Search Results - "epigenetics"

Drug metabolism in liver disease

Table of Contents: “…Contents: Drug metabolism -- Liver disease and drug clearance -- Mechanistic explanations -- Intact hepatocyte hypothesis -- Sequential progressive model of liver disease -- Liver disease etiology -- Liver disease severity -- Epigenetics -- Biomarkers.…”
Get full text
Series

Patient specific stem cells /

Table of Contents: Click here to view.

Biology of Domestic Animals / by Scanes, Colin G.

Table of Contents: Click here to view.

Biomolecular therapeutics for human cancer

Table of Contents: “…(Publisher-supplied data) Section I: Epigenetics and Cell Cycle -- Epigenetic modulation of Cell Cycle: an overview? …”
An electronic book accessible through the World Wide Web; click to view

Genome-wide organization of chromatin and the transcription machinery

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
Get full text
Series

Genomic insights into gene regulation by cohesin

Table of Contents: “…Contents: Cohesin regulates gene expression and development in Drosophila and Humans -- Cohesin binds a subset of active genes at transcription start sites -- Cohesin directly regulates many genes Important for growth and development -- Cohesin cooperates with polycomb epigenetic silencing complexes to restrain gene expression -- Cohesin selectively binds genes with paused RNA Polymerase and regulates transition to transcriptional elongation -- Questions regarding the roles of cohesin in gene regulation and development and relevance to human disease.…”
Get full text
Series

Maintaining the silenced state of master regulatory genes during development

Table of Contents: “…-- PRC1 in compaction and ubiquitylation -- Nucleosome dynamics -- Characteristics of the compaction domain -- Gene silencing by chromatin compaction -- The SIR complex and mating type silencing -- Structural rearrangements in NCP and BAH -- Folding events in Sir3 BAH/NCP complex -- The nucleosome as a silencing machinery -- Epigenetic memory.…”
Get full text
Series

Role of polycomb proteins in gene transcription, stem cell and human diseases

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
Get full text
Series

The basal transcription machinery for RNA polymerase II

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
Get full text
Series

Enhancer malfunction in cancer

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
Get full text
Series

Hox gene regulation in vertebrate hindbrain development

“…Biomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer.…”
Get full text
Series

A historical perspective on ideas on X-chromosome inactivation

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
Get full text
Series

Genomic imprinting history and embryology /

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
Get full text
Series

Genomic imprinting and its regulation

Table of Contents: “…Contents: Introduction to imprinting -- classic embryological and genetic studies -- identification and function of imprinted genes -- imprinted domains and the organisation of imprinted clusters -- epigenetic modifications and genome programming -- cis-acting control at imprinted domains -- DNA methylation and non-coding RNA -- histone modifications -- clinical implications.…”
Get full text
Series

DNA methylation and genome defense in Neurospora crassa

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
Get full text
Series

DNA methylation

Table of Contents: “…Contents: DNA methylation as an epigenetic mark -- location and patterns of methylated and nonmethylated CpG sites in the vertebrate genome -- factors determining DNA methylation patterns -- association of DNA methylation with stable gene silencing, e.g. methylation of CpG islands on the inactive X-chromosome, ensures long term repression of associated genes -- recruitment of corepressors that impose a silent chromatin structure -- repulsion of transcriptional activators by methyl-CpG leading to gene silencing -- the link between human disorders, including cancer, Rett Syndrome and ICF syndrome, and defects in the DNA methylation system.…”
Get full text
Series

Gene silencing in budding yeast

Table of Contents: “…Contents: Gene silencing: an epigenetic phenomenon -- Chromatin remodeling: heterochromatin and euchromatin -- Silent chromatin in budding yeast: mating-type loci -- Silent information regulation: telomeric genes and Sir proteins.…”
Get full text
Series

Germ cells

Table of Contents: “…Contents: The germ cell cycle and the key epigenetic programming events in the germ cell lineage -- the oocyte and its properties -- epigenetic mechanism of germ cell specification in mice -- repression of the somatic programme, a key event during specification of germ cells -- epigenetic programming following specification of germ cells -- the relationship between germ cells and pluripotent stem cells.…”
Get full text
Series

Stem cell memory

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
Get full text
Series

X chromosome inactivation in human cells

“…Biomedical & life sciences collection. Epigenetics : concepts, theories, paradigms and mechanisms.…”
Get full text
Series