Search Results - "prion"
Suggested Topics within your search.
Suggested Topics within your search.
- pathology
- Alzheimer Disease 3
- Alzheimer's disease 3
- Degeneration 3
- Nervous system 3
- Neurodegenerative Diseases 3
- Chemotherapy 2
- Parkinson Disease 2
- Parkinson's disease 2
- Prion Diseases 2
- Prion diseases 2
- drug therapy 2
- etiology 2
- genetics 2
- metabolism 2
- Amyloid 1
- Amyloid beta-Peptides 1
- Amyloid beta-protein 1
- Brain 1
- Dementia 1
- Diagnosis 1
- Genetic aspects 1
- Lewy Bodies 1
- Lewy body dementia 1
- Memory Disorders 1
- Muscarinic receptors 1
- Neurons 1
- Neuroprotective Agents 1
- Pathogenesis 1
- Pathology 1
-
1
Prion-like propagation of Parkinson's disease
Published 2014Table of Contents: “…Contents: Parkinson's disease : symptoms and pathology (PD mutations and risk factors) -- Braak staging of Lewy body-related pathology in PD -- The prion-like hypothesis -- Key steps of alpha-synuclein pathology propagation (Release, Uptake, Seeding, Transport) -- In vivo and cell models from different species -- Therapeutic targets: promoting degradation, antibody aided clearance, and preventing seeding of alpha-synuclein -- Parkinson's disease vaccine: first clinical studies.…”
Get full text
Series
Electronic Video -
2
Novel approaches to treating symptoms and slowing the progress of neurodegenerative diseases
Published 2019Table of Contents: “…Contents: Brief overview of dementia -- Current treatments for Alzheimer's disease -- Role of muscarinic receptors in learning and memory -- Using prion disease as a model -- Effects of muscarinic receptor drugs on learning and memory deficits in prion disease -- Types of drugs for different stages of Alzheimer's disease.…”
Get full text
Series
Electronic Video -
3
Neurodegenerative disease expression levels of normal sequence pathogenic proteins contribute to risk of disease /
Published 2021Table of Contents: “…Contents: Protein pathology of disease -- Loci underlying autosomal dominant neurodegenerative disease -- Prion mutations causing Gerstmann Straussler syndrome and hereditary Creuzfeldt-Jakob disease -- Tau mutations cause autosomal dominant frontal temporal dementia -- Alpha-synuclein mutations cause autosomal dominant Parkinson's disease -- How genetic variability of these genes contributes to the risk of sporadic disease.…”
Get full text
Series
Electronic Video -
4
Targeting Aß oligomers a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease /
Published 2014Table of Contents: “…Contents: The oligomer cascade hypothesis for Alzheimer's Disease -- Why the oligomer hypothesis has largely supplanted the amyloid cascade hypothesis -- The role of AβOs in memory failure and the major facets of AD neuropathology -- Mechanisms by which AβOs instigate neurotoxicity -- Why AβOs accumulate in the first place -- How AβOs offer superb targets for novel AD diagnostics and disease-modifying therapeutics -- Beside its direct link to Alzheimer's disease, the discovery of toxic Aβ oligomers has provided a novel structural archetype for toxins germane to more than two dozen diseases of protein mis-folding, including Diabetes, Parkinson's, and prion diseases.…”
Get full text
Series
Electronic Video