Rezultaty - protein secondary structure

Molecules nucleation, aggregation and crystallization : beyond medical and other implications /

Spis treści: “…I. homology modeling and prediction of the secondary and tertiary structure / Jan Pawel Jastrzebski and Jan Sedzik -- In meso approaches to membrane protein crystallization / Valentin I. …”
An electronic book accessible through the World Wide Web; click to view

Medicinal plant biotechnology

Spis treści: “…Don. for augmenting secondary metabolite production / Rajesh Arora ... …”
An electronic book accessible through the World Wide Web; click to view

Polypharmacology in drug discovery

Spis treści: “…Car 2 Screening for safety-relevant off-target activities Laszlo Urban, Steven Whitebread, Jacques Hamon, Dmitri Mikhailov and Kamal Azzaoui 2.1 Introduction. 2.2 General aspects. 2.3 Selection of off-targets. 2.4 In silico approaches to off-target profiling .2.5 Summary and conclusions. 3 Pharmacological promiscuity and molecular propertiesJens-Uwe Peters 3.1 Introduction: pharmacological promiscuity in the history of drug discovery. 3.2 Lipophilicity. 3.3 Molecular weight. 3.4 Ionisation state. 3.5 Other molecular descriptors and structural motifs. 3.6 Implications for drug discovery. 4 Kinases as antitargets in genotoxicity Stephan Kirchner 4.1 Protein Kinases and inhibitor-binding sites. 4.2 Cyclin-Dependent Kinases (CDKs) controlling unregulated cell proliferation. 4.3 Mitotic kinases as guardians protecting cells from aberrant chromosome segregation. 5 Activity at cardiovascular ion channels: a key issue for drug discoveryIan M. …”
An electronic book accessible through the World Wide Web; click to view