Search Results - "proteins"

Discovery of schizophrenia drug targets from DISC1 mechanisms

Table of Contents: “…Contents: Discovery of DISC1 -- Potential Therapeutics strategies based on the structure and motif of DISC1 protein -- DISC1-associated pathways as drug targets -- Molecular complexities of DISC1.…”
Get full text
Series (Drug discovery and development in the neurosciences)
Series (Small molecule drug discovery).

Nuclear organization and gene expression

Table of Contents: “…Contents: Current understanding of the organization of the mammalian cell nucleus and how this organization impacts on gene expression -- in-vivo studies of gene expression as a result of the concerted processes of transcription, mRNA processing, messenger ribonucleoprotein particle (mRNP) export and translation -- studies of spatial and temporal aspects of critical cellular processes within the context of the living cell -- development of a cell system that allows the visualization of a transcription site and its mRNA and protein products directly in living cells -- evaluation of spatial and temporal changes in chromatin structure, mRNA synthesis and factor association/disassociation during the transition from a transcriptionally inactive to an active state -- understanding of the in-vivo dynamics of gene expression will provide the basis from which to elucidate spatial and/or temporal alterations that occur in cells associated with various disease states.…”
Get full text
Series (Epigenetics)
Series (From DNA to proteins)

Nuclear organization and gene expression

Table of Contents: “…Contents: Current understanding of the organization of the mammalian cell nucleus and how this organization impacts on gene expression -- in-vivo studies of gene expression as a result of the concerted processes of transcription, mRNA processing, messenger ribonucleoprotein particle (mRNP) export and translation -- studies of spatial and temporal aspects of critical cellular processes within the context of the living cell -- development of a cell system that allows the visualization of a transcription site and its mRNA and protein products directly in living cells -- evaluation of spatial and temporal changes in chromatin structure, mRNA synthesis and factor association/disassociation during the transition from a transcriptionally inactive to an active state -- understanding of the in-vivo dynamics of gene expression will provide the basis from which to elucidate spatial and/or temporal alterations that occur in cells associated with various disease states.…”
Get full text
Series (Epigenetics)
Series (From DNA to proteins)

EGF receptor family targets for cancer therapeutics /

Subjects: Get full text
Series

EGF-TM7 receptors

Subjects: Get full text
Series

Activation of PTK receptors in solid human tumors

Subjects: Get full text
Series

Fibrinolysis

Subjects: Get full text
Series

EGFR targeted therapies in lung cancer

Subjects: Get full text
Series

Molecular biology of Alzheimer's disease genes and mechanisms involved in amyloid generation /

Subjects: An electronic book accessible through the World Wide Web; click to view

Activation of PTK receptors in solid human tumors

Subjects: Get full text
Series

Fibrinolysis

Subjects: Get full text
Series

EGFR targeted therapies in lung cancer

Subjects: Get full text
Series

EGF-TM7 receptors

Subjects: Get full text
Series

Imatinib as a paradigm of targeted cancer therapies

Subjects: Get full text
Series (Signal transduction via protein tyrosine kinase receptors)
Series (Small molecule drug discovery)

Self-splicing intron RNAs ribozymes, parasites and agents of genomic change /

Subjects: Get full text
Series

Integrated view on a eukaryotic osmoregulation system

Table of Contents: “…Contents: Osmoregulation -- Cell compression and macromolecular crowding -- Osmolyte accumulation -- Metabolism and signalling -- Modelling, simulation and prediction -- Multi-level control of osmolyte accumulation -- Mitogen activated protein kinase signalling -- Signalling crosstalk -- Synthetic biology approaches to osmoregulation.…”
Get full text
Series

Self-splicing intron RNAs ribozymes, parasites and agents of genomic change /

Subjects: Get full text
Series

Integrated view on a eukaryotic osmoregulation system

Table of Contents: “…Contents: Osmoregulation -- Cell compression and macromolecular crowding -- Osmolyte accumulation -- Metabolism and signalling -- Modelling, simulation and prediction -- Multi-level control of osmolyte accumulation -- Mitogen activated protein kinase signalling -- Signalling crosstalk -- Synthetic biology approaches to osmoregulation.…”
Get full text
Series

Complement as a therapeutic target

Subjects: Get full text
Series (Complement system)
Series (Macular degeneration)

Subversion of complement by bacteria

Subjects: Get full text
Series