Search Results - "Stem Cells."

Translating retinal stem cells

Table of Contents: “…Contents: Retinitis pigmentosa -- Stem cell therapy -- Intracerebral retinal transplantation -- Transplantation of neural stem cells -- Retinal progenitor cell transplantation -- Characterization of hRPCs -- In vivo studies -- Allogeneic transplantation -- Clinical development.…”
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Niche oncogenesis

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Genes & cells therapy

Table of Contents: “…Contents: The use of human autologous stem cells in patients that suffer from liver diseases -- Stem cells specialize in repairing damaged tissues and regenerating damaged organs -- Omnicyte is a particular type of CD34+ hematopoietic stem cell -- Hematopoietic stem cells ability to expend and proliferate -- Expression of genes associated with the hepatocyte cells phenotype -- The effect of injecting human autologous stem cells into patients with liver insufficiency -- Normalization of albumin and bilirubin levels in patients with liver disease -- Results of phase II clinical trials.…”
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Primary and stem cell transplantation for functional repair of striatal degeneration in Parkinson's and Huntington's disease

Table of Contents: “…Contents: Neural transplantation of primary fetal tissue and stem cells -- Parkinson's and Huntington's disease -- Dopaminergic and medium spiny neurons -- Results of clinical trials -- Pre-clinical testing in rodent models of disease.…”
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Hematopoietic stem cell gene therapy for the treatment of metachromatic leukodystrophy

Table of Contents: “…Contents: Metachromatic Leukodystrophy (MLD) -- Hematopoietic stem cell therapy (HCT) for lysosomal storage disorders (LSDs) -- Improving HCT efficacy -- The role of brain pre-conditioning -- Mechanisms of microglia turnover -- Gene therapy (GT) & enzyme release -- Gene therapy in murine models -- HSC gene therapy for MLD -- Lentivirus integration site analysis -- Stem cells analysis -- ARSA activity and delivery to the CNS -- Cerebral and peripheral demyelination -- Motor function testing (GMFM).…”
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Cell replacement therapy for neurodegenerative diseases

Table of Contents: “…Contents: Parkinson's Disease and therapies available -- Preclinical data supporting cell therapies for Parkinson's -- Clinical data on fetal transplant trials in Parkinson's -- Development of stem cell-derived dopamine neurons -- Huntington's Disease and therapies available -- Preclinical data supporting cell therapies for Huntington's -- Clinical data on fetal transplant trials in Huntington's -- Development of stem cell-derived medium spiny neurons.…”
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Novel treatments for GI malignancies

Table of Contents: “…Contents: HER2 and colorectal cancer -- BRAF mutated colorectal cancer -- Targeting cancer stem cells.…”
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Series (Cancer therapies in the personalized medicine era)
Series (Gastroenterology and hepatology)

The evolving role of novel and next generation therapies in the management of multiple myeloma part 1 of 2, introduction and current therapies /

Table of Contents: “…Contents: Multiple myeloma and key targets in 2019 -- Principles of initial therapy in stem cell transplant -- Therapeutics and drug agents used in Multiple Myeloma.…”
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Increasing tumor targeting efficacy by nanomedicine

Table of Contents: “…Contents: Rationale: low target efficacy drugs -- Physiochemical properties of nanoparticles -- Mesenchymal stem cell-nanodrug delivery -- Transportation to cancer organelles.…”
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Natural Killer cells as COVID-19 therapy

Table of Contents: “…Contents: The role of Natural Killer (NK) cells in viral infections -- Why NK cells are being investigated -- Induced pluripotent stem cell derived natural killer cells for SARS-CoV-2 therapy -- Benefits of this therapy -- Current stage of the clinical trial.…”
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Parkinson's disease and transplants

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CRISPR editing therapy for Duchenne Muscular Dystrophy part 1 of 2 /

Table of Contents: “…Contents: Duchene Muscular Dystrophy (DMD) -- Dystrophin function -- MDX mouse model -- AAV CRISPR local therapy in mice -- AAV CRISPR systemic therapy in mice -- Myogenic stem cells can be transduced and edited by AAV9 CRISPR therapy.…”
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Helper-dependent adenoviral vectors for gene therapy

Table of Contents: “…Contents: Overview of gene therapy vectors -- Helper-Dependent Ad (HDAd) vector -- Liver and lung directed gene therapy -- Hemophilia B gene therapy -- OTC deficiency clinical trial -- Balloon occlusion catheter-based delivery of HDAd -- HDAd-mediated CF gene therapy -- Brain gene therapy -- HDAd as genetic vaccine -- HDAd and stem cells.…”
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Mechanistic aspects and therapeutic applications of RNAi

Table of Contents: “…Contents: RNAi mechanisms -- RNAi and HIV infection -- Lentiviral vector-mediated transduction of stem cells and T-cells -- Gene therapy based treatment of HIV-1 -- HIV mutants that abrogate RNAi -- Multiplexing different siRNAs and siRNAs with other antiviral RNAs to minimize viral resistance -- An HIV Tat inducible shRNA expression system -- Multiplexing shRNA with dominant negative M10 protein inhibition of HIV.…”
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