoptosis proteins -- Death receptor (extrinsic) pathway -- Mitochondrial (intrinsic) pathway -- The Bcl-2 family proteins -- Apoptosome -- Activation, repression and de-repression -- Caspase-independent cell death -- Cells die in the absence of caspase activation.…”
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Targeting apoptosis pathways in cancer therapy

Table of Contents: “…Contents: Apoptosis in cancer -- Apoptosis signalling pathways -- Death receptor pathway -- Mitochondrial pathway -- Targeting the death receptor pathway -- Bcl-2 family proteins: structure and function -- Targeting Bcl-2 family proteins -- IAPs: structure and function -- Targeting IAPs.…”
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Food allergy

Table of Contents: “…Westphal -- Predicting the allergenicity of novel proteins in genetically modified organisms / Richard E. …”
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MicroRNA biogenesis

Table of Contents: “…Contents: Definition of microRNA -- Comparison to small interfering RNA -- Mechanism of gene silencing -- Factors in the microRNA pathway -- RNase III proteins and their interacting proteins -- MicroRNA gene structure and transcription -- Drosha and primary microRNA processing -- Exportin 5 and pre-microRNA export -- Dicer and pre-microRNA processing -- RISC assembly and strand selection -- MicroRNA biogenesis in plants -- Experimental tools to investigate microRNA.…”
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Monoclonal antibodies and the ErbB system in human cancer

Table of Contents: “…Contents: ErbB and cancer -- The erbB system of genes and proteins -- How erbB proteins associate to form transforming complexes -- How monoclonal antibodies reverse phenotype internalization and tetramer formation -- Prevention of tumor development in a transgenic model identifies an adjuvant use for monoclonals -- How tumors worsen genetically.…”
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