Search Results - "proteins"
Suggested Topics within your search.
Suggested Topics within your search.
- metabolism 473
- Proteins 414
- genetics 327
- physiology 248
- Protein Conformation 186
- Signal Transduction 180
- chemistry 170
- Cellular signal transduction 152
- Protein Folding 142
- Metabolism 123
- Gene Expression Regulation 120
- drug therapy 119
- Molecular Chaperones 117
- immunology 113
- pathology 111
- Protein folding 101
- methods 98
- Neurodegenerative Diseases 97
- Genetic aspects 94
- Neoplasms 93
- Diseases 92
- Mitochondria 90
- Cancer 88
- pharmacology 84
- therapeutic use 83
- therapy 83
- Nervous system 82
- Transcription Factors 79
- Protein Biosynthesis 78
- Receptors 71
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961
Extracellular domain structures from calcium-sensing and GABA(B) receptors
Published 2019Subjects: Get full text
Series
Electronic Video -
962
Structure and activation of endothelin ETB receptor by endothelin
Published 2019Subjects: Get full text
Series
Electronic Video -
963
Roles of AMPK in energy homeostasis and nutrient sensing
Published 2021Subjects: Get full text
Series
Electronic Video -
964
Phospholipase C Gamma
Published 2007Table of Contents: “…Contents: PLC-gamma in growth factor signaling -- PLC-gamma as an enzyme -- Substrate and products -- PLC family members -- Domains -- Association of PLC-gamma with activated receptor tyrosine kinases and membranes -- Tyrosine phosphorylation sites of PLC-gamma -- PLC-gamma1 verses PLC-gamma2 -- Measurement of protein and enzymatic activation -- Downstream signaling by PLC-gamma in T cells -- PLC-gamma mediation of integrins during adhesion and spreading -- PLC-gamma biologic roles.…”
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Series
Electronic Video -
965
Global analysis of gene translation
Published 2009Table of Contents: “…Contents: Radiation-induced gene expression has long been considered to play a role in determining cellular radioresponse -- Analyses of single genes and whole genomes indicate that radiation-induced changes at the mRNA level do not correlate with changes in corresponding proteins -- Microarray analysis of polysome-bound RNA indicates that radiation modifies the translational activity of mRNA subpopulations, which correlates with protein products -- Gene translation is considerably more susceptible to radiation-induced changes than is the transcriptome -- Defining the genes whose translation is modified by radiation may provide an approach for identifying critical proteins and pathways that serve as determinants of radiosensitivity.…”
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Series
Electronic Video -
966
Phospholipase C Gamma
Published 2007Table of Contents: “…Contents: PLC-gamma in growth factor signaling -- PLC-gamma as an enzyme -- Substrate and products -- PLC family members -- Domains -- Association of PLC-gamma with activated receptor tyrosine kinases and membranes -- Tyrosine phosphorylation sites of PLC-gamma -- PLC-gamma1 verses PLC-gamma2 -- Measurement of protein and enzymatic activation -- Downstream signaling by PLC-gamma in T cells -- PLC-gamma mediation of integrins during adhesion and spreading -- PLC-gamma biologic roles.…”
Get full text
Series
Electronic Video -
967
Global analysis of gene translation
Published 2009Table of Contents: “…Contents: Radiation-induced gene expression has long been considered to play a role in determining cellular radioresponse -- Analyses of single genes and whole genomes indicate that radiation-induced changes at the mRNA level do not correlate with changes in corresponding proteins -- Microarray analysis of polysome-bound RNA indicates that radiation modifies the translational activity of mRNA subpopulations, which correlates with protein products -- Gene translation is considerably more susceptible to radiation-induced changes than is the transcriptome -- Defining the genes whose translation is modified by radiation may provide an approach for identifying critical proteins and pathways that serve as determinants of radiosensitivity.…”
Get full text
Series
Electronic Video -
968
Expression vs. function of ABC transporters at the blood-brain barrier
Published 2019Table of Contents: “…Contents: Introduction to the ABC superfamily and the blood-brain barrier (BBB) -- ABCB and P-glycoprotein (ABCB1) at the BBB -- ABCG and BCRP (ABCG2) at the BBB -- ABCC and the Multi-Drug Resistance Proteins (MRPs) at the BBB -- ABC in isolated human brain microvessels -- Pre-clinical and clinical impact in central nervous system research and drug development.…”
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Series
Electronic Video -
969
Expression vs. function of ABC transporters at the blood-brain barrier
Published 2019Table of Contents: “…Contents: Introduction to the ABC superfamily and the blood-brain barrier (BBB) -- ABCB and P-glycoprotein (ABCB1) at the BBB -- ABCG and BCRP (ABCG2) at the BBB -- ABCC and the Multi-Drug Resistance Proteins (MRPs) at the BBB -- ABC in isolated human brain microvessels -- Pre-clinical and clinical impact in central nervous system research and drug development.…”
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Series
Electronic Video -
970
The neuronal ceroid lipofuscinoses
Published 2016Table of Contents: “…Contents: Clinical features of the neuronal ceroid lipofuscinoses -- Genetics -- Genotype/phenotype correlations -- Protein epidemiology -- Mechanisms of neurodegeneration -- Treatment approaches.…”
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Series
Electronic Video -
971
Surface-mediated targeting of lentiviral vectors
Published 2014Table of Contents: “…Contents: In vivo and ex vivo gene therapy -- Cell entry modes of retroviral vectors -- Molecular functions of viral envelope proteins -- Introduction to surface targeting -- Targeting subtypes of lymphocytes and hematopoietic stem cells (Ex vivo) -- In vivo targeting (local vs. systemic administration).…”
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Series
Electronic Video -
972
The proteomic revolution
Published 2022Table of Contents: “…Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine.…”
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Series
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973
Colorectal cancer and the rare variant hypothesis
Published 2020Subjects: Get full text
Series
Electronic Video -
974
Colorectal cancer and the rare variant hypothesis
Published 2020Subjects: Get full text
Series
Electronic Video -
975
The proteomic revolution
Published 2022Table of Contents: “…Contents: The proteomic revolution -- Proteomics is the best measure of phenotype (biomarkers) -- Slow Off-rate Modified Aptamers (SOMAmers) are breakthrough protein binding reagents -- SOMAmers are multiplexed to perform SOMAscan assay, which measures >1000 proteins in small sample volumes using DNA measurement tools to identify and quantify proteins bound by SOMAmers -- Applications of SOMAscan to date include finding valid protein biomarkers for lung cancer, cardiovascular risk, pre-term birth, pancreatic cancer, mesothelioma, and many other diseases and conditions -- Ability to do comprehensive longitudinal proteomics studies will revolutionize medicine.…”
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Series
Electronic Video -
976
The neutral and nearly neutral theories of molecular evolution part 2 of 2 /
Published 2022Table of Contents: “…Contents: Nearly neutral model -- Distribution of fitness effects of new mutations -- Predictions of Neutral Theory -- Evolutionary implications of nearly neutral evolution -- Protein stability as an example of evolutionary dynamics.…”
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Series
Electronic Video -
977
The neutral and nearly neutral theories of molecular evolution part 2 of 2 /
Published 2022Table of Contents: “…Contents: Nearly neutral model -- Distribution of fitness effects of new mutations -- Predictions of Neutral Theory -- Evolutionary implications of nearly neutral evolution -- Protein stability as an example of evolutionary dynamics.…”
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Series
Electronic Video -
978
Visualization of transcription factor interactions in living cells
Published 2014Table of Contents: “…Contents: Transcription regulatory proteins -- Combinatorial control of gene expression -- Visualization of transcription factor interactions and modifications in living cells -- New methods development -- Bimolecular fluorescence complementation (BiFC) assays -- Ubiquitin mediated fluorescence complementation (UbFC) assays.…”
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Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
979
Visualization of transcription factor interactions in living cells
Published 2014Table of Contents: “…Contents: Transcription regulatory proteins -- Combinatorial control of gene expression -- Visualization of transcription factor interactions and modifications in living cells -- New methods development -- Bimolecular fluorescence complementation (BiFC) assays -- Ubiquitin mediated fluorescence complementation (UbFC) assays.…”
Get full text
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)
Electronic Video -
980
Structure of thrombin, a Janus-headed proteinase
Published 2007Subjects: Get full text
Series
Electronic Video