Search Results - "proteins"

  1. 841
  2. 842

    Quantitative analysis of receptor allosterism and its implication for drug discovery

    Published 2015
    Table of Contents: “…Contents: G protein-coupled receptors (GPCRs) -- Receptor agonism and allosterism -- Orthosteric and allosteric binders -- Inverse, partial and full agonists -- Positive, silent and negative allosteric modulators (PAMs, SAMs and NAMs) -- Allosteric two-state model and general operational model with constitutive receptor activity -- Optimal design of experiment -- Global curve fitting analysis of affinity and efficacy parameters -- Beta supremacy -- Monte Carlo simulations.…”
    Get full text
    Series
    Electronic Video
  3. 843

    Chaperone systems of the endoplasmic reticulum

    Published 2012
    Table of Contents: “…Contents: Communication between cells -- Angiogenesis -- Secretion of effector molecules -- Cell migration/homing -- Proteins synthesis & folding -- Molecular chaperone families in the ER -- Antibody formation -- BiP: a soluble Hsp70 protein -- ATPase and DnaK peptide binding domains -- CH1 domain -- The formation of disulfide bonds -- ATPase cycle of BiP -- Disruption of BiP/GRP78 gene in mice -- Highly virulent subtilase toxin -- BiP functions in ER -- ER DnaJ proteins -- Gal-4-BiP ATPase domain fusion protein -- BAP/Sil1: a nucleotide releasing factor -- Potential consequences of BAP/Sil1 loss and mutations -- The family of large Hsp70 proteins -- The two functions of GRP170 -- GRP94 as an essential gene- Immunophilins -- lymphoid specific chaperone: pERp1.…”
    Get full text
    Series
    Electronic Video
  4. 844

    Translation initiation

    Published 2007
    Subjects:
    Get full text
    Series
    Electronic Video
  5. 845

    The VEGF family by Alitalo, Kari

    Published 2007
    Subjects:
    Get full text
    Series
    Electronic Video
  6. 846

    Translation initiation

    Published 2007
    Subjects:
    Get full text
    Series
    Electronic Video
  7. 847

    The VEGF family by Alitalo, Kari

    Published 2007
    Subjects:
    Get full text
    Series
    Electronic Video
  8. 848

    Chaperone systems of the endoplasmic reticulum

    Published 2012
    Table of Contents: “…Contents: Communication between cells -- Angiogenesis -- Secretion of effector molecules -- Cell migration/homing -- Proteins synthesis & folding -- Molecular chaperone families in the ER -- Antibody formation -- BiP: a soluble Hsp70 protein -- ATPase and DnaK peptide binding domains -- CH1 domain -- The formation of disulfide bonds -- ATPase cycle of BiP -- Disruption of BiP/GRP78 gene in mice -- Highly virulent subtilase toxin -- BiP functions in ER -- ER DnaJ proteins -- Gal-4-BiP ATPase domain fusion protein -- BAP/Sil1: a nucleotide releasing factor -- Potential consequences of BAP/Sil1 loss and mutations -- The family of large Hsp70 proteins -- The two functions of GRP170 -- GRP94 as an essential gene- Immunophilins -- lymphoid specific chaperone: pERp1.…”
    Get full text
    Series
    Electronic Video
  9. 849

    Visualization of transcription factor interactions in living cells

    Published 2014
    Table of Contents: “…Contents: Transcription regulatory proteins -- Combinatorial control of gene expression -- Visualization of transcription factor interactions and modifications in living cells -- New methods development -- Bimolecular fluorescence complementation (BiFC) assays -- Ubiquitin mediated fluorescence complementation (UbFC) assays.…”
    Get full text
    Series (Eukaryotic gene regulation)
    Series (Epigenetics, chromatin, transcription and cancer)
    Electronic Video
  10. 850

    The phagocytic synapse in distinguishing particulate and soluble stimuli

    Published 2013
    Subjects:
    Get full text
    Series
    Electronic Video
  11. 851

    The phagocytic synapse in distinguishing particulate and soluble stimuli

    Published 2013
    Subjects:
    Get full text
    Series
    Electronic Video
  12. 852

    The interplay between protein phosphorylation and ubiquitylation in the NF-ĸB pathway

    Published 2010
    Table of Contents: “…Contents: Ubiquitination is a reversible covalent modification, akin to phosphorylation -- Ubiquitination regulates protein kinase activity through proteasome-independent mechanisms -- K63-linked polyubiquitination activates TAK1 and IKK in the NF-kappaB pathway -- Deubiquitination enzymes inhibit protein kinases in the NF-kappaB pathway -- Protein kinase regulation by ubiquitin is important in innate and adaptive immunity.…”
    Get full text
    Series
    Electronic Video
  13. 853

    Identification of a new coronavirus-specific RNA export protein complex

    Published 2020
    Table of Contents: “…Contents: Rationale for the search and investigation of coronavirus-specific replication machinery -- Identification of a new coronavirus-specific RNA export protein complex -- The stages of coronavirus entry into human cells and the role of the RNA export complex -- Innovative research approaches to the detection of the new protein complex -- Implications for the development of coronavirus-specific antiviral drugs -- Next steps in the characterization of the new protein complex as a drug target.…”
    Get full text
    Series
    Electronic Audio
  14. 854

    The interplay between protein phosphorylation and ubiquitylation in the NF-ĸB pathway

    Published 2010
    Table of Contents: “…Contents: Ubiquitination is a reversible covalent modification, akin to phosphorylation -- Ubiquitination regulates protein kinase activity through proteasome-independent mechanisms -- K63-linked polyubiquitination activates TAK1 and IKK in the NF-kappaB pathway -- Deubiquitination enzymes inhibit protein kinases in the NF-kappaB pathway -- Protein kinase regulation by ubiquitin is important in innate and adaptive immunity.…”
    Get full text
    Series
    Electronic Video
  15. 855

    The interplay between protein phosphorylation and ubiquitylation in the NF-ĸB pathway

    Published 2010
    Table of Contents: “…Contents: Ubiquitination is a reversible covalent modification, akin to phosphorylation -- Ubiquitination regulates protein kinase activity through proteasome-independent mechanisms -- K63-linked polyubiquitination activates TAK1 and IKK in the NF-kappaB pathway -- Deubiquitination enzymes inhibit protein kinases in the NF-kappaB pathway -- Protein kinase regulation by ubiquitin is important in innate and adaptive immunity.…”
    Get full text
    Series
    Electronic Video
  16. 856

    Identification of a new coronavirus-specific RNA export protein complex

    Published 2020
    Table of Contents: “…Contents: Rationale for the search and investigation of coronavirus-specific replication machinery -- Identification of a new coronavirus-specific RNA export protein complex -- The stages of coronavirus entry into human cells and the role of the RNA export complex -- Innovative research approaches to the detection of the new protein complex -- Implications for the development of coronavirus-specific antiviral drugs -- Next steps in the characterization of the new protein complex as a drug target.…”
    Get full text
    Series
    Electronic Audio
  17. 857

    Activation of gene expression by double-stranded RNAs

    Published 2017
    Subjects:
    Get full text
    Series
    Electronic Video
  18. 858

    Activation of gene expression by double-stranded RNAs

    Published 2017
    Subjects:
    Get full text
    Series
    Electronic Video
  19. 859
  20. 860

    TRAIL-induced apoptosis from analysis of the death-inducing signalling complex (DISC) to clinical applicability /

    Published 2007
    Subjects: “…Death Domain Receptor Signaling Adaptor Proteins. 110861…”
    Get full text
    Series
    Electronic Video