Search Results - "oxidative stress"

Protein homeostasis in mitochondria chaperones and proteases of the mitochondrial matrix /

Table of Contents: “…Contents: Protein homeostasis in mitochondria: the role of chaperones and proteases -- Principles of mitochondrial protein homeostasis -- Protein quality control in the matrix compartment -- Substrate selectivity of the mitochondrial protease Pim1 -- Proteomic analysis of mitochondrial protein turnover -- Proteome alterations under oxidative stress -- Identification of aggregation-prone polypeptides -- Protective effects of chaperones -- Cooperation of Hsp78 and Pim1 in removal of aggregated polypeptides.…”
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Protein homeostasis in mitochondria chaperones and proteases of the mitochondrial matrix /

Table of Contents: “…Contents: Protein homeostasis in mitochondria: the role of chaperones and proteases -- Principles of mitochondrial protein homeostasis -- Protein quality control in the matrix compartment -- Substrate selectivity of the mitochondrial protease Pim1 -- Proteomic analysis of mitochondrial protein turnover -- Proteome alterations under oxidative stress -- Identification of aggregation-prone polypeptides -- Protective effects of chaperones -- Cooperation of Hsp78 and Pim1 in removal of aggregated polypeptides.…”
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Glucose-6-Phosphate dehydrogenase deficiency

Table of Contents: “…Contents: G6PD and X-chromosome -- Genetics -- Protein structure and function -- G6PD and neutrophil function/inflammation -- Role of G6PD in diabetes mellitus -- Hypertension -- G6PD modulates vascular oxidant stress -- Angiogenesis is regulated by G6PD activity -- G6PD and vascular reactivity -- G6PD, cardiomyocytes and ischemia-reperfusion.…”
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Glucose-6-Phosphate dehydrogenase deficiency

Table of Contents: “…Contents: G6PD and X-chromosome -- Genetics -- Protein structure and function -- G6PD and neutrophil function/inflammation -- Role of G6PD in diabetes mellitus -- Hypertension -- G6PD modulates vascular oxidant stress -- Angiogenesis is regulated by G6PD activity -- G6PD and vascular reactivity -- G6PD, cardiomyocytes and ischemia-reperfusion.…”
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Glucose-6-Phosphate dehydrogenase deficiency

Table of Contents: “…Contents: G6PD and X-chromosome -- Genetics -- Protein structure and function -- G6PD and neutrophil function/inflammation -- Role of G6PD in diabetes mellitus -- Hypertension -- G6PD modulates vascular oxidant stress -- Angiogenesis is regulated by G6PD activity -- G6PD and vascular reactivity -- G6PD, cardiomyocytes and ischemia-reperfusion.…”
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Female hepatology favorable role of female factors in chronic liver disease / by Shimizu, Ichiro, 1958-

Table of Contents: “…Liver cancer is predominant in men and postmenopausal women -- Chronic hepatitis C and B progress more slowly in females than males -- Hepatic fibrosis and oxidative stress -- Female sex hormones in hepatic fibrosis -- Ms, you can never become an 'iron lady' -- Immune response is affected by estrogens, progesterone and testosterone -- Females and non-alcoholic fatty liver disease -- 'Female paradox' in alcoholic liver disease -- Autoimmune liver diseases in females -- Are estrogens useful as a therapeutic drug for chronic liver disease? …”
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The calcium saga a matter of life and death /

Table of Contents: “…Contents: Calcium and cytotoxicity -- Indicator dyes for calcium detection -- Alteration of thiol and calcium homeostasis causes cell death -- Oxidative stress and thiol modification impair calcium storage and extrusion -- Calcium ATPase -- The calcium and thiol hypothesis of cell death -- Calcium as a second messenger -- Calcium is involved in different cell death paradigms -- Nuclear calcium transport -- Intracellular calcium distribution -- PMCAs: vital membrane calcium transporters -- PMCAs are degraded during cell death -- Non-degradable PMCAs protect against cell death -- Mechanisms of calcium deregulation during cell death -- NCX3 and calpains in calcium maintenance -- Prevention of excitotoxicity via calcium management.…”
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The calcium saga a matter of life and death /

Table of Contents: “…Contents: Calcium and cytotoxicity -- Indicator dyes for calcium detection -- Alteration of thiol and calcium homeostasis causes cell death -- Oxidative stress and thiol modification impair calcium storage and extrusion -- Calcium ATPase -- The calcium and thiol hypothesis of cell death -- Calcium as a second messenger -- Calcium is involved in different cell death paradigms -- Nuclear calcium transport -- Intracellular calcium distribution -- PMCAs: vital membrane calcium transporters -- PMCAs are degraded during cell death -- Non-degradable PMCAs protect against cell death -- Mechanisms of calcium deregulation during cell death -- NCX3 and calpains in calcium maintenance -- Prevention of excitotoxicity via calcium management.…”
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The calcium saga a matter of life and death /

Table of Contents: “…Contents: Calcium and cytotoxicity -- Indicator dyes for calcium detection -- Alteration of thiol and calcium homeostasis causes cell death -- Oxidative stress and thiol modification impair calcium storage and extrusion -- Calcium ATPase -- The calcium and thiol hypothesis of cell death -- Calcium as a second messenger -- Calcium is involved in different cell death paradigms -- Nuclear calcium transport -- Intracellular calcium distribution -- PMCAs: vital membrane calcium transporters -- PMCAs are degraded during cell death -- Non-degradable PMCAs protect against cell death -- Mechanisms of calcium deregulation during cell death -- NCX3 and calpains in calcium maintenance -- Prevention of excitotoxicity via calcium management.…”
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Sex hormones development, regulation and disorders /

Table of Contents: “…Sex hormones and hypothalamus / Roxana Carbó, Martín Martínez -- Non reproductive effects of sex hormones and the cardiovascular system / Guadalupe Baños, Israel Pérez-Torres -- Sex hormone receptors in metabolic syndrome / Israel Pérez-Torres, Guadalupe Baños de Maccarthy -- Antiestrogen or estrogen as anticancer drug / Zsuzsanna Suba -- Sex hormones and oxidative stress in metabolic syndrome / El Hafidi Mohammed, Angelica Ruiz Ramírez -- Sources, presence, analysis, and fate of steroid sex hormones in freshwater ecosystems : a review / Robert B. …”
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Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part II /

Table of Contents: “…Contents: Pharmacokinetics and TD: a look at the cytochrome P450 system -- Oxidative stress and TD: a look at free radicals and the superoxide dismutase genes -- Psychiatric pharmacogenetics as cleaner complex phenotypes -- Neuroimaging in pharmacogenetics: towards even cleaner phenotypes -- Complex traits and new statistical models for looking at multigene interactions with continuous variables -- Recommendations for future studies: bringing pharmacogenetics from "Bench to Bedside" and from "Bedside back to Bench" -- Onward towards individualized pharmacotherapy.…”
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The endoplasmic reticulum the unfolded protein response /

Table of Contents: “…Contents: The secretory pathway -- Factor VIII expression induces ER stress -- Protein folding: the ultimate and most error prone step in gene expression -- The "unfolded protein response" (UPR) ensures fidelity of protein folding -- UPR signaling response -- Activation of the UPR -- Stress signaling from the ER -- Role of eIF2 in translation initiation -- Translation initiation response to external stimuli -- eIF2a phosphorylation is required for UPR -- Wolcott-Rallison syndrome -- Plasma cell differentiation requires ER expansion -- Roles of IRE1a/XBP1 in lymphocyte development -- ER-stress-induced transcription through regulated intramembrane proteolysis (RIP) -- CREBH and ATF6 -- ER-stress-induced apoptosis -- ER stress and oxidative stress -- UPR-induced alterations in gene expression.…”
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Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part II /

Table of Contents: “…Contents: Pharmacokinetics and TD: a look at the cytochrome P450 system -- Oxidative stress and TD: a look at free radicals and the superoxide dismutase genes -- Psychiatric pharmacogenetics as cleaner complex phenotypes -- Neuroimaging in pharmacogenetics: towards even cleaner phenotypes -- Complex traits and new statistical models for looking at multigene interactions with continuous variables -- Recommendations for future studies: bringing pharmacogenetics from "Bench to Bedside" and from "Bedside back to Bench" -- Onward towards individualized pharmacotherapy.…”
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The endoplasmic reticulum the unfolded protein response /

Table of Contents: “…Contents: The secretory pathway -- Factor VIII expression induces ER stress -- Protein folding: the ultimate and most error prone step in gene expression -- The "unfolded protein response" (UPR) ensures fidelity of protein folding -- UPR signaling response -- Activation of the UPR -- Stress signaling from the ER -- Role of eIF2 in translation initiation -- Translation initiation response to external stimuli -- eIF2a phosphorylation is required for UPR -- Wolcott-Rallison syndrome -- Plasma cell differentiation requires ER expansion -- Roles of IRE1a/XBP1 in lymphocyte development -- ER-stress-induced transcription through regulated intramembrane proteolysis (RIP) -- CREBH and ATF6 -- ER-stress-induced apoptosis -- ER stress and oxidative stress -- UPR-induced alterations in gene expression.…”
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Pharmacogenetics of tardive dyskinesia a "Movement" towards individualized therapy. Part II /

Table of Contents: “…Contents: Pharmacokinetics and TD: a look at the cytochrome P450 system -- Oxidative stress and TD: a look at free radicals and the superoxide dismutase genes -- Psychiatric pharmacogenetics as cleaner complex phenotypes -- Neuroimaging in pharmacogenetics: towards even cleaner phenotypes -- Complex traits and new statistical models for looking at multigene interactions with continuous variables -- Recommendations for future studies: bringing pharmacogenetics from "Bench to Bedside" and from "Bedside back to Bench" -- Onward towards individualized pharmacotherapy.…”
Get full text
Series

The endoplasmic reticulum the unfolded protein response /

Table of Contents: “…Contents: The secretory pathway -- Factor VIII expression induces ER stress -- Protein folding: the ultimate and most error prone step in gene expression -- The "unfolded protein response" (UPR) ensures fidelity of protein folding -- UPR signaling response -- Activation of the UPR -- Stress signaling from the ER -- Role of eIF2 in translation initiation -- Translation initiation response to external stimuli -- eIF2a phosphorylation is required for UPR -- Wolcott-Rallison syndrome -- Plasma cell differentiation requires ER expansion -- Roles of IRE1a/XBP1 in lymphocyte development -- ER-stress-induced transcription through regulated intramembrane proteolysis (RIP) -- CREBH and ATF6 -- ER-stress-induced apoptosis -- ER stress and oxidative stress -- UPR-induced alterations in gene expression.…”
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Liver cancer causes, diagnosis and treatment /

Table of Contents: “….] -- Chronic hepatitis C and liver cancer : significance of oxidative stress-induced chromosomal breakage / Ingrid Emerit -- Imaging hepatocellular carcinoma using positron emission tomography / Zhenghong Lee ... …”
An electronic book accessible through the World Wide Web; click to view

Pleiotropic and epistatic genes in sickle cell anemia

Table of Contents: “…Contents: Determination of pleiotropic genes -- Search for polymorphic genes among the pleiotropic genes as candidates for epistasis -- Known epistatic effects -- Kidney pathology in sickle cell disease -- Renal disease epidemiology -- Panoply of transgenic mice -- Involvement of metabolic pathways in constitutive chronic kidney damage in Tx mice -- Hypoxia -- Mediators of oxidative stress -- Up and down regulated genes -- HO- 1 histopathology -- The effect of sickle red blood cell adhesion on gene expression in PAF pre-treated microcirculatory bed -- Von Willebrand factor (vWF) and sickle cell anemia -- vWF, shear stress and sickle cell anaemia -- Epistatic genes may open new therapeutic strategies for SS disease -- PAF induces the up-regulation of a number of genes that have the capacity of protecting the endothelium, stem cells and other hematopoetic precursors.…”
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Pleiotropic and epistatic genes in sickle cell anemia

Table of Contents: “…Contents: Determination of pleiotropic genes -- Search for polymorphic genes among the pleiotropic genes as candidates for epistasis -- Known epistatic effects -- Kidney pathology in sickle cell disease -- Renal disease epidemiology -- Panoply of transgenic mice -- Involvement of metabolic pathways in constitutive chronic kidney damage in Tx mice -- Hypoxia -- Mediators of oxidative stress -- Up and down regulated genes -- HO- 1 histopathology -- The effect of sickle red blood cell adhesion on gene expression in PAF pre-treated microcirculatory bed -- Von Willebrand factor (vWF) and sickle cell anemia -- vWF, shear stress and sickle cell anaemia -- Epistatic genes may open new therapeutic strategies for SS disease -- PAF induces the up-regulation of a number of genes that have the capacity of protecting the endothelium, stem cells and other hematopoetic precursors.…”
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Series

Pleiotropic and epistatic genes in sickle cell anemia

Table of Contents: “…Contents: Determination of pleiotropic genes -- Search for polymorphic genes among the pleiotropic genes as candidates for epistasis -- Known epistatic effects -- Kidney pathology in sickle cell disease -- Renal disease epidemiology -- Panoply of transgenic mice -- Involvement of metabolic pathways in constitutive chronic kidney damage in Tx mice -- Hypoxia -- Mediators of oxidative stress -- Up and down regulated genes -- HO- 1 histopathology -- The effect of sickle red blood cell adhesion on gene expression in PAF pre-treated microcirculatory bed -- Von Willebrand factor (vWF) and sickle cell anemia -- vWF, shear stress and sickle cell anaemia -- Epistatic genes may open new therapeutic strategies for SS disease -- PAF induces the up-regulation of a number of genes that have the capacity of protecting the endothelium, stem cells and other hematopoetic precursors.…”
Get full text
Series