Search Results - "DNA"

Human evolution

Table of Contents: “…Contents: Human evolution from the fossil record -- Early hominid lineages in and out of Africa -- The genomic revolution -- The advent of ancient DNA -- Archaic admixture -- Sedimentary DNA -- Paleoproteomics -- Natural selection in humans in the past and present.…”
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Next generation sequencing in genetic diagnostics

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Epigenetics in age-related macular degeneration

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The chloroplast genome and chloroplast gene expression

Subjects: “…Chloroplast DNA. 83145…”
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The future of CNVs sequence based resolution and links to human disease, part 1 of 2 /

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Series (Copy number variation)
Series (Biomarkers)

The Myc transcription factor network

Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)

The future of CNVs sequence based resolution and links to human disease, (part 2 of 2) /

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Series (Copy number variation)
Series (Biomarkers)

Introduction to epigenetics

Table of Contents: “…Contents: Definition of epigenetics -- Three mechanisms; DNA methylation, histone modification, ncRNA -- Hypo and hyper DNA methylation and association with transcriptional state -- Mechanism of DNA methylation and enzymes responsible -- Examples of importance of DNA methytransferase enzymes -- Main types of histone modifications, concentrating on acetylation and methylation -- Mechanisms and enzymes for histone modifications -- Example of gene regulation by acetylation/deacetylation in Arabidopsis -- Non-coding RNA, using X-inactivation as an example -- The histone code.…”
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Fertilization

Table of Contents: “…Contents: Sperm transport along the male tract -- Sperm transport along the female tract -- Capacitation and acrosome reaction -- Transport of oocytes to the fertilization site -- Penetration through the egg investments -- Recognition, binding and fusion of sperm to the oocyte membrane -- Activation of the oocyte and cortical reaction -- Resumption of the second meiotic division -- Pronuclear development and DNA replication -- Sperm contribution to the developing embryo.…”
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An expendable man the near-execution of Earl Washington, Jr. / by Edds, Margaret, 1947-

Subjects: An electronic book accessible through the World Wide Web; click to view

Omic association studies with R and Bioconductor / by González, Juan R. (Bioinformatics researcher), Cáceres, Alejandro (Bioinformatics researcher)

Subjects: Taylor & Francis
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Mitochondrial diseases an update /

Table of Contents: “…Contents: Mitochondria and mitochondrial biogenesis -- mtDNA and nucleoids -- The electron transport chain -- Epidemiology of mitochondrial diseases -- Heteroplasmy -- Mitochondrial diseases -- Adult and childhood onset of mitochondrial diseases (POLG, MELAS, LHON, KSS, Leigh syndrome) -- Treatment of mitochondrial diseases -- Mitochondrial-dysfunction related disorders.…”
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Series (Mitochondrial biogenesis)

Genetic basis of neurological disease

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Epigenetics and inheritance

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Heritability and its uses

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Linkage and sequence analysis in families

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Turning genomic junk into treasure genetic engineering with the Sleeping Beauty transposon system /

Table of Contents: “…Contents: Transposons can be viewed as natural DNA transfer vehicles -- Transposons are capable of efficient genomic insertion, similar to integrating viruses -- Transposition can be controlled by conditionally providing the transposase enzyme -- DNA of interest cloned into a transposon-based vector can be utilized for stable genomic insertion in a regulated and highly efficient manner -- Transposition opens up many avenues for genome manipulations in vertebrates -- Generation of transgenic cells and germline-transgenic animals using transposons -- The Sleeping Beauty synthetic transposon -- Clinical applications of the Sleeping Beauty system.…”
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Mitochondrial and lysosomal dysfunction in the pathogenesis of Parkinson's disease

Table of Contents: “…Contents: Pathogenesis of Parkinson's disease (PD) -- Mitochondria (biochemistry, DNA, proteins, turnover) -- Oxidative phosphorylation and respiratory chain -- Fraction of deleted mtDNA in substantia nigra (SN) -- Mitochondrial complex I deficiency in PD -- PARK loci -- The role of mitophagy in mitochondrial turnover -- Common pathways underlying PD pathogenesis -- Ageing and PD pathogenesis -- Autosomal mitochondrial diseases -- POLG mutations -- Alpha-synuclein (SNCA) and mitochondria -- Autophagy, lysosomal dysfunction and Glucocerebrosidase (GCase) -- Gaucher disease -- Chaperone-mediated autophagy: LAMP-2A -- GBA mutations -- DAT density and disease progression in PD -- DaTScan in genetic PD -- GCase-SNCA as a target for PD -- GBA & GBA-SNCA pathway as targets for PD therapies.…”
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Accessing and using ENCODE data

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Series (Eukaryotic gene regulation)
Series (Introduction to human genetics)
Series (Using bioinformatics in the exploration of genetic diversity)
Series (Epigenetics, chromatin, transcription and cancer)

Vitiligo in vivo and in vitro evidence for epidermal ROS/RNS-mediated regulation/dysregulation /

Table of Contents: “…Contents: Role of inherited vs. induced (tanning) skin colour -- Enhanced pigmentation after sun exposure -- Vitiligo and its characteristics (inherited skin colour loss) -- Correct diagnosis of vitiligo via characteristic fluorescence -- Use of Wood's light for differential diagnosis -- Cause and pathogenesis of vitiligo -- Oxidation and nitration of proteins and peptides in vitiligo and their effects -- DNA damage, T-cell response & p53 in vitiligo -- Treating vitiligo: Reducing oxidation and repigmentation.…”
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