Search Results - muleta~
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- methods
- Statistical methods 6
- Data Interpretation, Statistical 4
- Models, Statistical 4
- statistics & numerical data 4
- Clinical trials 3
- Computational Biology 3
- Genetics 3
- Genome-Wide Association Study 3
- Statistics as Topic 3
- Bioinformatics 2
- Biometry 2
- Biostatistics 2
- Chromosome Mapping 2
- Clinical Trials as Topic 2
- Computer Graphics 2
- Computer Simulation 2
- Design 2
- Endpoint Determination 2
- Gene mapping 2
- Haplotypes 2
- Methodology 2
- Models, Genetic 2
- Population genetics 2
- Randomized Controlled Trials as Topic 2
- Research 2
- Research Design 2
- standards 2
- Adaptive sampling (Statistics) 1
- Algorithms 1
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1
Treatment effect estimates in multi-arm multi-stage (MAMS) clinical trials
Published 2020Get full text
Series
Electronic Video -
2
A concept for multi-marker approaches in clinical proteomics
Published 2013Get full text
Series
Electronic Video -
3
Winner's curse, replication and meta-analysis
Published 2016Table of Contents: “…Contents: Winner's curse: tendency to see a larger effect than usual upon discovery -- Examples from GWAS -- Methods for obtaining unbiased estimates -- Replication: confirming genetic associations in further studies -- Technical, direct and indirect replication -- Meta-analysis: combining multiple GWAS -- Forest plots, fixed and random effects, sources of heterogeneity in GWAS.…”
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Series
Electronic Video -
4
Surrogate endpoints, part 1 from definition to meta-analytic framework /
Published 2019Table of Contents: “…Contents: Discrete surrogates -- Prentice's definition -- Subsequent developments -- Single-trial validation framework -- Meta-analytic frameworks.…”
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Series
Electronic Video -
5
Phase II clinical trials traditional approaches /
Published 2018Table of Contents: “…Contents: Frequentist methods -- Non-adaptive trial design -- Single stage single outcome design -- Randomized dose-ranging design -- Controlled titration design -- Adaptive trial designs -- Single outcome multi-stage designs -- Multiple outcomes multi-stage design.…”
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Series
Electronic Video -
6
Tuberculosis new treatments in evolution /
Published 2014Table of Contents: “…Contents: Tuberculosis history -- The streptomycin trial -- Headlines in tuberculosis drug development -- Standard treatment for drug-sensitive TB -- Toxicity -- Treatment duration -- Challenges in TB treatment -- Some examples of drugs in development -- New trials to shorten treatment for TB -- Fluoroquinolones for TB -- Johns Hopkins study -- REMoxTB study objective -- Overview of TB microbiology protocols -- Safety -- Gatifloxacin project: phase III -- More TB drug development approaches -- New combination regimen studies -- MAM- multi arm multi stage -- Developing new treatments for MDR/XDRTB -- Current WHO treatment for MDRTB -- Using existing and repurposed drugs -- New drugs for MDRTB (Delanamid, Bedaquinline) -- Drugs in development for MDR indication.…”
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Series
Electronic Video -
7
Atypical disfluency understanding and treating word-final (end-word) repetition /
Published 2017Table of Contents: “…Contents: Atypical speech disfluency (word-final repetition) in comparison to stuttering -- Multi-dimensional profiles of word-final disfluency in children with & without autism -- Considerations for treatment planning -- Short-term behavioral treatment -- Case studies in neurotypical children and children with autism.…”
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Series
Electronic Video -
8
Inferring relatedness
Published 2016Table of Contents: “…Contents: Genetic consequence of relatedness -- From pedigree to genome -- IBD, Identity-By-Descent -- Kinship coefficient -- Inbreeding Coefficient -- Identity Coefficients -- Models and methods to infer IBD from genotypes: Single-point, Segmental sharing, Multi-point (hidden Markov model) -- Applications: Population Genetics, Disease Gene Mapping.…”
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Series
Electronic Video -
9
Genetic association analysis with R
Published 2009Table of Contents: “…Contents: R environment for statistical analysis -- Rationale of R for genetic data -- Use of packages -- Haplotype analysis -- Regional association -- The Framingham data -- GenABEL -- Q-Q and Manhattan plots -- GWAS -- Issues and challenges -- Meta-analysis -- Use of publically available data -- A technical summary.…”
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Electronic Video -
10
Imputation in genome-wide association analysis
Published 2017Table of Contents: “…Contents: The general problem of imputation -- Testing imputed SNPs for association -- Examples of imputation in the WTCCC -- Properties of imputation (LD, populations, chips, allele frequency) -- Using imputed data for meta-analysis -- The Strand Issue and Imputation QC metrics -- The 1000 Genomes Project -- Pre-phasing and haplotype estimation -- The Haplotype Reference Consortium.…”
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Series (Statistical methods for the analysis of genome-wide association studies)
Series (Statistical genetics)
Electronic Video -
11
Use of technology and document management systems for SOPs
Published 2013Table of Contents: “…Contents: Using technology or EDMS for SOPs -- The place of paper and of technology -- A basic EDMS -- What to expect from your EDMS -- Meta data -- Document versioning, publishing & security -- Collaborative creation -- Work flow -- Electronic signatures -- Linking documents -- Guidance for associated documents -- Forms & templates -- Using a bridging document -- Thoughts for the future.…”
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Series
Electronic Video -
12
A versatile platform for multilevel modeling of physiological systems
Published 2014Table of Contents: “…Contents: Multi-level modeling -- Physiome database and mathematical modeling -- PhysioDesigner, PHML, simulator & databases -- Module and physical-quantity -- Mathematical expressions in a model -- Reuse of modules -- SBML-PHML hybrid modeling -- Template and instance framework -- Integration of time series data and morphology -- Physical-quantity assigned to time-series data -- Modeling with morphology -- Image processing for integrating morphology -- Manipulation on medical images -- Integrating morphology with Poisson differential equations (PDEs) -- Flint simulator -- Visualization by PhysioVisualizer and in 3D morphology space -- Physiome.jp and PH database -- Inter-operation and linkage among applications (Garuda).…”
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Series
Electronic Video