Search Results - "amyloid"
Suggested Topics within your search.
Suggested Topics within your search.
- Amyloid 74
- Alzheimer Disease 53
- Prions 48
- Alzheimer's disease 39
- metabolism 21
- Neurodegenerative Diseases 20
- Protein Folding 18
- pathology 18
- physiopathology 18
- Nervous system 17
- Degeneration 16
- Proteins 16
- Protein Conformation 15
- drug therapy 15
- Genetic aspects 14
- genetics 14
- Amyloid beta-Peptides 13
- Chemotherapy 13
- Treatment 12
- therapy 11
- Amyloid beta-protein 9
- Pathophysiology 9
- Protein folding 9
- Brain 8
- Dementia 8
- Diagnosis 8
- Pathology 8
- Frontotemporal Dementia 7
- Amyloidosis 6
- Diagnostic Imaging 6
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81
Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /
Published 2014Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
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82
Update on fluid biomarkers for neurodegenerative diseases
Published 2022Table of Contents: “…Contents: Fluid biomarker candidates for neurodegenerative disease -- Amyloid pathology -- CSF and plasma/serum NfL -- CSF Aβ42 in Alzheimer's disease and neuroinflammatory diseases -- Tau pathology in Alzheimer's disease -- Neurodegeneration -- CSF and plasma NfL as biomarkers for disease progression -- Drug treatment and NfL levels.…”
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Series (Biomarkers)
Series (Drug discovery and development in the neurosciences)
Series (Genetic basis of neurological disorders)
Electronic Video -
83
Update on fluid biomarkers for neurodegenerative diseases
Published 2022Table of Contents: “…Contents: Fluid biomarker candidates for neurodegenerative disease -- Amyloid pathology -- CSF and plasma/serum NfL -- CSF Aβ42 in Alzheimer's disease and neuroinflammatory diseases -- Tau pathology in Alzheimer's disease -- Neurodegeneration -- CSF and plasma NfL as biomarkers for disease progression -- Drug treatment and NfL levels.…”
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Series (Biomarkers)
Series (Drug discovery and development in the neurosciences)
Series (Genetic basis of neurological disorders)
Electronic Video -
84
The blood-brain barrier in Alzheimer's disease
Published 2021Subjects: Get full text
Series
Electronic Video -
85
Frontotemporal dementia
Published 2010Table of Contents: “…Contents: Prevalence and nomenclature of FTD -- The pathology of FTD (tau, TDP-43) -- The genetics of FTD (tau, progranulin) -- Patterns of atrophy and neuroanatomical correlates of behavior and cognition -- von Economo neurons -- Neuroimaging (amyloid imaging) -- Treatment.…”
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86
Frontotemporal dementia
Published 2010Table of Contents: “…Contents: Prevalence and nomenclature of FTD -- The pathology of FTD (tau, TDP-43) -- The genetics of FTD (tau, progranulin) -- Patterns of atrophy and neuroanatomical correlates of behavior and cognition -- von Economo neurons -- Neuroimaging (amyloid imaging) -- Treatment.…”
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Series
Electronic Video -
87
The blood-brain barrier in Alzheimer's disease
Published 2021Subjects: Get full text
Series
Electronic Video -
88
Genetics of early onset Alzheimer's disease
Published 2014Table of Contents: “…Contents: Role of amyloid precursor protein (APP) in Alzheimer's Disease (AD) -- Presenilins as AD causing genes -- Phenotypic heterogeneity in cases with presenilin mutations -- Gene-gene interactions in patients with AD -- Genetic testing in AD.…”
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Series
Electronic Video -
89
A molecular understanding of Alzheimer's disease
Published 2021Table of Contents: “…Contents: Usefulness of genetics in understanding AD -- Pathology of diseases -- Amyloid protein -- Genetic maps -- Mechanism of late onset Alzheimer's -- Role of presenilin in amyloid pathology -- Tau and frontotemporal dementia -- Tau splice site mutations -- Pathways to neurodegeneration.…”
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Series
Electronic Video -
90
A molecular understanding of Alzheimer's disease
Published 2021Table of Contents: “…Contents: Usefulness of genetics in understanding AD -- Pathology of diseases -- Amyloid protein -- Genetic maps -- Mechanism of late onset Alzheimer's -- Role of presenilin in amyloid pathology -- Tau and frontotemporal dementia -- Tau splice site mutations -- Pathways to neurodegeneration.…”
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Series
Electronic Video -
91
Chaperones and prions
Published 2020Table of Contents: “…Contents: Prion diseases -- Prions as self-propagating amyloids -- Yeast prions as protein-based heritable elements -- Prion detection -- Crucial role of the chaperone protein Hsp104 in the propagation of yeast prions -- Chaperone-mediated fragmentation turns amyloids into infectious or heritable prions -- Effects of the Hsp70 and Hsp40 proteins on yeast prions -- Other modulators of prion formation and propagation: cytoskeleton and ubiquitin system.…”
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92
Chaperones and prions
Published 2020Table of Contents: “…Contents: Prion diseases -- Prions as self-propagating amyloids -- Yeast prions as protein-based heritable elements -- Prion detection -- Crucial role of the chaperone protein Hsp104 in the propagation of yeast prions -- Chaperone-mediated fragmentation turns amyloids into infectious or heritable prions -- Effects of the Hsp70 and Hsp40 proteins on yeast prions -- Other modulators of prion formation and propagation: cytoskeleton and ubiquitin system.…”
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Series
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93
Humoral innate immunity and the acute phase response 2
Published 2016Subjects: Get full text
Series (Innate immunity)
Series (Cytokines)
Electronic Video -
94
Genetics of early onset Alzheimer's disease
Published 2014Table of Contents: “…Contents: Role of amyloid precursor protein (APP) in Alzheimer's Disease (AD) -- Presenilins as AD causing genes -- Phenotypic heterogeneity in cases with presenilin mutations -- Gene-gene interactions in patients with AD -- Genetic testing in AD.…”
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Series
Electronic Video -
95
Genetics of early onset Alzheimer's disease
Published 2014Table of Contents: “…Contents: Role of amyloid precursor protein (APP) in Alzheimer's Disease (AD) -- Presenilins as AD causing genes -- Phenotypic heterogeneity in cases with presenilin mutations -- Gene-gene interactions in patients with AD -- Genetic testing in AD.…”
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Series
Electronic Video -
96
Neurodegenerative disease expression levels of normal sequence pathogenic proteins contribute to risk of disease /
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97
Neurodegenerative disease expression levels of normal sequence pathogenic proteins contribute to risk of disease /
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Series
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98
Humoral innate immunity and the acute phase response 2
Published 2016Subjects: Get full text
Series (Innate immunity)
Series (Cytokines)
Electronic Video -
99
Humoral innate immunity and the acute phase response 2
Published 2016Subjects: Get full text
Series (Innate immunity)
Series (Cytokines)
Electronic Video -
100
Mechanism of prion generation in vitro
Published 2020“…Biomedical & life sciences collection. Prions and amyloids : self-propagating protein structures in mammals, yeast and fungi.…”
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Electronic Video