Search Results - "proteins"

Glucose-6-Phosphate dehydrogenase deficiency

Table of Contents: “…Contents: G6PD and X-chromosome -- Genetics -- Protein structure and function -- G6PD and neutrophil function/inflammation -- Role of G6PD in diabetes mellitus -- Hypertension -- G6PD modulates vascular oxidant stress -- Angiogenesis is regulated by G6PD activity -- G6PD and vascular reactivity -- G6PD, cardiomyocytes and ischemia-reperfusion.…”
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Pleiotropic and epistatic genes in sickle cell anemia

Subjects: “…Protein Conformation.…”
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The biology and pathobiology of Von Willebrand factor

Subjects: “…Protein Conformation.…”
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Pumps, channels, and transporters : methods of functional analysis /

Subjects: “…Carrier proteins.…”
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Understanding protein variability through functional analysis of random mutagenesis

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Understanding protein variability through functional analysis of random mutagenesis

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Amyloidosis disease caused by amyloid /

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Chaperone mechanisms in cellular protein folding

Table of Contents: “…Contents: The effect of protein aggregation on productive protein folding -- The function of GroEL and GroES as a folding cage for proteins -- Changes in energy landscape within the folding cage -- Cooperation of different chaperone systems in folding pathways: Hsp70 and chaperonins -- Binding of the Hsp70 homologue protein, DnaK, to newly-synthesized polypeptides -- The role of chaperone mechanisms in toxicity suppression of misfolded disease causing proteins -- Potential uses of the chaperone mechanisms in disease therapeutics.…”
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Protein aggregation, metals and oxidative stress in neurodegenerative diseases

Table of Contents: “…Contents: Introduction to protein conformational brain diseases -- Alzheimer's disease, A-beta and tau -- A-beta oligomers and toxicity -- A-beta generates hydrogen peroxide -- Results from experiments using electron spin resonance spectroscopy -- Parkinson's disease -- Generation of hydrogen peroxide from alpha synuclein, toxic fragments of the prion protein and the familial British dementia peptide -- Early oligomers appear to generate hydrogen peroxide -- Huntington's disease -- Protein aggregates could be protective -- Potential common toxic pathway for these brain diseases.…”
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Novel proteins from designed combinatorial libraries

Table of Contents: “…Contents: Novel proteins can be devised using either rational/computational approaches or random/combinatorial methods -- Description of a hybrid approach that combines rational and combinatorial methods: libraries of novel proteins -- Combinatorial diversity -- Random vs. focused libraries -- Amphiphilic alpha-helices and beta-strands -- Binary patterning of polar and non-polar amino acids -- Genetic encoding of combinatorial mixtures of polar and non-polar amino acids -- Design of libraries of novel 4-helix bundles -- Library construction and expression in vivo -- Dynamic vs. wellordered protein structures -- Second generation libraries -- Biophysical characterization -- Solution structure of native-like 4-helix bundle proteins from designed libraries -- Functionally active proteins including cofactor binding proteins, peroxidases and esterases -- Designed libraries of beta sheet proteins: amyloid-like fibrils, monomeric beta-sheet proteins and novel biomaterials.…”
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Novel proteins from designed combinatorial libraries

Table of Contents: “…Contents: Novel proteins can be devised using either rational/computational approaches or random/combinatorial methods -- Description of a hybrid approach that combines rational and combinatorial methods: libraries of novel proteins -- Combinatorial diversity -- Random vs. focused libraries -- Amphiphilic alpha-helices and beta-strands -- Binary patterning of polar and non-polar amino acids -- Genetic encoding of combinatorial mixtures of polar and non-polar amino acids -- Design of libraries of novel 4-helix bundles -- Library construction and expression in vivo -- Dynamic vs. wellordered protein structures -- Second generation libraries -- Biophysical characterization -- Solution structure of native-like 4-helix bundle proteins from designed libraries -- Functionally active proteins including cofactor binding proteins, peroxidases and esterases -- Designed libraries of beta sheet proteins: amyloid-like fibrils, monomeric beta-sheet proteins and novel biomaterials.…”
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Preparative chromatography for separation of proteins /

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Transport and delivery of neurotrophic peptides and proteins across the BBB

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Mechanism of chaperone action of small heat shock proteins

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Molecular chaperones and handling of abnormal proteins in neurodegenerative disorders

Table of Contents: “…Contents: Aggregation of proteins associated with neurodegenerative disorders -- Mechanisms of aggresome formation -- Suppression of the heat shock response in aging and neurodegeneration -- Role of heat shock proteins in suppression of apoptosis and senescence programs.…”
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Transport and delivery of neurotrophic peptides and proteins across the BBB

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Mechanism of chaperone action of small heat shock proteins

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Molecular chaperones and handling of abnormal proteins in neurodegenerative disorders

Table of Contents: “…Contents: Aggregation of proteins associated with neurodegenerative disorders -- Mechanisms of aggresome formation -- Suppression of the heat shock response in aging and neurodegeneration -- Role of heat shock proteins in suppression of apoptosis and senescence programs.…”
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Mechanism of chaperone action of small heat shock proteins

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Molecular chaperones and handling of abnormal proteins in neurodegenerative disorders

Table of Contents: “…Contents: Aggregation of proteins associated with neurodegenerative disorders -- Mechanisms of aggresome formation -- Suppression of the heat shock response in aging and neurodegeneration -- Role of heat shock proteins in suppression of apoptosis and senescence programs.…”
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