Search Results - "proteins"

Neuronal calcium sensor proteins calcium sensors and regulators of diverse cellular functions /

Table of Contents: “…Contents: Introduction to calcium sensors -- The neuronal calcium sensor (NCS) protein family -- The calcium/myristoyl switch -- Dynamics of hippocalcin translocation -- Specific localization of NCS proteins -- Functions of NCS-1 -- Hippocalcin in synaptic plasticity -- KChIP proteins in traffic of potassium channels -- Molecular targets of NCS proteins -- The unique features of the NCS family.…”
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Protein homeostasis during ageing

Table of Contents: “…Contents: Ageing and senescent decline -- Protein modifications during ageing -- Main cellular protein homeostasis mechanisms -- Effects of ageing on protein homeostasis -- Regulation of protein synthesis -- Linking protein synthesis and ageing.…”
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Chaperonin-mediated protein folding part 1 /

Table of Contents: “…Contents: Chaperonin-mediated protein folding by GroEL/GroES -- Folding of newly-translated protein -- Currently known Molecular chaperones (including the Heat shock protein Hsp group) -- Recognition of non native proteins by Hsps and formation of aggregates -- Aggregates and neurodegenerative disease -The discovery of the chaperonin-mediated folding -- The structure of the GroES/GroeEL chaperonin class of molecular chaperones -- The steps of polypeptide binding and folding -- The action of ATP binding and hydrolysis in driving the rings of the machine through cycles of binding and release cycle.…”
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Chaperonin-mediated protein folding part 2 /

Table of Contents: “…Contents: Chaperonin-mediated protein folding by GroEL/GroES -- Folding of newly-translated protein -- Currently known Molecular chaperones (including the Heat shock protein Hsp group) -- Recognition of non native proteins by Hsps and formation of aggregates -- Aggregates and neurodegenerative disease -The discovery of the chaperonin-mediated folding -- The structure of the GroES/GroeEL chaperonin class of molecular chaperones -- The steps of polypeptide binding and folding -- The action of ATP binding and hydrolysis in driving the rings of the machine through cycles of binding and release cycle.…”
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AMP-activated protein kinase regulating cellular and whole body energy balance /

Table of Contents: “…Contents: AMPK-activated protein kinase -- Role as a cellular energy sensor -- Role in lower eukaryotes -- Metabolic pathways targeted by AMPK -- Cytokines, drugs (including metformin) and xenobiotics that target AMPK -- Identification of upstream kinases -- Regulation by AMP, ATP and calcium ions -- Potential of AMPK as a drug target in cancer…”
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Structure and mechanisms of protein phosphatases

Table of Contents: “…Contents: Reversible protein phosphorylation -- Classification of protein phosphatases -- Protein tyrosine phosphatase family, structure of PTP1B, catalytic mechanism, basis for pTyr specificity, recognition of IRK, regulation by ROS and cyclic sulphenamide -- Dual specificity phosphatases -- Eya protein tyrosine phosphatases -- PPP family of Ser/Thr phosphatases, structure of PP1, catalytic mechanism, inhibition by okadaic acid and microcystin, targeting subunits, PP2A, PP2B, PP5 -- PPM family of Ser/Thr phosphatases, structure, catalytic mechanism -- Summary.…”
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Protein folding inside the cell macromolecular crowding and protein aggregation /

Table of Contents: “…Contents: The principle of protein self-assembly -- Discovery of proteins binding to newly synthesized polypeptides -- Discovery of the chaperonins -- Origins of the molecular chaperone concept -- Replacement of spontaneous self-assembly by assisted self-assembly -- Protein aggregation as a universal cellular problem -- Macromolecular crowding and its effects on reaction rates and association constants -- Stimulation of aggregation by crowding -- How chaperones combat aggregation -- Definition of molecular chaperones -- The chaperone function.…”
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The protein C-Thrombomodulin mechanism regulating multiple biological systems /

Table of Contents: “…Contents: Protein C and thrombomodulin -- Mechanisms of action in coagulation and inflammation -- Diagnostic and therapeutic insights.…”
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Mechanisms of protein folding reactions

Table of Contents: “…Contents: History of protein folding -- Origin of complexity in protein folding kinetics -- Slow reactions coupled to folding -- Prolyl isomerization -- Non-prolyl isomerization -- Association reactions -- Detection of folding intermediates -- Discrimination between different kinetic mechanisms -- Folding of multi-domain proteins.…”
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Kinetic analysis of protein activity

Table of Contents: “…Contents: Thermodynamics vs. kinetics -- Enzyme catalysis -- Conventional and rapid kinetic methods -- Equilibrium and steady-state approaches -- The phases of an enzymatic reaction -- Graphical and statistical analysis -- Enzyme inhibition -- The importance of kinetics for protein activity.…”
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G-protein coupled receptors hormone membrane receptors /

Table of Contents: “…Contents: Rhodopsin: prototype GPCR -- Major classes of GPCRs: rhodopsin-like, glucagon-like, mGlu-like -- Experimental approaches to study GPCR structure -- Rhodopsin crystal structure -- GPCR activation -- Signal trafficking -- Receptor RNA processing/isoforms -- GRKs/arrestin -- Rhodopsin dimerization -- RAMPs: receptor activity modifying protein -- RAMPs, heterodimers and expression -- GPCRs and disease -- Thyroxine and thyrotropin…”
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Polydactyl zinc finger proteins software and hardware for genomes /

Table of Contents: “…Contents: Development of a universal system for gene regulation -- A diversity of recognition domains -- Phage display -- Targeted endogenous gene regulation in cells and organisms -- The specificity issue and genome size -- Genomic specificity requires polydactyl proteins -- Transcription factor libraries: a powerful new strategy -- Cutting and pasting genes and genomes -- Zinc finger enzymes and designer epigenetic modifications -- Zinc finger nucleases: scissors for genome surgery -- Recombinases -- Gene delivery vehicles.…”
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Yeast prions and protein chaperones a help or a hindrance? /

Table of Contents: “…Contents: Role of protein chaperones in protein folding -- Yeast prions as amyloid forms of cellular proteins -- Requirement of chaperone machinery for prion propagation -- Chaperone mutants adversely affect prions and provide insight into chaperone/amyloid interactions.…”
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Nutritional evaluation of protein foods /

Structural aspects of protein synthesis by Liljas, Anders

Subjects: “…Proteins Synthesis.…”
An electronic book accessible through the World Wide Web; click to view

The physical foundation of protein architecture by Saitō, Nobuhiko

Subjects: “…Proteins Structure.…”
An electronic book accessible through the World Wide Web; click to view

Bone morphogenetic protein and collagen an advances in tissue banking specialist publication /

Subjects: “…Bone morphogenetic proteins.…”
An electronic book accessible through the World Wide Web; click to view

Protein folding inside the cell macromolecular crowding and protein aggregation /

Table of Contents: “…Contents: The principle of protein self-assembly -- Discovery of proteins binding to newly synthesized polypeptides -- Discovery of the chaperonins -- Origins of the molecular chaperone concept -- Replacement of spontaneous self-assembly by assisted self-assembly -- Protein aggregation as a universal cellular problem -- Macromolecular crowding and its effects on reaction rates and association constants -- Stimulation of aggregation by crowding -- How chaperones combat aggregation -- Definition of molecular chaperones -- The chaperone function.…”
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Neuronal calcium sensor proteins calcium sensors and regulators of diverse cellular functions /

Table of Contents: “…Contents: Introduction to calcium sensors -- The neuronal calcium sensor (NCS) protein family -- The calcium/myristoyl switch -- Dynamics of hippocalcin translocation -- Specific localization of NCS proteins -- Functions of NCS-1 -- Hippocalcin in synaptic plasticity -- KChIP proteins in traffic of potassium channels -- Molecular targets of NCS proteins -- The unique features of the NCS family.…”
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The protein C-Thrombomodulin mechanism regulating multiple biological systems /

Table of Contents: “…Contents: Protein C and thrombomodulin -- Mechanisms of action in coagulation and inflammation -- Diagnostic and therapeutic insights.…”
Get full text
Series