Search Results - "RNA splicing"

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    Biased signaling at mu opioid receptor splice variants

    Published 2020
    Table of Contents: “…Contents: Extensive alternative pre-mRNA splicing of the mu opioid receptor gene (OPRM1) -- Distinct intracellular C-terminal tails in different full-length 7TM C-terminal variants -- Distinct in vivo functions of several C-terminal tails -- In vivo truncation of C-terminal tails encoded by E7 affects morphine tolerance and reward -- In vivo truncation of C-terminal tails encoded by E4 affects morphine tolerance and dependence.…”
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    Electronic Video