Search Results - "proteins"
Suggested Topics within your search.
Suggested Topics within your search.
- metabolism 473
- Proteins 414
- genetics 327
- physiology 248
- Protein Conformation 186
- Signal Transduction 180
- chemistry 170
- Cellular signal transduction 152
- Protein Folding 142
- Metabolism 123
- Gene Expression Regulation 120
- drug therapy 119
- Molecular Chaperones 117
- immunology 113
- pathology 111
- Protein folding 101
- methods 98
- Neurodegenerative Diseases 97
- Genetic aspects 94
- Neoplasms 93
- Diseases 92
- Mitochondria 90
- Cancer 88
- pharmacology 84
- therapeutic use 83
- therapy 83
- Nervous system 82
- Transcription Factors 79
- Protein Biosynthesis 78
- Receptors 71
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621
Factor VIII and Haemophilia A
Published 2016Table of Contents: “…-- Different types of factor VIII gene mutations -- Loss of protein or loss of function -- Structural interpretation of protein dysfunction -- Other rare causes of FVIII deficiency.…”
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622
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623
Two is the key to 14-3-3 dimeric mechanical & signalling devices /
Published 2010Subjects: “…14-3-3 Proteins chemistry. 108916…”
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624
The HGF receptor a targettable regulator of invasive growth /
Published 2007Subjects: “…Proto-Oncogene Proteins c-met. 110684…”
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625
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626
How aminoacyl-tRNA synthetases translate the genetic code
Published 2008Table of Contents: “…Contents: Fidelity of protein synthesis -- Architecture of aminoacyl-tRNA synthetase -- ATP and amino acid recognition by the two classes of synthetases -- The activation reaction -- Cognate tRNA recognition by synthetases -- The aminoacylation reaction -- Direct and indirect routes to aminoacylation -- Error correction (editing) by aminoacyl-tRNA synthetases -- Aminoacyl-tRNA synthetases as antibiotic targets.…”
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627
The HGF receptor a targettable regulator of invasive growth /
Published 2007Subjects: “…Proto-Oncogene Proteins c-met. 110684…”
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628
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629
How aminoacyl-tRNA synthetases translate the genetic code
Published 2008Table of Contents: “…Contents: Fidelity of protein synthesis -- Architecture of aminoacyl-tRNA synthetase -- ATP and amino acid recognition by the two classes of synthetases -- The activation reaction -- Cognate tRNA recognition by synthetases -- The aminoacylation reaction -- Direct and indirect routes to aminoacylation -- Error correction (editing) by aminoacyl-tRNA synthetases -- Aminoacyl-tRNA synthetases as antibiotic targets.…”
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630
Two is the key to 14-3-3 dimeric mechanical & signalling devices /
Published 2010Subjects: “…14-3-3 Proteins chemistry. 108916…”
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Series
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631
Overview of eukaryotic molecular chaperones in the cytosol
Published 2020Table of Contents: “…Contents: Protein folding and molecular chaperones -- Hsp70/Hsc70 -- Co-chaperones of Hsc70 -- Chaperonin TRiC/CCT -- Prefoldin -- Hsp90 -- Co-chaperones of Hsp90 -- Specialized co-chaperones -- Heat shock protein chaperones.…”
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632
Overview of eukaryotic molecular chaperones in the cytosol
Published 2020Table of Contents: “…Contents: Protein folding and molecular chaperones -- Hsp70/Hsc70 -- Co-chaperones of Hsc70 -- Chaperonin TRiC/CCT -- Prefoldin -- Hsp90 -- Co-chaperones of Hsp90 -- Specialized co-chaperones -- Heat shock protein chaperones.…”
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633
Subversion of the complement system by viruses
Published 2018Table of Contents: “…Contents: Recognition of viruses by the complement system -- Role of complement in antiviral immunity -- Complement subversion by viruses: molecular mimicry, molecular piracy, use of complement receptors and regulators for cellular entry, and modulation of complement protein expression.…”
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634
RAS pathway and disease neurofibromatosis and beyond /
Published 2014Table of Contents: “…Contents: Neurofibromatosis type 1 (NF1) -- NIH diagnostic criteria (Seven criteria for NF1) -- NF1 and the RAS pathway -- NF1 tumour biology -- Neurofibromin deficiency -- Two types of neurofibromas -- Plexiform neurofibroma in the neck and mouth -- Mechanisms of disease -- Mouse models of neurofibroma formation -- Imatinib mesylate treatment -- Clinical aspects of glomus tumours of fingertips -- Gastrointestinal stromal tumours -- MPNST in NF1 -- FDG-PET as a diagnostic tool -- Hotspots for recombination & NF1 microdeletion -- SUZ12-loss -- Cafe-au-lait (CAL) macules -- Skeletal defects in NF1 -- Learning disabilities in NF1 -- Simvastatin treatment for cognitive deficits -- Mosaicism for NF1 mutation -- Diagnostic problems -- SPRED1 mutations & molecular mechanism of Legius syndrome -- The RAS pathway proteins & genetic syndromes (RASopathies).…”
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635
RAS pathway and disease neurofibromatosis and beyond /
Published 2014Table of Contents: “…Contents: Neurofibromatosis type 1 (NF1) -- NIH diagnostic criteria (Seven criteria for NF1) -- NF1 and the RAS pathway -- NF1 tumour biology -- Neurofibromin deficiency -- Two types of neurofibromas -- Plexiform neurofibroma in the neck and mouth -- Mechanisms of disease -- Mouse models of neurofibroma formation -- Imatinib mesylate treatment -- Clinical aspects of glomus tumours of fingertips -- Gastrointestinal stromal tumours -- MPNST in NF1 -- FDG-PET as a diagnostic tool -- Hotspots for recombination & NF1 microdeletion -- SUZ12-loss -- Cafe-au-lait (CAL) macules -- Skeletal defects in NF1 -- Learning disabilities in NF1 -- Simvastatin treatment for cognitive deficits -- Mosaicism for NF1 mutation -- Diagnostic problems -- SPRED1 mutations & molecular mechanism of Legius syndrome -- The RAS pathway proteins & genetic syndromes (RASopathies).…”
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636
Bioencapsulation in silica-based nanoporous sol-gel glasses
Published 2010Subjects: An electronic book accessible through the World Wide Web; click to view
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637
Function and regulation of the PDK1 kinase
Published 2010Table of Contents: “…Contents: The insulin cascade -- Approaches to study the insulin signalling pathway -- GSK3 regulation of glycogen synthase by insulin -- Inactivation of GSK3 by PI3K -- GSK3 inactivation by other kinases -- Protein Kinase B (Akt) -- PKB signal transduction -- Substrate specificity of PKB -- Activation of PKB by insulin -- Phosphorylation of PKB on Thr308 and Ser473 -- PKB phosphorylation on the catalytic domain -- How insulin locates PKB to the plasma membrane -- PKB translocation to the cell membrane -- Molecular mechanism of PKB activation -- Phosphorylation of PKB -- Discovery of PDK1 -- Primary structure of human PDK1 -- PIP3 requirement for PDK1 activation of PKB -- PDK1/2 phosphorylation of PKB -- The inability of PIP3 to activate PDK1 in vitro -- PKB in muscle-specific PDK1 knockout mice -- Glycogen synthase inactivation by GSK3 -- GSK3 & glycogen synthase in muscle-specific PDK1 knockout mice -- GSK3 knock-in mice -- Analysis of GSK3 isoforms in knock-in mice -- Glycogen synthase activity in knock-in mice -- Insulin effects mediated by protein kinases -- S6K, SGK and PKC activation -- PDK1 as a "master upstream kinase" -- S6K in muscle-specific PDK1 knockout mice -- PDK1 activation of 24 AGC kinase members -- Regulation of the PDK1 pathway -- The PDK1 kinase domain -- Defining the PIF-pocket by knock-in mutation -- S6K in PDK1 PIF-pocket knock-in mutation -- The role of PIP3 binding to the PH domain -- Inhibition of PKB in PDK1 PH domain knock-in cells -- The role of the PDK1 in cancer -- Evaluation of PDK1 as a drug target -- Generation of PDK1 hypomorphic mice -- PTEN and its effect in cancer -- PDK1 and PTEN in tumours.…”
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638
Genomic insights into gene regulation by cohesin
Published 2014Subjects: “…Chromosomal proteins. 104481…”
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639
Genomic insights into gene regulation by cohesin
Published 2014Subjects: “…Chromosomal proteins. 104481…”
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640
Adapting proteostasis to ameliorate aggregation-associated amyloid diseases
Published 2018Table of Contents: “…Contents: Protein folding, misfolding, aggregation -- The proteostasis network and its regulation -- Gain and loss of function diseases -- The transthyretin (TTR) amyloidosis -- Kinetic stabilizers & clinical trial results -- Tafamidis & Diflunisal: evidence for the amyloid hypothesis -- Improving protein misfolding/aggregation diseases -- The unfolded protein response (UPR) and its arm-selective activators -- ATF6 activation & reduction of TTR mutant -- Clinical trials in amyloidosis with cardiac involvement.…”
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