Search Results - "Genetics"

Human genetic variation of Africa

Table of Contents: “…Contents: Neutral genetic variation and African prehistory -- Non-neutral genetic variation of Africa and natural selection -- Social and medical implications of genetic variation in Africa -- Resources.…”
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Genetic diseases in the Jewish population

Table of Contents: “…Contents: Jewish history and genetics -- Classification of Jews -- Genetic diseases found in Jews, particularly Ashkenazi Jews -- Lysosomal storage diseases -- Natural selection (heterozygote advantage) vs. genetic drift -- Mutation frequencies, ages and geographic distributions -- Bottlenecks in Jewish history.…”
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Genetic conflicts in human pregnancy

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Multistage sampling for genetic studies

Table of Contents: “…Contents: Classical paradigm for rare monogenic diseases -- Multistage designs for association studies, common complex diseases -- Random and multiplex family samples, case-control samples -- Genetic epidemiology: segregation analysis, linkage analysis, association analysis -- Sampling to minimize cost -- Multiphase analysis to increase power, multiple comparisons.…”
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The genetic architecture of complex traits lessons from Drosophila /

Table of Contents: “…Contents: Complex traits -- Identifying multiple genes and environmental risk factors -- Nature of genetic variation affecting complex traits -- Drosophila as a model system -- P-element mutagenesis -- Whole genome transcript profiles of genetically divergent strains -- QTL mapping -- Association mapping -- Large numbers of loci -- Pleiotropic effects on multiple traits -- Sex, environment and genetic background dependent effects.…”
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Genetic testing for CHD risk fact or fiction? /

Table of Contents: “…Contents: Family history is a strong independent risk factor for early CHD -- Criteria for useful CHD-Risk DNA tests -- Analytical validity -- Clinical validity -- Risk estimates for genetic effects -- Clinical utility -- Risk score methods -- CRP: origin, clearance and function -- Is it likely that genotype will predict risk over and above trait measure? …”
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Human genetics of infectious diseases the example of bacterial / mycobacterial infections /

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Genetic association analysis with R

Table of Contents: “…Contents: R environment for statistical analysis -- Rationale of R for genetic data -- Use of packages -- Haplotype analysis -- Regional association -- The Framingham data -- GenABEL -- Q-Q and Manhattan plots -- GWAS -- Issues and challenges -- Meta-analysis -- Use of publically available data -- A technical summary.…”
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Thirty years of Azheimer's genetics what's new and what's next? /

Subjects: “…Alzheimer Disease genetics. 109131…”
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Genetic influences on human epilepsy

Table of Contents: “…Contents: Genetic techniques used to identify epilepsy genes -- Seizures in mice -- Translating mice genes to human genes -- Identified epileptic genes -- Neural transmission genes -- Ion flux genes -- Neuro-development genes.…”
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The genetic structure of Mycobacterium tuberculosis insights into genome organisation and evolution of the causative agent of tuberculosis /

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Genetic basis of neurological disease

Table of Contents: “…Contents: Neurogenetics -- Allele frequency vs. effect size -- Parkinson's disease (PD) -- PINK1: genetic discovery to protein expression -- Pink1 and mitochondrial abnormalities -- In vivo interaction between PINK1 and Parkin -- Parkinsonian proteins and mitophagy -- Mitochondrial dysfunction -- Protein aggregation -- Ceramide metabolism and PD -- Lysosomal pathway and PD -- Complex trait genetics -- Linkage disequilibrium blocks -- Identifying common genetic factors -- Genetic risk factors & odds of finding variants -- First genome-wide association study for PD -- Parkinson's disease molecular pathways -- Replicate meta-analysis -- The major neurological diseases -- Caveats to consider in GWAS -- The ENCODE study -- Trinucleotide repeats and related disorders -- The impact of next generation sequencing.…”
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The genetic basis of kidney cancer

Subjects: “…Cancer Genetic aspects. 103232…”
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Series (Molecular genetics of human disease)
Series (Kidney in health and disease)

Genetic and linguistic evolution and coevolution

Table of Contents: “…-- Regional studies of language and population genetic evolution.…”
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Genetic drift in human evolution part 1 of 2 /

Table of Contents: “…Contents: Introduction to genetic drift -- Hardy-Weinberg equilibrium -- Experimental observations of genetic drift -- Wright-Fisher model -- Computational simulations.…”
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Genetic variation in North America

Table of Contents: “…Contents: Ethical & social implications of genetic research in indigenous communities -- A multidisciplinary approach to infer evolutionary history -- Genetic variation studies in Native Americans -- Ancient DNA research to bypass genomic effects of European colonization -- Non-indigenous admixture in Native Americans.…”
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Genetic variation in gene regulation

Table of Contents: “…Contents: Expression Quantitative Trait Loci: linking genetic variation to changes in gene regulation -- How do SNPs impact gene regulation -- HapMap cell lines as a model system for studying expression variation -- eQTL analysis -- dsQTL -- Histone marks -- Protein-specific QTLs.…”
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Genetic drift in human evolution part 2 of 2 /

Table of Contents: “…Contents: Genomic signature of genetic drift on human populations -- Serial founder effect model -- Genetic drift signature on the site frequency spectrum (SFS) -- Future directions.…”
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An introduction to genetic association analysis

Table of Contents: “…Contents: What is genetic association -- Testing for genetic association -- Quantitative trait analysis -- Covariates -- Family-based tests -- Multi-SNP models.…”
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Causal inference in genetic epidemiology Mendelian randomization and beyond /

Subjects: “…Genetic disorders Epidemiology. 96439…”
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