Search Results - "proteins"

Negative regulation of RTKs receptor ubiquitylation, endocytosis and feedback loops /

Table of Contents: “…Contents: Signal transduction by growth factor-activated protein tyrosine kinase receptors -- Receptor endocytosis -- The three vesicular sorting steps occurring at the plasma membrane, in endosomes and in a pre-lysosomal compartment -- The emerging role of mono-ubiquitin and ubiquitin-binding proteins in sorting of active receptors to degradation.…”
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The molecular basis of insulin action

Table of Contents: “…Contents: Mechanisms to diabetes -- The insulin response -- Growth factor receptor tyrosine kinases -- The insulin receptor -- The substrate hypothesis of insulin action -- The family of Irs-proteins -- The insulin signaling cascade -- Role of the Irs2 signaling system.…”
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RTKs activate the ERK 1/2 MAPK cascade

Subjects: “…Receptor Protein-Tyrosine Kinases. 110340…”
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SH2-containing PTPs (Shps) in RTK signaling and disease

Subjects: “…Receptor Protein-Tyrosine Kinases. 110364…”
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Structural basis for Fibroblast Growth Factor (FGF) receptor activation implications in development and disease /

Subjects: “…Receptor Protein-Tyrosine Kinases. 110513…”
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Negative regulation of RTKs receptor ubiquitylation, endocytosis and feedback loops /

Table of Contents: “…Contents: Signal transduction by growth factor-activated protein tyrosine kinase receptors -- Receptor endocytosis -- The three vesicular sorting steps occurring at the plasma membrane, in endosomes and in a pre-lysosomal compartment -- The emerging role of mono-ubiquitin and ubiquitin-binding proteins in sorting of active receptors to degradation.…”
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The molecular basis of insulin action

Table of Contents: “…Contents: Mechanisms to diabetes -- The insulin response -- Growth factor receptor tyrosine kinases -- The insulin receptor -- The substrate hypothesis of insulin action -- The family of Irs-proteins -- The insulin signaling cascade -- Role of the Irs2 signaling system.…”
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RTKs activate the ERK 1/2 MAPK cascade

Subjects: “…Receptor Protein-Tyrosine Kinases. 110340…”
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SH2-containing PTPs (Shps) in RTK signaling and disease

Subjects: “…Receptor Protein-Tyrosine Kinases. 110364…”
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Structural basis for Fibroblast Growth Factor (FGF) receptor activation implications in development and disease /

Subjects: “…Receptor Protein-Tyrosine Kinases. 110513…”
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From CagA to CagA the metamorphoses of the Helicobacter pylori's cytotoxin-associated gene A into the cancer-associated gene A /

Subjects: “…cagA protein, Helicobacter pylori. 109205…”
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Adapting proteostasis to ameliorate aggregation-associated amyloid diseases

Table of Contents: “…Contents: Protein folding, misfolding, aggregation -- The proteostasis network and its regulation -- Gain and loss of function diseases -- The transthyretin (TTR) amyloidosis -- Kinetic stabilizers & clinical trial results -- Tafamidis & Diflunisal: evidence for the amyloid hypothesis -- Improving protein misfolding/aggregation diseases -- The unfolded protein response (UPR) and its arm-selective activators -- ATF6 activation & reduction of TTR mutant -- Clinical trials in amyloidosis with cardiac involvement.…”
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Adapting proteostasis to ameliorate aggregation-associated amyloid diseases

Table of Contents: “…Contents: Protein folding, misfolding, aggregation -- The proteostasis network and its regulation -- Gain and loss of function diseases -- The transthyretin (TTR) amyloidosis -- Kinetic stabilizers & clinical trial results -- Tafamidis & Diflunisal: evidence for the amyloid hypothesis -- Improving protein misfolding/aggregation diseases -- The unfolded protein response (UPR) and its arm-selective activators -- ATF6 activation & reduction of TTR mutant -- Clinical trials in amyloidosis with cardiac involvement.…”
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Polycomb epigenetic mechanisms Part 2 of 2, methylation of DNA /

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The regulation of MAP kinase signalling by dual-specificity protein phosphatases

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Information content in sequences and its relation to protein structure prediction

Table of Contents: “…Contents: Concept of information -- Variation in protein sequences -- Patterns -- Comparison with language -- Measuring information -- Genetic code -- Correlated substitutions -- Proteins' high tolerance for substitutions -- Protein structure prediction -- Dependence of structure on environment.…”
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Generation and propagation of infectious prions by cyclic amplification of protein misfolding

Table of Contents: “…Contents: Prions as infectious proteins and the mechanism of replication -- The rationale and proof of concept for the PMCA technology -- Multiple applications of PMCA -- Generation of infectious prions by PMCA -- Studies of prion strains and species barrier -- Use of PMCA for prion detection and diagnosis.…”
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The regulation of MAP kinase signalling by dual-specificity protein phosphatases

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Information content in sequences and its relation to protein structure prediction

Table of Contents: “…Contents: Concept of information -- Variation in protein sequences -- Patterns -- Comparison with language -- Measuring information -- Genetic code -- Correlated substitutions -- Proteins' high tolerance for substitutions -- Protein structure prediction -- Dependence of structure on environment.…”
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Generation and propagation of infectious prions by cyclic amplification of protein misfolding

Table of Contents: “…Contents: Prions as infectious proteins and the mechanism of replication -- The rationale and proof of concept for the PMCA technology -- Multiple applications of PMCA -- Generation of infectious prions by PMCA -- Studies of prion strains and species barrier -- Use of PMCA for prion detection and diagnosis.…”
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