Search Results - "influenza"

Emerging or newly discovered viral causes of acute lower respiratory tract infections worldwide

Table of Contents: “…Contents: Lower respiratory infections -- Global distribution of mortality among children -- Community-acquired pneumonia in children -- Causes of severe acute respiratory infections -- The three classifications of viruses -- Zoonosis: new viruses -- Coronaviruses and SARS -- Avian influenza -- Hendra virus -- Nipah virus -- Emergence of new zoonotic viruses -- Newly recognized causes of ALRI -- Rhinovirus -- Para-influenza 4 -- Coronaviruses NL63 & HKU1 -- Newly discovered viruses -- Human metapneumovirus -- Human bocavirus -- Polyomaviruses, WU and KI -- Mimivirus -- Importance of newly discovered ALRTI causes -- Requirements for further research.…”
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Understanding statistics in epidemics and pandemics lessons learned from COVID-19 /

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The COVID-19 outbreak an update on the SARS-CoV-2 virus /

Table of Contents: “…Contents: Mortality rates of SARS-CoV-2 and known risk factors -- Provenance of SARS-CoV-2 and related viruses -- SARS-CoV-2 as compared with seasonal influenza -- Potential impact of future mutations -- Prospective therapies.…”
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Successes and failures with vaccines

Table of Contents: “…Contents: New strategies for vaccine development -- Influenza vaccines need improvement -- The microbiome influences rotavirus vaccine efficacy -- Vaccines against cytomegalovirus -- Vaccines against human papillomavirus and cervical cancer -- Insights from structural biology and the development of vaccines against respiratory syncytial virus -- Vaccines based on DNA and RNA.…”
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State of the wild, 2008-2009 : a global portrait of wildlife, wildlands, and oceans /

Table of Contents: “…Kock -- An ounce of prevention : lessons from the first avian influenza scare / William B. Karesh and Kristine Smith -- Why wildlife health matters in North America / John R. …”
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Controlling disease outbreaks the changing role of hospitals / by Nap, Raoul E.

Table of Contents: “…Preparing the health care system -- Impact of avian influenza in the Netherlands -- Hospital capacity -- Intensive care unit capacity -- Workforce -- General practitioners -- Age distribution -- Underlying disease and co-morbidity -- Mitigation of pandemic influenza -- Containment measures for pandemic influenza -- Healthcare system readiness -- Internal preparation -- Business continuity -- External preparation -- Evidence-based management -- Evidence from focused modeling : a case study from the Netherlands -- Healthcare system readiness -- Hospital and intensive care unit capacity -- Workforce -- General practitioners -- Age distribution -- Underlying disease and co-morbidity -- Mitigation and containment measures for pandemic influenza -- Methodological considerations.…”
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Innate recognition of viruses

Table of Contents: “…Contents: Induction of the adaptive Immunity -- Pattern recognition receptors: coupling innate to adaptive immunity -- Induction of type I IFNs: an example of recognition of viral patterns -- Cytosolic pathway for influenza virus recognition and inhibition by the viral -- NSI protein -- RIG-I-mediated recognition of influenza virus genomes and 5'-PPP-RNA -- Cytosolic 5'-PPP-RNA as a PAMP -- Plasmacytoid DC and the discovery of a second pathway for innate recognition of influenza virus -- Endosomal pathways for virus recognition: TLR7, TLR9 -- TLR3 as a sensor of virally-infected cells.…”
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Haemophilus

Table of Contents: “…Contents: Hemophilus influenzae -- Virulence determinants -- Immunization strategies -- Hib -- Other serotypes -- Basic structure of the H. influenzae LOS -- Sialic acids and virulence -- Phosphorylcholine (PCho) and virulence -- Phase variable genes -- Iron utilization systems -- Resistance to effectors of innate immunity -- Adhesins -- Other Haemophilus species associated with human health and disease -- Haemophilus ducreyi…”
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Antivirals versus vaccines

Table of Contents: “…Contents: Emerging infections in the past decades -- Human respiratory viruses -- The AIDS pandemic -- HIV vaccine approaches -- Antivirals use against HIV -- Morbilliviruses -- Metapneumovirus -- hMPV -- SARS-CoV -- Candidate SARS vaccines -- Vaccination of macaques against SARS -- Henipahvirus -- Smallpox -- History of smallpox vaccination -- Antiviral drugs against smallpox -- Cidofovir -- Human influenza: three appearances -- Avian influenza A virus: adaptation -- H1N1 virus: relevant mutations -- The Mexican flu virus -- Pre-pandemic H5N1 clinical trials -- The importance of an adjuvant -- Seasonal vaccine and pandemic A/H1N1 -- Flu drugs targets.…”
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Galdos and medicine / by Stannard, Michael W., 1942-

Table of Contents: “…Doctors and medicine in Galdos's madrid -- Epidemics: cholera, influenza and smallpox -- Endemic diseases: tuberculosis, syphilis, angina -- Alcoholism -- Madness -- Eye disease and blindness -- Childhood diseases -- Conclusions.…”
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Advances in disease epidemiology

Table of Contents: “…An avian influenza model and its fit to human avian influenza cases / Joseph Lucchetti, Manojit Roy and Maia Martcheva -- Gender differences in heterosexual transmission of HIV in urban and rural populations / Bernhard P. …”
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The past, present and future of vaccination

Table of Contents: “…Contents: History of vaccines, with four lessons of vaccinology -- New vaccines, including those against rotavirus, influenza, zoster and human papillomaviruses -- New strategies of vaccine development, including recombinants, vectors, plasmid DNA and non-parenteral routes of administration.…”
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Adverse effects of vaccines evidence and causality /

Table of Contents: “…Approach -- Evaluating biological mechanisms of adverse events -- Measles, mumps, and rubella vaccine -- Varicella virus vaccine -- Influenza vaccine -- Hepatitis A vaccine -- Hepatitis B vaccine -- Human papillomavirus vaccine -- Diphtheria toxoid-, tetanus toxoid-, and acellular pertussis-containing vaccines -- Meningococcal vaccine -- Injection-related adverse events -- Concluding comments.…”
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Opposition to vaccination a transatlantic discussion /

Table of Contents: “…Contents: Anti-vaccination movements in the US and the EU -- The impact of vaccine opposition on the numbers of measles and influenza cases -- The influence of public and social media on pro/anti-vaccines debate -- Lack of public trust in the pharmaceutical industry and regulatory agencies in the US and the EU -- The demographics of anti-vaccinators in the US and the UK -- Challenges in communicating the safety and importance of vaccine to the public.…”
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Plasmid biopharmaceuticals basics, applications, and manufacturing / by Prazeres, Duarte Miguel F.

Table of Contents: “…Historical perspective -- Gene transfer with plasmid biopharmaceuticals -- Product and process development -- Structure -- Analytical characterization -- Delivery -- Ethical and safety issues -- Human and veterinary markets -- Human case studies : pandemic influenza and critical limb ischaemia -- Veterinary case studies : West Nile, infectious hematopoietic necrosis, and melanoma -- GMPS and validation -- Product specifications and quality control -- Cell culture -- An overview of downstream processing -- Primary isolation -- Intermediate recovery -- Final purification -- Process synthesis -- Concluding remarks and outlook.…”
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Immunologic adjuvant research

Table of Contents: “…Adjuvants in cancer vaccinations / Ralf Kircheis, Andreas Nechansky -- TLR agonists as immune adjuvants / Yanal Murad, Bara Sarraj -- Modulating immune response with CpG-oligodeoxynucleotide through the skin / Joe Inoue, Yukihiko Aramaki -- Immunopotentiating reconstituted influenza virosomes as safe and potent antigen-delivery system for synthetic peptides in vaccines development / Claudia A. …”
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Pathology new research /

Table of Contents: “….] -- Pathological examination of influenza virus-associated and autoimmune encephalitis/encephalopathy in children / Masaharu Hayashi ... …”
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Glycoprotein maturation and quality control in the endoplasmic reticulum

Table of Contents: “…Contents: Protein maturation in the secretory pathway -- ER glycoforms -- The glyco-code of the ER -- Calnexin and calreticulin -- Cotranslational folding -- Influenza hemagglutinin -- Oxidation of HA -- HA truncations -- Type I membrane proteins -- Disease states involving ER folding and quality control -- Structural determinants that cause retention -- ER retention signals -- Calnexin binding cycle -- GT or UDP glucose glycoprotein: glycosyltransferase -- Degradation of misfolded proteins -- Carbohydrate trimming -- EDEM1 functions.…”
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Building healthy communities through medical-religious partnerships by Bennett, Richard G. (Richard Gordon)

Table of Contents: “…Healing body, mind, and soul -- Addressing challenges through medical-religious partnerships -- Congregational health education programs -- Coronary heart disease -- Hypertension -- Cancer -- Diabetes mellitus -- Depression -- Dementia -- Influenza and pneumonia -- Advance directives -- Communicating with health care providers -- Modifying common risk factors -- Managing medications -- Accidents and falls -- Community resources -- Innovative medical-religious partnerships -- National organization and resources.…”
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Structure-based drug design targeting infectious disease

Table of Contents: “…Contents: Many antibiotics inhibit the ribosome -- Intelligent engine builds perpetual pipeline -- Crystallography shows 50S is a target-of-targets -- From new X-ray crystals to new leads -- Analog(Trade Mark) -- LINKER essentials: tethering two binding features -- BOMB essentials -- MUSIC essentials: core-swapping -- QikProp: calculating drug-like properties -- Structures + Analog(Trade Mark): balanced compounds -- Case study: enhanced oxazolidinones -- Structural foundations -- Path to enhanced oxazolidinones -- Pi contributions represent key interactions -- Probing selectivity of sparsomycin -- Seeking a new lead -- Difference density map showing rib-X prototype -- Perfect match -- A minimal scaffold for lead optimization -- Minimal scaffold binds effectively in A-site -- Activity against H. influenzae -- H. influenzae activity with time evolution -- H. flu model delivers differentiable oxazolidinones -- Moderate in vivo activity measured -- Predictive model for rat oral bioavailability -- First pool of drug candidates -- Structures + predictive models = time-saving filters.…”
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