Search Results - "DNA"

The role of phosphorylation in mediating cellular responses to DNA damage the ATM-mediated DNA damage response /

Table of Contents: “…Contents: Endogenous DNA damage in mammalian cells -- DSB repair pathways -- Cellular responses to DNA damage -- Genomic instability syndromes -- Ataxia-telangiectasia -- The ATM protein -- ATM-mediated DNA damage responses -- A SPIKE map -- Defective repair of DNA double strand breaks -- Allowing repair to happen within chromatin -- DNA damage response and the ubiquitin family -- Players in ubiquitin-related processes -- Phosphoproteome dynamics after DNA damage -- Functional networks of phosphorylated proteins -- Overlap between Ub, ATM and phosporylation -- Functional screens for novel DDR players.…”
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Gene structure, expression and regulation DNA structure and replication /

Table of Contents: “…Contents: DNA structure -- DNA replication process -- DNA replication is continuous just on one strand -- Initiation of replication occurs at origin (oriC) -- Elongation of replication -- DNA replication in humans -- The transcription process -- Initiation of transcription in eukaryotic cell -- Elongation of transcription and termination -- Maturation of RNA and splicing -- Additional post transcription modification.…”
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Virology and cancer biology part 2, DNA viruses associated with transformation and tumor formation : the discovery of tumor suppressor genes /

Table of Contents: “…Contents: DNA viruses and transformation -- Viral T antigen and cell cycle control -- The linkage between Cell cycle, T antigens, Rb, E2F and p53 -- Transformation as an epiphenomenon of DNA viruses.…”
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O-GlcNAc, an essential regulator of numerous cellular pathways

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Role of polycomb proteins in gene transcription, stem cell and human diseases

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Gene structure, expression and regulation translation and regulation of gene expression /

Subjects: “…DNA. 88312…”
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Mitochondria in reproduction and fertility part 2, mitochondria & embryo /

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The Myc transcription factor network

Table of Contents: “…Contents: Myc plays a broad role in cellular functions -- Deregulation of Myc is associated with many cancers -- Myc and Mxd proteins heterodimerize with Max, bind DNA, and activate or repress transcription through recruitment of co-regulator complexes that in turn influence chromatin modifications -- Myc family proteins are highly conserved and regulate cell growth by binding to many genes involved in translation and metabolism -- Myc also has functions unrelated to transcription -- Update talk: The MYC transcription factor network -- Update talk: Interactions of MYC with other cellular proteins -- Update talk: Topologically Associated Domains (TADs) -- Update talk: Transcriptional functions of MYC -- Update talk: Proximal MYC network -- Update talk: New approaches to inhibiting MYC activity.…”
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Series (Cell division cycle)
Series (Epigenetics, chromatin, transcription and cancer)

Fertilization

Table of Contents: “…Contents: Sperm transport along the male tract -- Sperm transport along the female tract -- Capacitation and acrosome reaction -- Transport of oocytes to the fertilization site -- Penetration through the egg investments -- Recognition, binding and fusion of sperm to the oocyte membrane -- Activation of the oocyte and cortical reaction -- Resumption of the second meiotic division -- Pronuclear development and DNA replication -- Sperm contribution to the developing embryo.…”
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Mitochondrial diseases an update /

Table of Contents: “…Contents: Mitochondria and mitochondrial biogenesis -- mtDNA and nucleoids -- The electron transport chain -- Epidemiology of mitochondrial diseases -- Heteroplasmy -- Mitochondrial diseases -- Adult and childhood onset of mitochondrial diseases (POLG, MELAS, LHON, KSS, Leigh syndrome) -- Treatment of mitochondrial diseases -- Mitochondrial-dysfunction related disorders.…”
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Series (Periodic reports)
Series (Mitochondrial biogenesis)

Epigenetics and inheritance

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Mitochondria and ageing in model systems

Table of Contents: “…Contents: Mitochondria function/dysfunction and related outcomes -- Metabolic rate theory of aging -- Beneficial effects of caloric restriction -- ROS production and oxidative stress effect on aging -- Free radical theory of aging -- Mitochondrial DNA mutations phenotypes.…”
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The transcription factor NF-Kappa B an evolutionarily conserved mediator of immune and inflammatory responses /

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Histone dynamics, heritability and variants

Table of Contents: “…Contents: DNA is organized into chromatin which promotes compaction and brings about additional information -- The histone code hypothesis -- Chromatin dynamics and heritability -- Factors involved in chromatin dynamics -- Nucleosomes disruption and assembly following DNA replication fork passage -- General steps in chromatin assembly -- Histone chaperones and their possible roles (CAF-1, HIRA, ...) -- Histone H3 variants and chromatin assembly coupled or not with DNA synthesis -- Specific histone deposition pathways for each variant? …”
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Series (Epigenetics : concepts, theories, paradigms and mechanisms)
Series (Eukaryotic gene regulation)
Series (Epigenetics, chromatin, transcription and cancer)

Skin epigenetics how chromatin regulators orchestrate skin functions /

Table of Contents: “…-- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.…”
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Oxidative stress in amyotrophic lateral sclerosis (ALS) part 2 of 2 /

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Protein networks and analysis of global gene expression

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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Mechanisms of transcription the eukaryotic pre-initiation complex /

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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Pre-mRNA splicing

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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Self-splicing intron RNAs ribozymes, parasites and agents of genomic change /

“…Biomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation.…”
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