Search Results - "vaccination"

Cancer vaccines part 2 of 2 /

Table of Contents: “…Contents: HPV infection & prevention strategies -- Global cervical cancer prevalence -- HPV induced lesions & cancers -- Cell-mediated immune response to HPV -- Synthetic Long Peptide (SLP) vaccine concept -- Vulval intraepithelial neoplasia (VIN) vaccine -- Combining chemotherapy & SLP vaccination.…”
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Series (Vaccines)

Antivirals versus vaccines

Table of Contents: “…Contents: Emerging infections in the past decades -- Human respiratory viruses -- The AIDS pandemic -- HIV vaccine approaches -- Antivirals use against HIV -- Morbilliviruses -- Metapneumovirus -- hMPV -- SARS-CoV -- Candidate SARS vaccines -- Vaccination of macaques against SARS -- Henipahvirus -- Smallpox -- History of smallpox vaccination -- Antiviral drugs against smallpox -- Cidofovir -- Human influenza: three appearances -- Avian influenza A virus: adaptation -- H1N1 virus: relevant mutations -- The Mexican flu virus -- Pre-pandemic H5N1 clinical trials -- The importance of an adjuvant -- Seasonal vaccine and pandemic A/H1N1 -- Flu drugs targets.…”
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The future of influenza vaccines

Table of Contents: “…Contents: Influenza virion structure -- Available flu vaccines -- Problems with current inactivated vaccines -- Live attenuated vaccines -- Subunit vaccine -- New, recently licensed vaccines -- Flu vaccines in development -- Experimental vaccines -- Issues with pandemic vaccines -- Universal influenza vaccines -- The HA protein.…”
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Vaccines as a weapon against antibiotic resistance

Table of Contents: “…Contents: Overview of antibiotic resistance -- WHO Global Action Plan against resistance -- WHO's prioritization of pathogens -- Research discovery against new antibiotics -- Vaccines to combat antibiotic resistance -- Vaccine development against selected WHO prioritized pathogens.…”
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Vaccines and the fight against antimicrobial resistance 2

Table of Contents: “…Contents: Vaccines in late-stage development with a potential to reduce AMR -- Vaccines in early-stage development with a potential to reduce AMR -- Global mobilization actions utilizing vaccines against AMR -- The Davos Declaration -- Barriers to maximizing licensed vaccine use in fighting AMR -- Efforts towards better utilization of vaccines against AMR.…”
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Emergence of blood clotting disorders resulting from COVID vaccines inoculations

Table of Contents: “…Contents: The frequency of clotting side-effects in COVID-19 vaccines -- The characteristics of these side-effects and how they compare to other clotting disorders -- What is known regarding the mechanisms underlying these side effects -- What is known regarding populations at greater risk of suffering these side effects.…”
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Eliminating human rabies deaths part 2 of 2, targeting the elimination of rabies /

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Can HPV testing be the sole primary cervical screening modality?

Subjects: “…Papillomavirus Vaccines therapeutic use. 109161…”
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Risk factors for antibiotic resistance in Streptococcus pneumoniae

Table of Contents: “…Contents: Antibiotic use as a driver of resistance in Streptococcus pneumoniae at the country, provincial and individual level -- Drivers of multiple resistance -- Conjugate pneumococcal vaccine impact on antibiotic resistance in the pneumococcus.…”
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Subversion of complement by bacteria

Table of Contents: “…Contents: Innate immunity -- Complement -- Self/nonself discrimination -- Borrelia escape from the immune system -- Microbes that similarly inhibit the complement system -- Vaccines based on microbial complement inhibitors.…”
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Hepatitis C cure of infection /

Table of Contents: “…Contents: HCV: major milestones -- Hepatitis C virus & infection -- Hepatocellular cancer -- HCV natural history and therapy -- HCV RNA and protein -- HCV genotypes and subtypes -- Hepatitis C vaccine -- Direct acting antivirals (DAAs).…”
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RNA therapeutics clinical applications and methods of delivery /

Table of Contents: “…Contents: The diversity of RNA species -- The diversity of mRNA -- mRNA vaccines -- mRNA vs. viral vector vaccines -- Obstacles overcome -- The limitless potential of RNA therapeutics -- VEGF mRNA for ischemia -- mRNA for cystic fibrosis -- Roadmap for RNA therapeutics -- RNA therapeutics and cancer -- Innovation in RNA therapeutics -- aYAP mRNA for cardiac regeneration -- mRNA therapy for progeria (HGPS).…”
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Parasite immunity part 1, Introduction and plasmodium /

Table of Contents: “…Contents: Plasmodium falciparum -- Malaria -- Vaccines -- Size and parasites -- Parasitic survival strategies -- Anopheles gambiae -- Plasmodium lifecycle -- Sporozoites -- Merozoites -- Circumsporozoite protein -- Infected red blood cells -- Cytoadherence -- Rosetting -- Monoclonal antibodies.…”
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The evolving role of novel and next generation therapies in the management of multiple myeloma part 2 of 2, relapse refractory multiple myeloma /

Table of Contents: “…Contents: T-cell therapy strategies for Multiple Myeloma -- Cell-based Myeloma vaccines -- Antibody-drug conjugates -- Continuing evolution of Multiple Myeloma treatment.…”
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Immune checkpoint blockade in CNS tumors

Table of Contents: “…Contents: Immunotherapy in oncology -- CNS immunoprivilege -- Glioblastoma (GBM): complexity/redundancy/heterogeneity -- "Established" and "Advanced" GBM models -- Tumor-specific immune response in GBM -- Importance of heterogeneity -- Overcoming challenges for durable GBM benefit -- Neoantigen mutations -- Checkpoint blockade & immunologic memory -- GBM vaccines -- Personalized neoantigen vaccine ("NeoVax") -- Immunotherapy response assessment in neuro-oncology (iRANO) -- Clinical trials in neuro-oncology -- Immunosuppressive mechanisms in GBM -- Combination anti-tumor immunotherapy.…”
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Helper-dependent adenoviral vectors for gene therapy

Table of Contents: “…Contents: Overview of gene therapy vectors -- Helper-Dependent Ad (HDAd) vector -- Liver and lung directed gene therapy -- Hemophilia B gene therapy -- OTC deficiency clinical trial -- Balloon occlusion catheter-based delivery of HDAd -- HDAd-mediated CF gene therapy -- Brain gene therapy -- HDAd as genetic vaccine -- HDAd and stem cells.…”
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Interferons as antivirals translating basic research into clinical application /

Table of Contents: “…Contents: Emerging and re-emerging virus infections globally -- Time lag before a new vaccine is available during a pandemic -- Antivirals that are pathogen specific lead to viral resistance -- Broad spectrum antivirals needed -- Interferons -alpha -beta are produced in response to all virus infections -- Every cell/tissue will respond to interferon -- Widespread application for all virus infections.…”
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Prion-like propagation of Parkinson's disease

Table of Contents: “…Contents: Parkinson's disease : symptoms and pathology (PD mutations and risk factors) -- Braak staging of Lewy body-related pathology in PD -- The prion-like hypothesis -- Key steps of alpha-synuclein pathology propagation (Release, Uptake, Seeding, Transport) -- In vivo and cell models from different species -- Therapeutic targets: promoting degradation, antibody aided clearance, and preventing seeding of alpha-synuclein -- Parkinson's disease vaccine: first clinical studies.…”
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Novel immunotherapeutic proteins immunoligand /

Table of Contents: “…Contents: Potential advantages of mAB -- Challenges for mAB -- Antibody based therapeutic proteins -- Attributes of immunoligands -- Creation of Ig-based fusion proteins -- Non-cytolytic IL-2/Fc fusion protein -- Vaccine trial design -- Creation of cytolytic IL-15R antagonist fusion protein -- Application of immunoligand: immunogen for mAB production, to stain the cognate ligand, to identify cell surface cognate ligands via immunoprecipitation, to create long lived proteins to test the function of the targeting ligand in vivo and to modulate immune responses -- Challenges for immunoligands.…”
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Mismatch repair deficient cancers diagnosis, treatment and prevention

Table of Contents: “…Contents: Lynch syndrome (underlying single gene defect) -- Microsatellites -- Important genes containing repeat sequences -- MSI testing (5 marker panel) -- Mismatch repair (MMR) -- The genomic pathogenesis of colorectal cancer (CRC) -- EGFR and BRAF mutant inhibition -- BRAF colon cancer project -- Methotrexate & MMR deficient tumours -- Africans & bowel cancer (Dennis Burkitt) -- Cancer prevention program (CaPP) -- NSAIDs and reduced colorectal cancer risk -- Aspirin effect on polyps in FAP and colorectal adenoma -- The prevention paradox -- CaPP2 (Colorectal & Lynch syndrome cancers) -- Meta-analysis of cancer deaths with aspirin treatment -- CRCs in people on aspirin (mostly COX2 negative) -- Individual response to aspirin in cancer prevention -- History of salicylate as an essential nutrient -- CaPP3 study -- Peptides created by slippage in microsatellite coding -- Antibodies as a possible biomarker for Lynch syndrome -- The Micoryx vaccine.…”
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