Search Results - "proteins"

Prediction and design of protein structures and interactions

Table of Contents: “…Contents: Modeling of macromolecular interactions -- Conformational sampling -- Docking low-resolution search -- High resolution refinement -- Docking protocol -- Side chain flexibility and modeling -- Ab initio structure prediction -- Computational protein design -- Simultaneous sequence-structure optimization -- Protein interface design -- Properties of free energy landscapes of macromolecules.…”
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Biogenesis of cellular iron-sulfur proteins part II, the essential role of mitochondria and the CIA machinery /

Table of Contents: “…Contents: Cytosolic and nuclear Fe/S proteins maturation -- Role of mitochondria in cytosolic and nuclear Fe/S protein biogenesis -- Functions of proteins involved in Fe/S protein biogenesis -- Importance of Fe/S protein biogenesis for genome maintenance.…”
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Three decades of protein phosphorylation and cancer the identification and characterization of the src gene product /

Table of Contents: “…Contents: The avian sarcoma virus genome and its products -- Cellular responses to the viral oncoprotein, Src -- The search for the ASV src gene product -- The RNA genome of avian sarcoma virus -- Searching for Src a function -- Impact of Src protein identification and characterization.…”
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Phosphorylase and the origin of reversible protein phosphorylation

Table of Contents: “…Contents: A historical account of the discovery of reversible protein phosphorylation -- Video clips of the late Edwin Krebs speaking about our early work -- Reversible protein phosphorylation represents one of the most prevalent mechanism by which cellular events are regulated -- Establishment of the first hormonal cascade of successive enzymatic reactions initiated by cAMP.…”
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Protein kinase structure, function and regulation

Table of Contents: “…Contents: Overview of protein kinase structure and function using PKA as a prototype for this enzyme superfamily -- What we have learned from the overall structural kinome -- Comparison of many protein kinases -- Eukaryotic protein kinase regulation -- Elucidation of general rules of architecture -- Illustration of how PKA is regulated by cAMP and how it is localized to specific macromolecular complexes through scaffold proteins.…”
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Prediction and design of protein structures and interactions

Table of Contents: “…Contents: Modeling of macromolecular interactions -- Conformational sampling -- Docking low-resolution search -- High resolution refinement -- Docking protocol -- Side chain flexibility and modeling -- Ab initio structure prediction -- Computational protein design -- Simultaneous sequence-structure optimization -- Protein interface design -- Properties of free energy landscapes of macromolecules.…”
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Lectures on statistical physics and protein folding by Huang, Kerson, 1928-

Table of Contents: “…. -- Self-assembly. -- Kinetics of protein folding. -- Power laws in protein folding. -- Power laws in protein folding. -- Self-avoiding walk and turbulence. -- Convergent evolution in protein folding. -- Model of energy cascade in a protein molecule.…”
An electronic book accessible through the World Wide Web; click to view

Prediction and design of protein structures and interactions

Table of Contents: “…Contents: Modeling of macromolecular interactions -- Conformational sampling -- Docking low-resolution search -- High resolution refinement -- Docking protocol -- Side chain flexibility and modeling -- Ab initio structure prediction -- Computational protein design -- Simultaneous sequence-structure optimization -- Protein interface design -- Properties of free energy landscapes of macromolecules.…”
Get full text
Series

Phosphorylase and the origin of reversible protein phosphorylation

Table of Contents: “…Contents: A historical account of the discovery of reversible protein phosphorylation -- Video clips of the late Edwin Krebs speaking about our early work -- Reversible protein phosphorylation represents one of the most prevalent mechanism by which cellular events are regulated -- Establishment of the first hormonal cascade of successive enzymatic reactions initiated by cAMP.…”
Get full text
Series

Protein kinase structure, function and regulation

Table of Contents: “…Contents: Overview of protein kinase structure and function using PKA as a prototype for this enzyme superfamily -- What we have learned from the overall structural kinome -- Comparison of many protein kinases -- Eukaryotic protein kinase regulation -- Elucidation of general rules of architecture -- Illustration of how PKA is regulated by cAMP and how it is localized to specific macromolecular complexes through scaffold proteins.…”
Get full text
Series

Three decades of protein phosphorylation and cancer the identification and characterization of the src gene product /

Table of Contents: “…Contents: The avian sarcoma virus genome and its products -- Cellular responses to the viral oncoprotein, Src -- The search for the ASV src gene product -- The RNA genome of avian sarcoma virus -- Searching for Src a function -- Impact of Src protein identification and characterization.…”
Get full text
Series

Biogenesis of cellular iron-sulfur proteins part II, the essential role of mitochondria and the CIA machinery /

Table of Contents: “…Contents: Cytosolic and nuclear Fe/S proteins maturation -- Role of mitochondria in cytosolic and nuclear Fe/S protein biogenesis -- Functions of proteins involved in Fe/S protein biogenesis -- Importance of Fe/S protein biogenesis for genome maintenance.…”
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The functions of the Hsp70 system

Table of Contents: “…Contents: Early steps and problems in nascent protein folding -- Molecular chaperones prevent protein aggregation -- Heat shock protein (molecular chaperone) classes -- Hsp70: characteristics and mechanism of action -- Hsp70 function and cancer (prevention of apoptosis) -- Hsp70 function and viral replication (the polyomaviruses) -- Hsp70 function and protein conformational diseases (ERAD).…”
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The functions of the Hsp70 system

Table of Contents: “…Contents: Early steps and problems in nascent protein folding -- Molecular chaperones prevent protein aggregation -- Heat shock protein (molecular chaperone) classes -- Hsp70: characteristics and mechanism of action -- Hsp70 function and cancer (prevention of apoptosis) -- Hsp70 function and viral replication (the polyomaviruses) -- Hsp70 function and protein conformational diseases (ERAD).…”
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The Myc transcription factor network

Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)

The Myc transcription factor network

Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)

RAS pathway and disease neurofibromatosis and beyond /

Table of Contents: “…Contents: Neurofibromatosis type 1 (NF1) -- NIH diagnostic criteria (Seven criteria for NF1) -- NF1 and the RAS pathway -- NF1 tumour biology -- Neurofibromin deficiency -- Two types of neurofibromas -- Plexiform neurofibroma in the neck and mouth -- Mechanisms of disease -- Mouse models of neurofibroma formation -- Imatinib mesylate treatment -- Clinical aspects of glomus tumours of fingertips -- Gastrointestinal stromal tumours -- MPNST in NF1 -- FDG-PET as a diagnostic tool -- Hotspots for recombination & NF1 microdeletion -- SUZ12-loss -- Cafe-au-lait (CAL) macules -- Skeletal defects in NF1 -- Learning disabilities in NF1 -- Simvastatin treatment for cognitive deficits -- Mosaicism for NF1 mutation -- Diagnostic problems -- SPRED1 mutations & molecular mechanism of Legius syndrome -- The RAS pathway proteins & genetic syndromes (RASopathies).…”
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Molecules nucleation, aggregation and crystallization : beyond medical and other implications /

Table of Contents: “…Carleton Gajdusek -- Gels mimicking antibodies in their selective recognition of proteins and its potential use for protein crystallization / Jan Sedzik ... …”
An electronic book accessible through the World Wide Web; click to view

The quest for the cures the science, stories and struggles behind the next generation of medicines / by Stockwell, Brent R.

Subjects: An electronic book accessible through the World Wide Web; click to view

Copper-oxygen chemistry

Subjects: “…Copper proteins.…”
An electronic book accessible through the World Wide Web; click to view