Search Results - "chromatin"

Histone dynamics, heritability and variants

Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
Get full text
Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

Histone dynamics, heritability and variants

Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
Get full text
Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

Polycomb epigenetic mechanisms part 1 of 2, role of PcG complexes /

Subjects: “…Chromatin.…”
Get full text
Series

Role of polycomb proteins in gene transcription, stem cell and human diseases

Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
Get full text
Series

Gene silencing in budding yeast

Table of Contents: “…Contents: Gene silencing: an epigenetic phenomenon -- Chromatin remodeling: heterochromatin and euchromatin -- Silent chromatin in budding yeast: mating-type loci -- Silent information regulation: telomeric genes and Sir proteins.…”
Get full text
Series

The molecular mechanism of X chromosome inactivation

Table of Contents: “…Contents: X chromosome inactivation -- The X inactivation centre (Xic) -- Key role of the Xist locus -- Towards an understanding of Xist gene regulation in early mouse development -- Mechanisms regulating Xist RNA localisation within the inactive X chromosome territory -- Chromatin modification and gene silencing by Xist RNA.…”
Get full text
Series

Gene silencing in budding yeast

Table of Contents: “…Contents: Gene silencing: an epigenetic phenomenon -- Chromatin remodeling: heterochromatin and euchromatin -- Silent chromatin in budding yeast: mating-type loci -- Silent information regulation: telomeric genes and Sir proteins.…”
Get full text
Series

The molecular mechanism of X chromosome inactivation

Table of Contents: “…Contents: X chromosome inactivation -- The X inactivation centre (Xic) -- Key role of the Xist locus -- Towards an understanding of Xist gene regulation in early mouse development -- Mechanisms regulating Xist RNA localisation within the inactive X chromosome territory -- Chromatin modification and gene silencing by Xist RNA.…”
Get full text
Series

Enhancer malfunction in cancer

Table of Contents: “…Contents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? …”
Get full text
Series

Enhancer malfunction in cancer

Table of Contents: “…Contents: MLL genes and their pathogenic translocations -- Yeast, mammalian and Drosophila systems for studying leukaemia pathogenesis -- Proteins and protein complexes that regulate chromatin modifications, transcription initiation, and transcription elongation -- What is the function of MLL? …”
Get full text
Series

Epigenetic control by histone methylation

Table of Contents: “…Contents: The diversity of covalent histone tail modifications for imparting epigenetic information -- Observations of robust histone modifications at silent chromatin regions -- The representation of repressive histone marks as indications of epigenetic plasticity in different cells -- Analysis of the profiles of normal and aberrant histone lysine methylation patterns, as they occur during the transition of an embryonic to a differentiated cell or in controlled self-renewal vs. pro-neoplastic or metastatic conditions -- Elucidation of these histone modification patterns for novel advances in stem cell research, nuclear reprogramming and cancer.…”
Get full text
Series

Polycomb epigenetic mechanisms part 1 of 2, role of PcG complexes /

Subjects: “…Chromatin. 94771…”
Get full text
Series

Role of polycomb proteins in gene transcription, stem cell and human diseases

Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
Get full text
Series

Polycomb epigenetic mechanisms part 1 of 2, role of PcG complexes /

Subjects: “…Chromatin. 94771…”
Get full text
Series

Role of polycomb proteins in gene transcription, stem cell and human diseases

Table of Contents: “…Contents: Chromatin structure -- Histone modification and regulation of methylation -- Polycomb complexes (gene silencing, recruitement & displacement of proteins, protein levels in embryoid bodies, binding regulation) -- PcG genes and human cancers -- Variations of Polycomb Repressive Complexes and their associations with polycomb proteins -- CBX family of proteins -- The Polycomb-like gene family.…”
Get full text
Series

Activation of gene expression by double-stranded RNAs

Subjects: Get full text
Series

DNA methylation

Subjects: Get full text
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

Accessing and using ENCODE data

Table of Contents: “…Contents: A description of the ENCODE Consortium -- Experimental assays used by Consortium members -- Overview of genome-wide methods to study gene expression, chromatin, and transcription factors -- A summary of insights from ENCODE experiments -- How to access and download ENCODE data -- How to use ENCODE data in your own research.…”
Get full text
Series (Eukaryotic gene regulation)
Series (Introduction to human genetics)
Series (Using bioinformatics in the exploration of genetic diversity)
Series (Epigenetics, chromatin, transcription and cancer)

Legacy of Drosophila genetics female germline stem cells /

Table of Contents: “…Contents: Lineage tracing -- Stem cell niches -- Germline stem cell niche in ovary -- Germline stem cell niche in testis – Dedifferentiation -- Stem cell signaling back to the niche -- Intestinal stem cells -- Stem cell chromatin.…”
Get full text
Series

Cancer-specific epigenetic alterations as investigated from a pharmaceutical perspective

Table of Contents: “…Contents: Chromatin dysregulation in cancer -- Features of epigenetic information in cells -- Mutated chromatin regulatory factors as tumor drivers -- Therapeutic rationale for the use of epigenetic drugs in oncology -- First generation epigenetic drugs: DNMT and HDAC inhibitors -- Novel therapeutic discoveries in oncology -- Biomarkers for patient selection.…”
Get full text