Search Results - "DNA methylation"

Introduction to epigenetics

Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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Skin epigenetics how chromatin regulators orchestrate skin functions /

Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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Epigenetics and inheritance

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Epigenetics and inheritance

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Role of polycomb proteins in gene transcription, stem cell and human diseases

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Skin epigenetics how chromatin regulators orchestrate skin functions /

Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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Skin epigenetics how chromatin regulators orchestrate skin functions /

Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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Epigenetics and Assisted Reproduction An Introductory Guide. by Camprubí, Cristina

Table of Contents: “…Cover; Half Title; Title Page; Copyright Page; Contents; Preface; Contributors; Chapter 1: A Short Introduction to DNA Methylation; Chapter 2: Epigenetic Modifications of Histones; Chapter 3: Epigenetic Reprogramming in Early Embryo Development; Chapter 4: Epigenetic Reprogramming of Mammalian Primordial Germ Cells; Chapter 5: Laboratory Molecular Methodologies to Analyze DNA Methylation; Chapter 6: Intrinsic and Extrinsic Factors That Influence Epigenetics; Chapter 7: Epigenetic and Assisted Reproduction Epidemiological Studies…”
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Genomic imprinting and its regulation

Table of Contents: “…Contents: Introduction to imprinting -- classic embryological and genetic studies -- identification and function of imprinted genes -- imprinted domains and the organisation of imprinted clusters -- epigenetic modifications and genome programming -- cis-acting control at imprinted domains -- DNA methylation and non-coding RNA -- histone modifications -- clinical implications.…”
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Genomic imprinting and its regulation

Table of Contents: “…Contents: Introduction to imprinting -- classic embryological and genetic studies -- identification and function of imprinted genes -- imprinted domains and the organisation of imprinted clusters -- epigenetic modifications and genome programming -- cis-acting control at imprinted domains -- DNA methylation and non-coding RNA -- histone modifications -- clinical implications.…”
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Genomic imprinting and its regulation

Table of Contents: “…Contents: Introduction to imprinting -- classic embryological and genetic studies -- identification and function of imprinted genes -- imprinted domains and the organisation of imprinted clusters -- epigenetic modifications and genome programming -- cis-acting control at imprinted domains -- DNA methylation and non-coding RNA -- histone modifications -- clinical implications.…”
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Asthma an epidemic caused by epigenetics? /

Table of Contents: “…Contents: Genetic and biological determinants of diseases influenced by the environment -- Epigenetics -- Epigenetic mechanisms can be influenced by environmental exposures and aging -- Histone modifications and innate immunity -- Asthma is a major public health problem -- Epigenetics and airway immunology -- DNA methylation changes and asthma -- Runx3 and airway disease -- In utero folate supplementation and asthma -- Sib pair asthma study -- preliminary analysis -- Global methylation patterns: asthmatics vs. nonasthmatics -- Hypomethylation of GATA3 or MUC5B is associated with asthma in concordant sib pairs -- Hypermethylation of NOS2 is associated with concordant asthma -- Asthma: an epidemic caused by epigenetics?…”
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Microarrays their design and use /

Table of Contents: “…Contents: The use of microarrays to study genomic DNA and expressed RNA at a global level are being developed at a phenomenal pace in the basic and medical sciences -- The basics of microarrays -- Fundamental descriptions and issues regarding experimental design, high-throughput approaches, analysis, and bioinformatics -- Different microarray platforms can be used to examine single nucleotide polymorphisms (SNP) of the genome, differential mRNA levels, differential microRNA (miRNA) levels, DNA methylation, genomic deletions and additions, DNA binding sites, and transcription rates -- Microarrays in the diagnosis, prognosis, and treatment of disease -- Microarrays in evolution, ecology and toxicology -- The future of microarray technology.…”
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Microarrays their design and use /

Table of Contents: “…Contents: The use of microarrays to study genomic DNA and expressed RNA at a global level are being developed at a phenomenal pace in the basic and medical sciences -- The basics of microarrays -- Fundamental descriptions and issues regarding experimental design, high-throughput approaches, analysis, and bioinformatics -- Different microarray platforms can be used to examine single nucleotide polymorphisms (SNP) of the genome, differential mRNA levels, differential microRNA (miRNA) levels, DNA methylation, genomic deletions and additions, DNA binding sites, and transcription rates -- Microarrays in the diagnosis, prognosis, and treatment of disease -- Microarrays in evolution, ecology and toxicology -- The future of microarray technology.…”
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Microarrays their design and use /

Table of Contents: “…Contents: The use of microarrays to study genomic DNA and expressed RNA at a global level are being developed at a phenomenal pace in the basic and medical sciences -- The basics of microarrays -- Fundamental descriptions and issues regarding experimental design, high-throughput approaches, analysis, and bioinformatics -- Different microarray platforms can be used to examine single nucleotide polymorphisms (SNP) of the genome, differential mRNA levels, differential microRNA (miRNA) levels, DNA methylation, genomic deletions and additions, DNA binding sites, and transcription rates -- Microarrays in the diagnosis, prognosis, and treatment of disease -- Microarrays in evolution, ecology and toxicology -- The future of microarray technology.…”
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Asthma an epidemic caused by epigenetics? /

Table of Contents: “…Contents: Genetic and biological determinants of diseases influenced by the environment -- Epigenetics -- Epigenetic mechanisms can be influenced by environmental exposures and aging -- Histone modifications and innate immunity -- Asthma is a major public health problem -- Epigenetics and airway immunology -- DNA methylation changes and asthma -- Runx3 and airway disease -- In utero folate supplementation and asthma -- Sib pair asthma study -- preliminary analysis -- Global methylation patterns: asthmatics vs. nonasthmatics -- Hypomethylation of GATA3 or MUC5B is associated with asthma in concordant sib pairs -- Hypermethylation of NOS2 is associated with concordant asthma -- Asthma: an epidemic caused by epigenetics?…”
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Asthma an epidemic caused by epigenetics? /

Table of Contents: “…Contents: Genetic and biological determinants of diseases influenced by the environment -- Epigenetics -- Epigenetic mechanisms can be influenced by environmental exposures and aging -- Histone modifications and innate immunity -- Asthma is a major public health problem -- Epigenetics and airway immunology -- DNA methylation changes and asthma -- Runx3 and airway disease -- In utero folate supplementation and asthma -- Sib pair asthma study -- preliminary analysis -- Global methylation patterns: asthmatics vs. nonasthmatics -- Hypomethylation of GATA3 or MUC5B is associated with asthma in concordant sib pairs -- Hypermethylation of NOS2 is associated with concordant asthma -- Asthma: an epidemic caused by epigenetics?…”
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Epigenetically mediated gene silencing a companion to genetic alterations in driving tumorigenesis /

Table of Contents: “…Contents: Introduction to epigenetic changes in cancer -- defining the process of promoter DNA hypermethylation as a constituent of a broad range of chromatin abnormalities in cancer -- defining the genes aberrantly silenced in cancer including approaches being used to screen the cancer genome for such genes -- defining what is known about the interaction of DNA methylation and chromatin modifications for initiating and maintaining gene silencing in cancer -- outlining the position of aberrant gene silencing in tumor progression and particularly highlighting the key role these changes may play for the earliest steps in tumorigenesis -- defining the potential for using DNA hypermethylated gene promoter sequences as molecular markers for cancer risk assessment, early diagnosis and prognosis -- discussing the possibilities for targeting reversal of gene silencing as a prevention and therapeutic strategy for cancer.…”
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Epigenetically mediated gene silencing a companion to genetic alterations in driving tumorigenesis /

Table of Contents: “…Contents: Introduction to epigenetic changes in cancer -- defining the process of promoter DNA hypermethylation as a constituent of a broad range of chromatin abnormalities in cancer -- defining the genes aberrantly silenced in cancer including approaches being used to screen the cancer genome for such genes -- defining what is known about the interaction of DNA methylation and chromatin modifications for initiating and maintaining gene silencing in cancer -- outlining the position of aberrant gene silencing in tumor progression and particularly highlighting the key role these changes may play for the earliest steps in tumorigenesis -- defining the potential for using DNA hypermethylated gene promoter sequences as molecular markers for cancer risk assessment, early diagnosis and prognosis -- discussing the possibilities for targeting reversal of gene silencing as a prevention and therapeutic strategy for cancer.…”
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Epigenetically mediated gene silencing a companion to genetic alterations in driving tumorigenesis /

Table of Contents: “…Contents: Introduction to epigenetic changes in cancer -- defining the process of promoter DNA hypermethylation as a constituent of a broad range of chromatin abnormalities in cancer -- defining the genes aberrantly silenced in cancer including approaches being used to screen the cancer genome for such genes -- defining what is known about the interaction of DNA methylation and chromatin modifications for initiating and maintaining gene silencing in cancer -- outlining the position of aberrant gene silencing in tumor progression and particularly highlighting the key role these changes may play for the earliest steps in tumorigenesis -- defining the potential for using DNA hypermethylated gene promoter sequences as molecular markers for cancer risk assessment, early diagnosis and prognosis -- discussing the possibilities for targeting reversal of gene silencing as a prevention and therapeutic strategy for cancer.…”
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