Search Results - "RNA interference"
Suggested Topics within your search.
Suggested Topics within your search.
- RNA Interference 25
- RNA, Small Interfering 11
- Small interfering RNA 8
- therapeutic use 5
- MicroRNAs 4
- Therapeutic use 4
- genetics 4
- therapy 4
- Gene therapy 3
- Genetic Therapy 3
- RNA 3
- Ribonuclease III 3
- metabolism 3
- Antiviral agents 2
- Argonaute Proteins 2
- Cancer 2
- Drug development 2
- Gene Silencing 2
- Gene Targeting 2
- Gene Transfer Techniques 2
- Gene silencing 2
- Genetic aspects 2
- Genetic regulation 2
- Genetic vectors 2
- HIV Infections 2
- HIV infections 2
- MicroRNA 2
- Molecular Targeted Therapy 2
- Molecular aspects 2
- Neoplasms 2
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RNA interference
Published 2008An electronic book accessible through the World Wide Web; click to view
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RNA interference and cancer a revolution? /
Published 2007Table of Contents: “…Contents: Cancer overview -- RNA interference to understand cancer -- Natural short RNAs in cancer -- RNA interference to fight cancer.…”
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RNA interference for neurodegenerative diseases
Published 2007Table of Contents: “…Contents: Brain diseases and molecular therapies -- RNA interference -- Mice models of brain disease -- Viral vectors.…”
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RNAi specificity how big of an issue is it? /
Published 2007Subjects: “…RNA Interference. 110074…”
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MicroRNA biogenesis
Published 2007Subjects: “…RNA Interference. 110206…”
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Cell signalling pathways and RNAi
Published 2007Subjects: “…RNA Interference. 110209…”
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Therapeutic delivery of RNAi
Published 2007Subjects: “…RNA Interference. 110251…”
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RNAi in the model system Drosophila
Published 2007Subjects: “…RNA Interference. 110344…”
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Mechanisms of RNAi a molecular view or Argonaute : the secret life of slicer /
Published 2007Subjects: “…RNA Interference. 110412…”
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Specific functional roles in mammals
Published 2007Table of Contents: “…-- Harnessing the RNA interference pathway for genetic analysis -- Genetic ablation of the catalytic engine for small RNA production in the mouse.…”
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Activation of gene expression by double-stranded RNA
Published 2010Subjects: “…RNA Interference. 113808…”
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RNA interference functions and mechanisms in animals
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Systemic RNA interference (RNAi) therapeutics for the treatment of HIV-1
Published 2014Table of Contents: “…Contents: Systemic RNA interference (RNAi): Therapeutics for the treatment of HIV-1 -- HIV life cycle -- Typical Course of HIV infection -- Why do we need new HIV drugs? …”
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New designs for siRNAs as Dicer-substrates
Published 2007Subjects: “…RNA Interference. 109848…”
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Functional roles of RNAi in C. elegans
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RNAi and heterochromatin in plants and fission yeast
Published 2007Table of Contents: “…Contents: Heterochromatin is composed of transposable elements (TEs) and related repeats -- heterochromatic gene silencing and TE-mediated silencing are related and may be important in large genomes -- tiling microarrays can be used to examine heterochromatic transcripts as well as DNA and histone modification -- small interfering RNA (siRNA) corresponds to transposons and repeats -- in plants TE siRNA depend on DNA methyltransferase MET1 and the SWI/SNF ATPase DDM1 which silence TEs via DNA and histone H3 lysine-9 (H3K9) methylation -- in fission yeast and plants centromeric repeats are transcribed on one strand but rapidly turned over by RNA interference (RNAi) -- RNAi of centromeric transcripts is required for transcriptional silencing of reporter genes -- RNA polymerase II, the Argonaute (RITS) and RNA dependent RNA polymerase (RDRC) complexes are associated with heterochromatin and required for silencing -- H3K9me2 depends on RNAi and on the Rik1-Clr4 complex -- Clr4 is the histone H3K9 dimethyltransferase -- Rik1 resembles both DNA and RNA binding proteins and is required for RNAi along with Clr4 -- LTR retrotransposon silencing depends on histone deacetylation and silences pericentromeric repeats in Arabidopsis in addition to RNAi.…”
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Small interfering RNA induced transcriptional gene silencing in human cells
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Mammalian microRNP assembly & function
Published 2007Table of Contents: “…Contents: miRNAs and RNA interference, nuclear biogenesis and cytoplasmic processing -- siRNA biogenesis and assembly -- Silencing by target mRNA cleavage and "translational repression" -- RISC assembly in flies -- RISC activity and Dicer -- Model of the miRNA assembly pathway in humans -- Prediction of miRNA targets -- Compensatory mutations: rescue -- How miRNAs and siRNAs recognize their targets -- Additional principles of target RNA recognition by miRNAs and siRNAs.…”
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