Search Results - "DNA"

  1. 421
  2. 422

    Congenital syndromes of pain and painlessness

    Published 2014
    Table of Contents: “…-- Pain pathways -- Types of pain (Nociceptive, Inflammatory, Neuropathic, mixed) -- Primary erythromelalgia -- Mutations in SCN9A cause erythromelalgia -- Voltage-gated ion channels -- Paroxysmal extreme pain disorder (familial rectal pain) -- Mutations in SCN9A cause PEPD -- Congenital insensitivity to pain -- SCN9A gene map -- Electrical activity of wild type versus mutant constructs -- Low-copy number vector = pcDNA3JC -- Exon 6 splice variants -- Neuropathies HSANs -- Rita Levi Montalcini -- TRKA signalling -- Hereditary autonomic and sensory neuropathy type 4 (HSAN4) -- HSAN5 -- NGFB -- Familial dysautonomia -- Treatment of pain -- Mendelian disorders of pain.…”
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  3. 423

    A short history of Ireland by Ranelagh, John

    Published 2012
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  4. 424

    Genome Editing in Neurosciences

    Published 2017
    Table of Contents: “…Introduction -- In vitro modeling of complex neurological diseases -- Aquatic model organisms in neurosciences : the genome editing revolution -- Genome-wide genetic screening in the mammalian CNS -- CRISPR/Cas9-mediated Knockin and Knockout in Zebrafish -- Dissecting the role of synaptic proteins with CRISPR -- Recurrently Breaking Genes in Neural Progenitors: Potential Roles of DNA Breaks in Neuronal Function, Degeneration and Cancer -- Neuroscience research using non-human primate models and genome editing -- Multiscale genome engineering: Genome-wide screens and targeted approaches -- Using Genome Engineering to Understand Huntington’s Disease -- Therapeutic gene editing in muscles and muscle stem cells.…”
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  5. 425

    The molecular biology of cancer

    Published 2006
    Table of Contents: “…Introduction / Stella Pelengaris, Mike Khan -- The burden of cancer / William Steward, Anne Thomas -- Nature and nurture in oncogenesis / Stella Pelengaris, Mike Khan -- DNA replication and the cell cycle / Stella Pelengaris, Mike Khan -- Regulation of growth : growth factors, receptors and signaling pathways / Stella Pelengaris, Mike Khan -- Oncogenes / Stella Pelengaris, Mike Khan -- Tumour suppressor genes / Martine Roussel -- Apoptosis / Stella Pelengaris, Mike Khan -- Telomeres and senescence / Maria Blasco, Mike Khan --…”
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  6. 426

    Gene discovery for disease models

    Published 2011
    Table of Contents: “…Introduction : gene discovery-from positional cloning to genomic cloning -- High throughput gene expression analysis and the identification of expression QTLs -- DNA methylation in the pathogenesis of autoimmunity -- Ccell-based analysis with microfluidic chip -- Missing dimension : protein turnover rate measurement in gene discovery -- Bioinformatics tools for the prediction of gene function -- Determination of genomic locations of targeted genetic loci -- Mutation discovery using high throughput mutation screening technology -- Candidate screening through gene expression profile -- Candidate screening through high-density SNP array -- Gene discovery through direct genome sequencing -- Candidate screening through bioinformatics tools -- Using an integrative strategy to identify mutations -- Determination of the function of a mutant in a gene -- Confirmation of a mutation by multiple molecular approaches -- Confirmation of a mutation by microRNA -- Confirmation of function of a gene by translational approaches -- Confirmation of single nucleotide mutations -- Initial identification and confirmation of a QTL gene -- Gene discovery of crop diseases in the post genome era -- Impact of whole genome genetic element analysis on gene discovery of disease models -- Impact of whole genome protein analysis on gene discovery of disease models.…”
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  7. 427

    Computational methods in analysis of gene regulation and protein interactions

    Published 2012
    Table of Contents: “…Contents: Finding regulatory motifs -- Finding motifs using target sets of promoters -- Problem definition -- The Amadeus motif finding algorithm -- Architecture, benchmark results and global analysis -- Finding transcriptional programs and their regulatory motifs -- Problem definition -- The Allegro software for recovering transcriptional program -- Results on yeast osmotic shock expression profiles -- Recovering microRNA binding motifs from 3' UTRs using stem cell expression profiles -- Discovering a novel motif pair in C. elegans -- Utilizing network information -- Using expression and protein interaction data -- Problem definition and the Matisse algorithm -- Demonstration of Matisse on yeast osmotic shock data -- Comparison of Matisse to other algorithms -- Demonstration of Matisse on human stem cell data -- The pluripotency network -- Using expression and protein interaction data with interaction confidence -- The Cezanne algorithm -- DNA damage response in yeast.…”
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  8. 428

    Tracking vector insertion sites to explore the biology of transduced cells in vivo

    Published 2014
    Table of Contents: “…Contents: Clonal marking by integrating vectors -- Integration site analysis by LAM-PCR -- Analysis of gene therapy clinical trials for X-SCID, X-CGD, ADA-SCID & Cancer -- Avoiding oncogenesis in gene therapy -- Gene therapy for Wiskott-Aldrich Syndrome (WAS) -- Characterization & understanding of pathogenesis -- Integrations in known proto-oncogenes -- Possible triggers of AML development -- Safer vector systems & new technologies -- Lentiviral SIN-vectors -- Influence of vector type on clinical outcome -- LV integration site analysis: X-ALD trial -- Repopulation of hematopoietic system -- Targeted genome modification: nucleases -- Specificity of DNA modification by ZFN -- The TALEN nuclease and how it performs.…”
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  9. 429

    Feed efficiency in the beef industry

    Published 2012
    Table of Contents: “…Protein turnover and energy economy Chapter 8 The Potential Benefits of New Genomics Technologies The size and complexity of the genome The rationale for identifying polymorphisms Polymorphisms in junk DNA and in Biological relevant DNA such as gene promoter regions. …”
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  11. 431

    Medical imaging essentials for physicians / by Wolbarst, Anthony B.

    Published 2013
    Table of Contents: “…-- The creation of two-dimensional x-ray projection maps (shadowgrams) of the body : differential attenuation of x-rays by tissues -- 20th century (analog) radiography and fluoroscopy : capturing the x-ray shadow with a film cassette or with an image intensifier tube plus electronic optical camera combination -- Radiation dose and radiogenic risk : ionization-induced damage to DNA can cause stochastic, deterministic, and teratogenic health effects and how to prevent them -- 21st century (digital) imaging : computer-based representation, acquisition, processing, storage, transmission, and analysis of images -- Digital planar imaging : replacing film and image intensifiers with solid state, electronic image receptors -- Computed tomography : superior contrast in three-dimensional x-ray attenuation maps -- Nuclear medicine : contrast from differential uptake of a radiopharmaceutical by tissues -- Diagnostic ultrasound : contrast from differences in elasticity or density across tissue interfaces -- MRI in one dimension and without relaxation : a gentle approach to a challenging subject -- MRI with T1 and T2 relaxation and in three dimensions -- Evolving and experimental modalities.…”
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  12. 432

    Dendrimer-based drug delivery systems from theory to practice /

    Published 2012
    Table of Contents: “…. -- Triazine dendrimers for DNA and siRNA delivery : progress, challenges, and opportunities / Meredith A Mintzer ... …”
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  13. 433

    Biosensors properties, materials and applications /

    Published 2009
    Table of Contents: “…Catalase immobilized on nanohybrid materials for electrochemical hydrogen peroxide sensors : a review / Arun Prakash Periasamy, Yogeswaran Umasankar and Shen-Ming Chen -- Gold nanoparticle labelled DNA hairpin grafting on transparent and conductive oxide (TCO) films : characterization of grafting and hybridization / V. …”
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  14. 434

    Paediatric forensic medicine and pathology /

    Published 2008
    Table of Contents: “…Road traffic accidents in children / Anthony Busuttil -- 21. Forensic DNA profiling in cases involving children / Alex M. …”
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  15. 435

    Phycobiotechnology : biodiversity and biotechnology of algae and algal products for food, feed, and fuel /

    Published 2021
    Table of Contents: “…Jeya Bharathi -- Prospecting Microalgae for Biomolecules and Biofuels / Roshan Kumar, Sanniyasi Elumalai, and Sunil Pabbi -- Microalgal Biofuels: Current Status and Opportunities / Anurag Yadav and Kusum Yadav -- Biofuels from Microalgae: Future Bio-Energies for Sustainable Development / Ramganesh Selvarajan, Cecilia Oluseyi Osunmakinde, Timothy Sibanda, Anofi Ashafa, and Sanniyasi Elumalai -- Potential Health Benefits of Fucoidan: An Update / Thangaraj Vimala, Thinanoor Venugopal Poonguzhali, and Muthu Sakthivel -- Cyanobacteria as a Promising Source of Therapeutic Agents Against Various Human Diseases / Durdana Yasin, Nazia Ahmad, Moshahid Alam Rizvi, and Tasneem Fatma -- Evaluation of Methods of Biomass Recovery and Lipid Extraction for Microalgae / Mariana Lara Menegazzo, Jane Mary Lafayette Neves Gelinski, and Gustavo Graciano Fonseca -- DNA Rearrangements in Cyanobacterial Nitrogen Fixing Genes During Heterocyst Development / Neha Sami and Tasneem Fatma -- Determination of Kinetic Parameters for Biotechnological Applications With Microalgae / Nathanya Nayla De Oliveira, Mariana Lara Menegazzo, and Gustavo Graciano Fonseca -- Biotechnology of Microalgae: A Green Approach Towards Exploitation of Omega-3 Fatty Acids / Ramu Manjula and Manjunath Chavadi -- Genetic Engineering as a Tool for Improved Applications of Algae / Annamalai Jayshree -- Algal Pathways and Metabolic Engineering for Enhanced Production of Lipids, Carbohydrates, and Bioactive Compounds / Mohd. …”
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  16. 436
  17. 437

    Achieving justice in genomic translation re-thinking the pathway to benefit /

    Published 2011
    Table of Contents: “…Edwards -- The social, political, and economic underpinnings of biomedical research and development: a formidable status quo / Patricia Kuszler -- The input-output problem: whose DNA do we study, and why does it matter? / Stephanie Malia Fullerton -- The autism genetic resource exchange: changing pace, priorities, and roles in discovery science / Holly K. …”
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  18. 438

    Advancements in cancer research

    Published 2012
    Table of Contents: “…An outlook on uterine neoplasms : from hormonal and DNA damaging to cervical and endometrial cancer development and minimally invasive management / Andrea Tinelli ... …”
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  19. 439

    Genotoxicity evaluation, testing and prediction /

    Published 2009
    Table of Contents: “….] -- Usefulness of bulky DNA adduct formation as a biological marker of exposure to airborne particulate matter (Pm2.5) in in vitro cell lung models : a comparative study / Sylvain Billet ... …”
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