Search Results - "proteins"

Information content in sequences and its relation to protein structure prediction

Table of Contents: “…Contents: Concept of information -- Variation in protein sequences -- Patterns -- Comparison with language -- Measuring information -- Genetic code -- Correlated substitutions -- Proteins' high tolerance for substitutions -- Protein structure prediction -- Dependence of structure on environment.…”
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Generation and propagation of infectious prions by cyclic amplification of protein misfolding

Table of Contents: “…Contents: Prions as infectious proteins and the mechanism of replication -- The rationale and proof of concept for the PMCA technology -- Multiple applications of PMCA -- Generation of infectious prions by PMCA -- Studies of prion strains and species barrier -- Use of PMCA for prion detection and diagnosis.…”
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The regulation of MAP kinase signalling by dual-specificity protein phosphatases

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BMC Structural Biology

Subjects: Open Access

BMC Structural Biology

Subjects: Open Access

Structure and function of adhesion GPCRs and their ligands

Table of Contents: “…Contents: The history, biological functions and architecture of adhesion GPCRs -- The conserved GAIN domain -- Working models for adhesion GPCR activation -- The structures of adhesion GPCR extracellular regions and their ligands -- Similarity of adhesion GPCRs to hormone receptors -- Drugs might affect adhesion GPCRs via the extracellular regions or protein-protein interaction sites.…”
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Cytochrome b5 reductase deficiency and hereditary methemoglobinemia

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Cytochrome b5 reductase deficiency and hereditary methemoglobinemia

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Traffic problems inherited disease and intracellular trafficking defect /

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Chaperonin-containing TCP-1 (CCT), actin springs, and protein folding fluxes

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Chaperonin-containing TCP-1 (CCT), actin springs, and protein folding fluxes

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Subversion of the complement system by viruses

Table of Contents: “…Contents: Recognition of viruses by the complement system -- Role of complement in antiviral immunity -- Complement subversion by viruses: molecular mimicry, molecular piracy, use of complement receptors and regulators for cellular entry, and modulation of complement protein expression.…”
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Subversion of the complement system by viruses

Table of Contents: “…Contents: Recognition of viruses by the complement system -- Role of complement in antiviral immunity -- Complement subversion by viruses: molecular mimicry, molecular piracy, use of complement receptors and regulators for cellular entry, and modulation of complement protein expression.…”
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Mechanisms regulating STIM expression and function in Ca2+ signaling

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Mechanisms regulating STIM expression and function in Ca2+ signaling

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CML genetic paradigm of targeted therapy, part 2 of 2 /

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Super-resolution imaging of GPCR oligomers applications and functional roles /

Table of Contents: “…Contents: Introduction to G Protein-Coupled Receptors (GPCRs) -- Gonadotrophin hormone receptor (GpHR) function -- Role of GPCR oligomerization in vivo through studies of GpHRs -- Single molecule/Super-resolution imaging -- Super-resolution of imaging of GPCRs and GpHRs via PALM -- Applications of PALM to structure/function analysis of GPCR oligomers.…”
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Super-resolution imaging of GPCR oligomers applications and functional roles /

Table of Contents: “…Contents: Introduction to G Protein-Coupled Receptors (GPCRs) -- Gonadotrophin hormone receptor (GpHR) function -- Role of GPCR oligomerization in vivo through studies of GpHRs -- Single molecule/Super-resolution imaging -- Super-resolution of imaging of GPCRs and GpHRs via PALM -- Applications of PALM to structure/function analysis of GPCR oligomers.…”
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Self-splicing intron RNAs ribozymes, parasites and agents of genomic change /

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PI3K/AKT signaling In cancer

Table of Contents: “…Contents: PI3K/AKT signal transduction pathway -- Tumors with frequent dysregulation of PI3K signalling -- Modalities for inhibiting PI3K-AKT signaling currently in development -- AKT1/2 inhibitor (Merck) -- PI3K/AKT in breast cancer -- AKTi-1/2 inhibits AKT signaling and causes G1 arrest -- The Herceptin-resistant -- Effect of AKT inhibition on glucose levels -- Mutated elements in mitogenic signaling pathways in tumors -- Coexistent K-Ras or B-Raf mutation -- Genes encoding several components of mitogenic signaling pathways are mutationally activated in tumors -- Integrators of multiple signaling pathways (OR-gates) -- The effects of combined inhibition of AKT and MAPK on the phosphorylation of translational regulatory proteins -- Knockdown of 4EBP1 expression -- Feedback inhibition of insulin/IGF-1 signaling -- The concept of feedback -- Clinical effects of Rapamycin-like drugs -- mTORC1 vs. …”
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