Search Results - "drug discovery"

Chiral drugs chemistry and biological action /

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Chiral drugs chemistry and biological action /

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Drug efficacy, safety, and biologics discovery emerging technologies and tools /

Table of Contents: “….] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. …”
An electronic book accessible through the World Wide Web; click to view

Drug efficacy, safety, and biologics discovery emerging technologies and tools /

Table of Contents: “….] -- Telemetry technology for preclinical drug discovery and development / Yi Yang --Nanotechnology to improve oral drug delivery / Mayank D. …”
An electronic book accessible through the World Wide Web; click to view

Biomarker Research

Open Access

Biomarker Research

Open Access

Biopharmaceutics modeling and simulations theory, practice, methods, and applications / by Sugano, Kiyohiko

Table of Contents: “…Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.…”
An electronic book accessible through the World Wide Web; click to view

Biopharmaceutics modeling and simulations theory, practice, methods, and applications / by Sugano, Kiyohiko

Table of Contents: “…Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.…”
An electronic book accessible through the World Wide Web; click to view

Integrated cardiac safety assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / by Turner, J. Rick

Table of Contents: “…The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety.…”
An electronic book accessible through the World Wide Web; click to view

Integrated cardiac safety assessment methodologies for noncardiac drugs in discovery, development, and postmarketing surveillance / by Turner, J. Rick

Table of Contents: “…The importance of cardiac safety assessments -- The biological basis of adverse drug reactions -- Cardiac structure and function -- Cardiac pathophysiology and disease -- Drug discovery and drug design -- Nonclinical development -- The thorough QT/QTc trial -- General safety assessments -- Therapeutic use trials and meta-analyses -- Assessment methodologies in nonexperimental postmarketing surveillance -- Postmarketing proarrhythmic cardiac safety assessments -- Generalized cardiac safety -- Medication errors, adherence, and concordance -- Future directions in drug safety.…”
An electronic book accessible through the World Wide Web; click to view

Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry / by Peters, Sheila Annie

Table of Contents: “…Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.…”
An electronic book accessible through the World Wide Web; click to view

Physiologically-based pharmacokinetic (PBPK) modeling and simulations principles, methods, and applications in the pharmaceutical industry / by Peters, Sheila Annie

Table of Contents: “…Modelling in the pharmaceutical industry -- Physiologically-based modelling -- A review of pharmacokinetic principles -- Physiological model for absorption -- Physiological model for distribution -- Physiological models for drug metabolism and excretion -- Generic whole-body physiologically-based pharmacokinetic modelling -- Variability, uncertainty and sensitivity analysis -- Evaluation of drug-drug interaction risk with pbpk models -- PBPK of biotherapeutics -- Data integration and sensitivity analysis -- Hypothesis generation and pharmacokinetic predictions -- Integration of PBPK and pharmacodynamics -- PBPK modelling of populations -- PBPK models along the drug discovery and development value chain.…”
An electronic book accessible through the World Wide Web; click to view

Biomedical chromatography

Table of Contents: “…Bioanalysis in drug discovery and development : focus on pharmacokinetic studies / Gilberto Alves, Ana Fortuna, Amílcar Falcão -- Characterization of drug-plasmatic protein interactions by microseparation techniques / Maria Amparo Martínez-Gómez ... …”
An electronic book accessible through the World Wide Web; click to view

Characterizing and communicating uncertainty in the assessment of benefits and risks of pharmaceutical products : workshop summary / by Caruso, Denise, English, Rebecca A., Claiborne, Anne B.

An electronic book accessible through the World Wide Web; click to view

Biomedical chromatography

Table of Contents: “…Bioanalysis in drug discovery and development : focus on pharmacokinetic studies / Gilberto Alves, Ana Fortuna, Amílcar Falcão -- Characterization of drug-plasmatic protein interactions by microseparation techniques / Maria Amparo Martínez-Gómez ... …”
An electronic book accessible through the World Wide Web; click to view

Characterizing and communicating uncertainty in the assessment of benefits and risks of pharmaceutical products : workshop summary / by Caruso, Denise, English, Rebecca A., Claiborne, Anne B.

An electronic book accessible through the World Wide Web; click to view

Cell & Bioscience

Open Access

Cell & Bioscience

Open Access

Enzyme technologies metagenomics, evolution, biocatalysis, and biosynthesis /

An electronic book accessible through the World Wide Web; click to view

Enzyme technologies metagenomics, evolution, biocatalysis, and biosynthesis /

An electronic book accessible through the World Wide Web; click to view