Search Results - "proteins"

Traffic problems inherited disease and intracellular trafficking defect /

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Traffic problems inherited disease and intracellular trafficking defect /

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The role of MAPT (Tau) in neurodegenerative disease one bullet with many triggers /

Table of Contents: “…Contents: Medical importance of tauopathies -- Microtubule Associated Protein Tau (MAPT) is incorporated into neurofibrillary lesions -- Mutations in the MAPT gene give rise to Frontotemporal dementia with parkinsonism (FTDP-17) -- Common variability in the MAPT, the so-called H1/H1 haplotype and sporadic tauopathies -- Progressive supranuclear Palsy and Cortico-basal degeneration -- Constitutive and conditional transgenic mouse models of tauopathy -- The JNPL3 mouse model of tauopathy -- Neurofibrillary tau pathology in the JNPL3 mice -- A-beta and MAPT pathologies can interact during the development of Alzheimer's disease -- Conditional rTg4510 model of tauopathy -- Major mechanism of neurodegeneration in tauopathy -- Potential therapeutic applications.…”
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The role of MAPT (Tau) in neurodegenerative disease one bullet with many triggers /

Table of Contents: “…Contents: Medical importance of tauopathies -- Microtubule Associated Protein Tau (MAPT) is incorporated into neurofibrillary lesions -- Mutations in the MAPT gene give rise to Frontotemporal dementia with parkinsonism (FTDP-17) -- Common variability in the MAPT, the so-called H1/H1 haplotype and sporadic tauopathies -- Progressive supranuclear Palsy and Cortico-basal degeneration -- Constitutive and conditional transgenic mouse models of tauopathy -- The JNPL3 mouse model of tauopathy -- Neurofibrillary tau pathology in the JNPL3 mice -- A-beta and MAPT pathologies can interact during the development of Alzheimer's disease -- Conditional rTg4510 model of tauopathy -- Major mechanism of neurodegeneration in tauopathy -- Potential therapeutic applications.…”
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Proteomics of biological systems protein phosphorylation using mass spectrometry techniques / by Ham, Bryan M.

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GPCRs and pain

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Considerations for ensuring safety and efficacy of vaccines and therapeutic proteins manufactured by using platform approaches summary of a workshop /

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Conserved allosteric sodium in class A GPCRs part 2 of 2, Na+ dynamics in GPCR signaling /

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MAPK signalling regulation and cancer lessons from fission yeast /

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MAPK signalling regulation and cancer lessons from fission yeast /

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Conserved allosteric sodium in class A GPCRs part 2 of 2, Na+ dynamics in GPCR signaling /

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The Eph receptor family

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Structural basis of LSD signaling

Table of Contents: “…Contents: Lysergic Acid Diethylamide (LSD) history, physiological effects, and utility -- G Protein-coupled serotonin receptor signalling -- Structure of LSD-bound serotonin receptor -- Uniquely slow LSD binding kinetics -- Binding kinetics are linked to LSD’s pharmacological properties.…”
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Adhesion GPCRs in nervous system development and disease

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Cellular pathways linked to dominant Parkinson's disease

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Mechanistic aspects of chaperonin GroEL/ES function

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Mechanistic aspects of chaperonin GroEL/ES function

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Conserved allosteric sodium in class A GPCRs part 1 of 2, GPCR structure and allosteric effects /

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Conserved allosteric sodium in class A GPCRs part 1 of 2, GPCR structure and allosteric effects /

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Discovery of schizophrenia drug targets from DISC1 mechanisms

Table of Contents: “…Contents: Discovery of DISC1 -- Potential Therapeutics strategies based on the structure and motif of DISC1 protein -- DISC1-associated pathways as drug targets -- Molecular complexities of DISC1.…”
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Series (Drug discovery and development in the neurosciences)
Series (Small molecule drug discovery).