Search Results - "Pharmacology"

Laboratory methods for the in vitro study of drug metabolism

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Polymeric gels for drug delivery

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Introduction to drug metabolism enzymes

Subjects: “…Enzymes and Coenzymes pharmacology. 97670…”
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Environmental toxicity of nanomaterials /

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Inhibiting protein-protein interactions part 2 of 2 /

Subjects: “…Small Molecule Libraries pharmacology. 104240…”
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Patient stratification for drug treatment in oncology and other diseases

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Imatinib as a paradigm of targeted cancer therapies

Subjects: “…Antineoplastic Agents pharmacology. 110127…”
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Series (Signal transduction via protein tyrosine kinase receptors)
Series (Small molecule drug discovery)

Animal models of seizures and epilepsy

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Series (Animal models in biomedical research)
Series (Epilepsy and seizures)

Peptide YY (PYY) in obesity and diabetes

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Modeling of antibody-drug conjugate pharmacokinetics

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Historical and ethical issues in trial design

Table of Contents: “…Contents: Historical antecedents to the clinical trial -- Pharmacology & mathematical statistics as key for clinical trials -- Shortage of streptomycin during WWII & use of control groups -- Unethical research studies & informed consent by study subjects -- Withholding a potentially useful therapy -- Letting chance determine patient assignment -- Advancing scientific knowledge without reducing study participants to a means to an end -- General ethical frameworks of Utilitarianism & Kantianism -- Eight factors to be considered in designing ethical and scientific studies.…”
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Monoclonal antibodies to induce therapeutic immunological tolerance

Subjects: “…Antibodies, Monoclonal pharmacology. 92123…”
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Enzymology in drug discovery part 2 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
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Key considerations for cancer pharmacotherapy part 1 of 2 /

Table of Contents: “…Contents: Localized and systemic therapy options used in cancer treatment -- Chemotherapy delivery and factors influencing efficacy -- Common cancer targets and related therapies -- Basic pharmacology of targeted therapy options.…”
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Antibody engineering beginnings to bispecifics and beyond /

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Series (Periodic reports)
Series (The Immune System - key concepts and questions)
Series (Monoclonal antibodies as therapeutic agents)

Translational medicine the risk of failure in delay and how to reduce it /

Table of Contents: “…Contents: Translational medicine -- Biomarker development -- Risk assessment -- Risk estimator -- Scoring system -- Structured approach -- Clinical pharmacology -- Interdisciplinary cooperation.…”
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Enzymology in drug discovery part 1 of 2 /

Table of Contents: “…Contents: Enzymes as targets for drug discovery -- Protein-ligand binding equilibria -- Enzyme reaction mechanisms -- Structure and function of enzyme active sites -- Measuring enzyme velocity in the laboratory -- Reversible modes of enzyme inhibition -- Enzyme inhibition as a mechanism of pharmacological intervention in disease -- Clinical value of different inhibition modalities -- Non-classical inhibition -- Enzyme assays and screening criteria -- Lead optimization -- Summary: basic information to look for.…”
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Pharmacotherapy of osteoporosis part 1 of 2 /

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The role of exosomes in multiple myeloma development & drug resistance

Subjects: “…Antineoplastic Agents pharmacology. 92731…”
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Accelerating drug discovery with machine learning and AI

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