Search Results - "proteins"

Hepatic encephalopathy in cirrhosis a disorder of glial-neuronal signalling /

Table of Contents: “…Contents: Classification of hepatic encephalopathy -- Hepatic encephalopathy in cirrhosis -- Transjugular intrahepatic portosystemic shunt (TIPS) -- Hepatic encephalopathy post-TIPS -- Neuropathology of hepatic encephalopathy in chronic liver failure -- Cirrhosis-related Parkinsonism -- PET studies in cirrhosis -- Neuroinflammation and hepatic encephalopathy in cirrhosis -- Systemic inflammatory response syndrome (SIRS) in cirrhosis -- Translocator protein and hepatic encephalopathy in cirrhosis -- Modulatory site for neurosteroids -- Prevention and treatment of hepatic encephalopathy in cirrhosis -- Emerging new therapeutic approaches.…”
Get full text
Series

Vascular cell signaling by membrane estrogen receptors

Table of Contents: “…Contents: Endothelium -- Endothelial dysfunction -- Estrogen-mediated cardiovascular protection and leukocyte-endothelial cell adhesion -- Estrogen as a determinant of cardiovascular risk -- Effects of estrogen on the cardiovascular system -- Rapid EC activation effects of estrogen -- Effect of estradiol on NO release from human endothelial cells -- Estrogen receptor knockout (ERKO) mouse cardiovascular studies -- Palmitoylation is required for membrane translocation of ER46 -- Akt/protein kinase B -- Endothelial homeostasis -- Kronos early estrogen prevention study.…”
Get full text
Series

Roles for molecular chaperones in cystic fibrosis

Table of Contents: “…Contents: Cystic fibrosis is a fatal homozygous recessive disorder -- Caused primarily by misfolding of mutant forms of cystic fibrosis transmembrane conductance regulator (CFTR) -- The folding defects in mutant CFTR are detected by protein quality control machines in the endoplasmic reticulum that target mutant CFTR for premature degradation -- Small molecules that are being developed as drugs to treat cystic fibrosis enable mutant CFTR to avoid recognition by the endoplasmic reticulum quality control system and function at the cell surface.…”
Get full text
Series

Chemical synthesis of peptides and peptide libraries

Table of Contents: “…Contents: Peptide and protein synthesis is the most robust of all synthetic chemistries -- Very large combinatorial libraries with billions of different peptides are possible -- Highly constrained peptides with specific secondary (phi/psi space) and tertiary (chi space) structures can be designed and synthesized -- Peptides stable to proteolytic degradation and able to cross BBB can be synthesized -- Peptides designed and synthesized with potent and selective bioactivities -- Many excellent drugs -- Peptide synthesis a critical tool for all aspects of chemical biology.…”
Get full text
Series

Salmonellae molecular basis of infection /

Table of Contents: “…Contents: Salmonellae -- Gram-negative bacteria that cause gastroenteritis and systemic disease or enteric fever -- Mechanisms of bacterial pathogenesis include: sensing host environments through a specific receptor, remodeling the bacterial surface, and altering host cells processes -- A receptor that recognizes antimicrobial peptides and low pH -- Regulation of the structure of lipopolysaccharide, and alteration of the Salmonella-containing phagosome by use of a specialized secretion system that functions to accomplish protein transport to the mammalian cell cytoplasm.…”
Get full text
Series

Chemical synthesis of peptides and peptide libraries

Table of Contents: “…Contents: Peptide and protein synthesis is the most robust of all synthetic chemistries -- Very large combinatorial libraries with billions of different peptides are possible -- Highly constrained peptides with specific secondary (phi/psi space) and tertiary (chi space) structures can be designed and synthesized -- Peptides stable to proteolytic degradation and able to cross BBB can be synthesized -- Peptides designed and synthesized with potent and selective bioactivities -- Many excellent drugs -- Peptide synthesis a critical tool for all aspects of chemical biology.…”
Get full text
Series

Vascular cell signaling by membrane estrogen receptors

Table of Contents: “…Contents: Endothelium -- Endothelial dysfunction -- Estrogen-mediated cardiovascular protection and leukocyte-endothelial cell adhesion -- Estrogen as a determinant of cardiovascular risk -- Effects of estrogen on the cardiovascular system -- Rapid EC activation effects of estrogen -- Effect of estradiol on NO release from human endothelial cells -- Estrogen receptor knockout (ERKO) mouse cardiovascular studies -- Palmitoylation is required for membrane translocation of ER46 -- Akt/protein kinase B -- Endothelial homeostasis -- Kronos early estrogen prevention study.…”
Get full text
Series

Roles for molecular chaperones in cystic fibrosis

Table of Contents: “…Contents: Cystic fibrosis is a fatal homozygous recessive disorder -- Caused primarily by misfolding of mutant forms of cystic fibrosis transmembrane conductance regulator (CFTR) -- The folding defects in mutant CFTR are detected by protein quality control machines in the endoplasmic reticulum that target mutant CFTR for premature degradation -- Small molecules that are being developed as drugs to treat cystic fibrosis enable mutant CFTR to avoid recognition by the endoplasmic reticulum quality control system and function at the cell surface.…”
Get full text
Series

Salmonellae molecular basis of infection /

Table of Contents: “…Contents: Salmonellae -- Gram-negative bacteria that cause gastroenteritis and systemic disease or enteric fever -- Mechanisms of bacterial pathogenesis include: sensing host environments through a specific receptor, remodeling the bacterial surface, and altering host cells processes -- A receptor that recognizes antimicrobial peptides and low pH -- Regulation of the structure of lipopolysaccharide, and alteration of the Salmonella-containing phagosome by use of a specialized secretion system that functions to accomplish protein transport to the mammalian cell cytoplasm.…”
Get full text
Series

Vascular cell signaling by membrane estrogen receptors

Table of Contents: “…Contents: Endothelium -- Endothelial dysfunction -- Estrogen-mediated cardiovascular protection and leukocyte-endothelial cell adhesion -- Estrogen as a determinant of cardiovascular risk -- Effects of estrogen on the cardiovascular system -- Rapid EC activation effects of estrogen -- Effect of estradiol on NO release from human endothelial cells -- Estrogen receptor knockout (ERKO) mouse cardiovascular studies -- Palmitoylation is required for membrane translocation of ER46 -- Akt/protein kinase B -- Endothelial homeostasis -- Kronos early estrogen prevention study.…”
Get full text
Series

Roles for molecular chaperones in cystic fibrosis

Table of Contents: “…Contents: Cystic fibrosis is a fatal homozygous recessive disorder -- Caused primarily by misfolding of mutant forms of cystic fibrosis transmembrane conductance regulator (CFTR) -- The folding defects in mutant CFTR are detected by protein quality control machines in the endoplasmic reticulum that target mutant CFTR for premature degradation -- Small molecules that are being developed as drugs to treat cystic fibrosis enable mutant CFTR to avoid recognition by the endoplasmic reticulum quality control system and function at the cell surface.…”
Get full text
Series

Chemical synthesis of peptides and peptide libraries

Table of Contents: “…Contents: Peptide and protein synthesis is the most robust of all synthetic chemistries -- Very large combinatorial libraries with billions of different peptides are possible -- Highly constrained peptides with specific secondary (phi/psi space) and tertiary (chi space) structures can be designed and synthesized -- Peptides stable to proteolytic degradation and able to cross BBB can be synthesized -- Peptides designed and synthesized with potent and selective bioactivities -- Many excellent drugs -- Peptide synthesis a critical tool for all aspects of chemical biology.…”
Get full text
Series

Salmonellae molecular basis of infection /

Table of Contents: “…Contents: Salmonellae -- Gram-negative bacteria that cause gastroenteritis and systemic disease or enteric fever -- Mechanisms of bacterial pathogenesis include: sensing host environments through a specific receptor, remodeling the bacterial surface, and altering host cells processes -- A receptor that recognizes antimicrobial peptides and low pH -- Regulation of the structure of lipopolysaccharide, and alteration of the Salmonella-containing phagosome by use of a specialized secretion system that functions to accomplish protein transport to the mammalian cell cytoplasm.…”
Get full text
Series

Gene discovery for disease models

Table of Contents: “…Introduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models.…”
An electronic book accessible through the World Wide Web; click to view

Innate immunity in the intestine in health and disease

Table of Contents: “…Contents: Mucosal tissues of the human body -- Intestinal pathogens -- Mucosal immune system: distinctive features -- Gut-associated lymphoid tissue (GALT) -- Structure of the GALT: small and large intestine -- Mucus, a key protective barrier -- Antimicrobial proteins protect the epithelium -- Epithelial cell transcytosis of secretory IgA -- Uptake and transport of antigen by M cells -- Microbial sensing regulates intestinal homeostasis -- Sensing of microbes occurs through PRR -- MyD88 signals in IEC -- Intestinal macrophages are anti-inflammatory -- Intestinal DC 'conditioning' -- Inflammatory bowel disease (IBD) -- Genome-wide association studies -- The enigma of NOD2 and Crohn's disease -- NOD2 signaling in response to bacterial MDP -- NOD2 signaling regulates myeloid cell function -- Autophagy also regulates IEC and myeloid cells -- MyD88 activation drives intestinal inflammation -- Haematopoeitic MyD88 signals -- Immune dysregulation in chronic inflammation -- Innate lymphoid cells (ILC) drive innate IBD -- Leukocyte populations and intestinal homeostasis.…”
Get full text
Series

A Q&A approach to organic chemistry / by Smith, Michael, 1946 October 17-

Taylor & Francis
OCLC metadata license agreement

Molecular genetics of bacteria / by Snyder, Larry

Table of Contents: “…The bacterial chromosome : DNA structure, replication, and segregation -- Bacterial gene expression : transcription, translation, and protein folding -- Bacterial genetic analysis : fundamentals and current approaches -- Plasmids -- Conjugation -- Transformation -- Lytic bacteriophages : development, genetics, and generalized transduction -- Lysogeny : the lambda paradigm and the role of lysogenic conversion in bacterial pathogenesis -- Transposition, site-specific recombination, and families of recombinases -- Molecular mechanisms of homologous recombination -- DNA repair and mutagenesis -- Regulation of gene expression: genes and operons -- Global regulation : regulons and stimulons -- Bacterial cell biology and development.…”
An electronic book accessible through the World Wide Web; click to view

Hepatic encephalopathy in acute liver failure a primary neurogliopathy /

Table of Contents: “…Contents: Classification of hepatic encephalopathy -- Acute liver failure -- Neuropathology of Acute liver failure -- Pathogenesis of hepatic encephalopathy in Acute liver failure: key role of ammonia -- Arterial NH3: risk factor of intracranial hypertension -- Selective gene expression alterations in Acute liver failure -- Glial fibrillary acidic protein (GFAP) -- Glutamate transporter EAAT-2 -- Extracellular brain glutamate and neurological status -- Systemic inflammation in Acute liver failure -- Brain cytokines in Acute liver failure -- Therapeutic implications.…”
Get full text
Series

Chemical file formats and line notations

Table of Contents: “…Contents: Chemical structure representation -- Atom positions in space -- Redundant & Non-redundant connection tables -- Atom numbering -- MDL/Symyx molfile (.mol) -- Protein Data Bank (PDB) format -- Daylight SMILES -- Molecular tree and line notation -- Chemical structure elucidation -- 13C-NMR spectroscopy -- HOSE code -- Spectra prediction and spectra interpretation -- Overlaying substructures -- InChI -- MARKUSH structures -- Format conversion -- OO programming -- Unified Modelling Language (UML) -- Chemistry Development Kit (CDK).…”
Get full text
Series

Paneth cells in innate immunity and inflammatory bowel disease

Table of Contents: “…Contents: Position and structure of Paneth cells -- Produce diverse protein products -- Ultrastructure -- Lysozyme -- Paneth cell defensins -- Salmonella infection -- Antimicrobial function -- Zinc -- IgA -- Effects of lineage ablation -- TNFalfa -- Expression of immune-related genes -- Potential role in human disease -- Are Paneth cells involved in the pathogenesis of IBD? …”
Get full text
Series